Author(s): Yarnykh T. G., Kotvitska A. A., Tykhonov A. I., Rukhmakova O. A.

Email(s): rukhmakovaolga@gmail.com

DOI: 10.5958/0974-360X.2020.00614.9   

Address: Yarnykh T. G.1, Kotvitska A. A.2, Tykhonov A. I.3, Rukhmakova O. A.4*
1Doctor of Pharmacy, Professor, Head of Drugs Technology Department, NUPh, Ukraine.
2Doctor of Pharmacy, Professor, Rector of NUPh, Ukraine.
3Doctor of Pharmacy, Professor, Professor of Cosmetology and Aromology Department, NUPh, Ukraine.
4Doctor of Pharmacy, Associate Professor, Associate Professor of Drugs Technology Department, NUPh, Ukraine.
*Corresponding Author

Published In:   Volume - 13,      Issue - 7,     Year - 2020


ABSTRACT:
The objective of the work – is to study and analyze causes of incompatibilities, their types and ways of overcoming in extemporaneous prescriptions based on data from literary sources. In the work, the retrospective, logical, and analytical research methods have been used to analyze the data of special literature. Based on the data of modern scientific literature, causes of pharmaceutical incompatibilities, their types and major ways of overcoming in extemporaneous prescriptions have been studied and analyzed. The given information of the problem of pharmaceutical incompatibilities, in our opinion, will increase the professional knowledge of pharmacists about the physical phenomena and chemical interactions that may occur in dosage forms, types of pharmacological incompatibilities and will guide them in practical activities in preparation of extemporaneous medicines in different dosage forms.


Cite this article:
Yarnykh T. G., Kotvitska A. A., Tykhonov A. I., Rukhmakova O. A. Pharmaceutical Incompatibilities: Causes, Types and Major ways of Overcoming in Extemporaneous Medicinal forms. Research J. Pharm. and Tech. 2020; 13(7): 3459-3465. doi: 10.5958/0974-360X.2020.00614.9


REFERENCES:
1. Bentley J, Heard J, Collins G, Chung C. Mixing medicines: how to ensure patient safety. Pharmac J. 2015;294(7859).
2. Dash A, Singh S, Tolman J. Pharmaceutics: Basic Principles and Application to Pharmacy Practice. USA: Academic Press; 2013. p. 392.
3. Elliott M, Liu Y. The nine rights of medication administration: an overview. Br J Nurs. 2010;19(5):300-5.
4. FIP. Reference guide on Good Pharmacy Practice in community and hospital settings. First edition, 2009. – https://www.fip.org/www/uploads/database_file.php?id=331&table_id=
5. Joint FIP/WHO guidelines on good pharmacy practice. WHO Technical Report Series, No. 961, 2011. Geneva: WHO, 2011. http://apps.who.int/medicinedocs/en/m/abstract/Js18676en/
6. Kanji S, Lam J, Johanson C, et al. Systematic review of compatibility of commonly used medications administered by continuous infusion. Crit Care Med. 2010;38(9):1890-8.
7. Klopotowska JE, Kuiper R, van Kan HJ, et al. On-ward participation of a hospital pharmacist in a Dutch intensive care unit reduces errors and related harm. Crit Care. 2010;14(5):R174.
8. Newton D. Drug incompatibility chemistry. Am J Health Syst Pharm. 2009;66(4):348-57. Erratum in Am J Health Syst Pharm. 2009;66(16):1431.
9. Perez M, Décaudin B, Foinard A, et al. Compatibility of medications during multi-infusion therapy: a controlled study on a infusion device. Anaesth Crit Care Pain Med. 2015;34(2):83-8.
10. Pharmaceutical Stability. USP Pharmacists’ Pharmacopeia. 2nd ed. Rockville: The United State Pharmacopeia; 2008. p. 922-3.
11. Qiu Y, Chen Y, Zhang GG, Yu L, Mantri RV. Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice. 2nd ed. New York: Academic Press; 2016. p. 1176.
12. Rothschild JM, Churchill W, Erickson A, et al. Medication errors recovered by emergency department pharmacists. Ann Emerg Med. 2010;55(6):513-21.
13. Stability Considerations in Dispensing Practice. USP Pharmacists’ Pharmacopeia. 2nd ed. Rockville: The United State Pharmacopeia; 2008. p. 957-60.
14. The Order of the Ministry of Health of Ukraine "On the WHO and FIP Guidelines" Proper Pharmacy Practice: Pharmacy Quality Standards: http://zakon.nau.ua/doc/?uid=1039.12816.0
15. Trissel LA. Handbook on injectable drugs. 17th ed. Maryland: American Society of Health- System Pharmacists; 2013.
16. Tykhonov OI, Yarnykh TH, Hrytsenko IS, Khokhlenkova NV. Extemporal Formulation (Technology, Analysis, Application): Methodical recommendations. Кyiv: Publishing House Agency of Medical Marketing; 2016. p. 352.
17. Tykhonov OI, Yarnykh TH. Pharmacy Technology of Drugs. Nova Knyha: Vinnytsia Ukraine; 2016. p. 536.

Recomonded Articles:

Author(s): Niharika, Navneet Verma

DOI: 10.5958/0974-360X.2016.00182.7         Access: Open Access Read More

Author(s): Ravindranath S. Misal, Vishawas R. Potphode, Vijay R. Mahajan

DOI: 10.5958/0974-360X.2017.00218.9         Access: Open Access Read More

Author(s): Koushika Das, Pranit Krishna, Avipsha Sarkar, Shanmuga Sundari Ilangovan, Shampa Sen

DOI: 10.5958/0974-360X.2017.00267.0         Access: Open Access Read More

Author(s): U.S Mahadeva Rao, Khamsah Suryati Mohd, Abdurrazaq Muhammad, Bashir Ado Ahmad, Mohaslinda Mohamad, Rosmawati Mat Ali

DOI: Not Available         Access: Open Access Read More

Author(s): A. Julius, Ramachandran Vedasendiyar, Archana Devakannan, Sujatha Rajaraman, Balamurugan Rangasamy, V. Saravanan

DOI: 10.5958/0974-360X.2017.00062.2         Access: Open Access Read More

Author(s): Archana Kushwaha, Jayanti Jaiswal, Priya Singh, Neha Rathore, Jai Prakash Dhruw, Ishu Sahu, Chhaya Singh, Krinsha Kumar Sahu, Mukta Agrawal, D. K. Tripathi, Ajazuddin, Amit Alexander

DOI: 10.5958/0974-360X.2017.00270.0         Access: Open Access Read More

Author(s): T. Arunkumar, Ann Feba Ebby, G. Narendrakumar

DOI: 10.5958/0974-360X.2017.00441.3         Access: Open Access Read More

Author(s): Avinash Bhagwat, Suhas M Kakade, Chirag V Naval, Mukesh Tilker, Ravindra M Walture, Sagar A Adichwal and Atul P Chaudhari

DOI: Not Available         Access: Open Access Read More

Author(s): Kousalya M., Geetha P., Jesuraja A., Vinoth Kumar M

DOI: 10.5958/0974-360X.2017.00014.2         Access: Open Access Read More

Author(s): Ahmed Hilal Sheriff, Preetham Prasad Nittla

DOI: 10.5958/0974-360X.2019.00968.5         Access: Open Access Read More

Author(s): Narendra Chotai, Vishnu Patel, Harsha Patel, Uren Patel, Rajendra Kotadiya

DOI:         Access: Open Access Read More

Author(s): Homendra Kumar Sahu, Kamdev Sen, Raju Patel, Hulash Sahu, Deepika Sahu, Gulshan Sahu, Chandrashekhar Jain, Narayan Prasad Chandra, Mukta Agrawal, D. K. Tripathi, Ajazuddin, Amit Alexander

DOI: 10.5958/0974-360X.2017.00173.1         Access: Open Access Read More

Author(s): M. A. Fazeelath Banu, Karthikeyan Murthykumar, Dr. Dhanraj

DOI: 10.5958/0974-360X.2016.00184.0         Access: Open Access Read More

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags