Author(s): Mohammed M. Safhi, S.M. Sivakumar, Aamena Jabeen, N.Sukumaran

Email(s): drsmsivakumar@gmail.com

DOI: Not Available

Address: Mohammed M. Safhi1, S.M. Sivakumar1*, Aamena Jabeen1, N.Sukumaran2
1Department of Pharmacology and Division of Pharmaceutical Biotechnology, College of Pharmacy, Jazan University, Jazan, Kingdom of Saudi Arabia
2Sri Paramakalyani Centre for Environmental Sciences, Manonmaniam Sundaranar University, Tirunelveli, India
*Corresponding Author

Published In:   Volume - 7,      Issue - 10,     Year - 2014


ABSTRACT:
Vaccines are considered as the most successful medical invention against various infectious diseases. However, there are significant barriers for improving immune response especially with recombinant vaccines. Therefore, immunopotentiators (adjuvants) are included in vaccine formulation in order to augment immune response. The present study was aimed to alter the alum type adjuvant for hepatitis B vaccine. The hepatitis B vaccine was encapsulated in dextran microparticles by emulsion cross linking technique. The formulated microparticles were characterized in terms of morphology, particle size analysis and in vitro release study. In this study we could not demonstrate the dextran microparticle system as an adjuvant for HBsAg.


Cite this article:
Mohammed M. Safhi, S.M. Sivakumar, Aamena Jabeen, N.Sukumaran. Preparation and In vitro evaluation of HBsAg loaded Dextran microparticles. Research J. Pharm. and Tech. 7(10): Oct. 2014 Page 1137-1139.

Cite(Electronic):
Mohammed M. Safhi, S.M. Sivakumar, Aamena Jabeen, N.Sukumaran. Preparation and In vitro evaluation of HBsAg loaded Dextran microparticles. Research J. Pharm. and Tech. 7(10): Oct. 2014 Page 1137-1139.   Available on: https://rjptonline.org/AbstractView.aspx?PID=2014-7-10-26


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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