Author(s):
Yogesh Kumar Gupta, Vinita Gupta
Email(s):
ykgbkbiet123@gmail.com , yk.gupta@bkbiet.ac.in
DOI:
10.52711/0974-360X.2026.00602 
Address:
Yogesh Kumar Gupta1*, Vinita Gupta2
1Professor in Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, India.
2Professor in Chemistry, Agra College Agra, U.P.
*Corresponding Author
Published In:
Volume - 19,
Issue - 9,
Year - 2026
ABSTRACT:
A series of nitrogen and sulphur donor Schiff base ligands derived from salicylaldehyde and thiosemicarbazone were synthesized and characterized. Their transition metal complexes with Cu (II), Ni (II), Co (II), and Zn (II) ions were prepared under reflux conditions and studied using elemental analysis, molar conductance, magnetic susceptibility, FT-IR, UV-Visible spectroscopy, thermal analysis, and X-ray diffraction data reported in recent literature. The synthesized ligands behaved as bidentate N, S donor systems coordinating through azomethine nitrogen and thiocarbonyl sulphur atoms. Physico-chemical investigations revealed octahedral geometries for Co (II) and Ni (II) complexes, distorted octahedral geometry for Cu (II), and tetrahedral geometry for Zn (II). Antimicrobial screening demonstrated enhanced biological activity of metal complexes compared with free ligands due to chelation effects. The study confirms that mixed donor ligands provide stable coordination frameworks with promising catalytic and biological applications.
Cite this article:
Yogesh Kumar Gupta, Vinita Gupta. Synthesis, Characterization and Physico-Chemical studies of some Nitrogen and Sulphur Donor Ligands and Their Transition Metal Complexes. Research Journal Pharmacy and Technology. 2026;19(9):4319-1. doi: 10.52711/0974-360X.2026.00602
Cite(Electronic):
Yogesh Kumar Gupta, Vinita Gupta. Synthesis, Characterization and Physico-Chemical studies of some Nitrogen and Sulphur Donor Ligands and Their Transition Metal Complexes. Research Journal Pharmacy and Technology. 2026;19(9):4319-1. doi: 10.52711/0974-360X.2026.00602 Available on: https://rjptonline.org/AbstractView.aspx?PID=2026-19-9-48
7. REFERENCES:
1. Parkash J. Schiff base ligand system containing ONO donor atoms and synthesis of metal complexes by direct and template methods. J Chem Health Risks. 2024; 14(6): 2734-2746.
2. Inorganics Kótai L. Metal complexes with N-donor ligands. Inorganics. 2025; 13(11): 376-381.
3. Kumar M, Singh AK, Singh VK, Yadav RK, Singh AP, Singh S. Recent developments in the biological activities of 3d-metal complexes with salicylaldehyde-based N, O-donor Schiff base ligands. Coord Chem Rev. 2024.
4. Shotonwa IO, Oduwole AP, Agosu OM, Yusuf AF, Eze SO. Single and mixed dithiocarbamato metal (III) complexes (Co, Rh, and Ir): crystal and molecular structure description and interplay. Eur J Chem. 2024; 15(3): 291-301.
5. Kainat SF, et al. Recent developments in the synthesis and applications of terpyridine-based metal complexes: a systematic review. RSC Adv. 2024; 14(30): 21464-21468.
6. Zou M, Waldie KM. Redox-active ligand promoted multielectron reactivity at earth-abundant transition metal complexes. Inorg Chem Front. 2024; 11(18): 5795-5809.
7. Titova Y. Transition metal complexes with amino acids, peptides and carbohydrates in catalytic asymmetric synthesis: a short review. Processes. 2024; 12(1): 214-219.
8. Hendi Z, Pandey MK, Kushvaha SK, Roesky HW. Recent progress in transition metal complexes featuring silylene as ligands. Chem Commun. 2024; 60(71): 9483-9488.