Author(s):
Ajay I. Patel, Khushali R Patel, Darshita R Vyas, Amitkumar J. Vyas, Ashvin V Dudhrejiya, Sunny R Shah, Devang B Sheth, Sandip P Dholkia, Hetal B Gavit
Email(s):
khushalipatel0408@gmail.com
DOI:
10.52711/0974-360X.2026.00589 
Address:
Ajay I. Patel1, Khushali R Patel1*, Darshita R Vyas1 , Amitkumar J. Vyas1, Ashvin V Dudhrejiya1, Sunny R Shah2, Devang B Sheth3, Sandip P Dholkia3, Hetal B Gavit1
1B. K. Mody Government Pharmacy College, Rajkot, 360003, Gujarat, India.
2Government Pharmacy College, Gandhinagar, Gujarat, India.
3L. M. College of Pharmacy, Navrangpura, Ahmedabad - 380009.
*Corresponding Author
Published In:
Volume - 19,
Issue - 9,
Year - 2026
ABSTRACT:
This present work aimed to develop a simple, accurate, precise, and reproducible Stability Indicating RP-HPLC method for the simultaneous determination of Silodosin and Solifenacin Succinate Separation was achieved by chromatographic condition XTerra Phenyl (250mm x 4.6mm, 5µm) column with the mobile phase composition [Buffer: Acetonitrile (60:40 %v/v)]. Potassium Dihydrogen Phosphate buffer (pH 6) was used as the buffer. The injection volume was set to 10µL. The detection was carried out at 220nm with a 1.0mL/min flow rate. Silodosin and Solifenacin Succinate were eluted with retention times of 4.4min and 6.3min respectively. The result revealed that the developed method is suitable for routine analysis of determining Silodosin and Solifenacin Succinate in a synthetic mixture.
Cite this article:
Ajay I. Patel, Khushali R Patel, Darshita R Vyas, Amitkumar J. Vyas, Ashvin V Dudhrejiya, Sunny R Shah, Devang B Sheth, Sandip P Dholkia, Hetal B Gavit. Stability Indicating RP-HPLC Method for Simultaneous Estimation of Silodosin and Solifenacin Succinate for Treatment Benign Prostate Hyperplasia. Research Journal Pharmacy and Technology. 2026;19(9):4218-2. doi: 10.52711/0974-360X.2026.00589
Cite(Electronic):
Ajay I. Patel, Khushali R Patel, Darshita R Vyas, Amitkumar J. Vyas, Ashvin V Dudhrejiya, Sunny R Shah, Devang B Sheth, Sandip P Dholkia, Hetal B Gavit. Stability Indicating RP-HPLC Method for Simultaneous Estimation of Silodosin and Solifenacin Succinate for Treatment Benign Prostate Hyperplasia. Research Journal Pharmacy and Technology. 2026;19(9):4218-2. doi: 10.52711/0974-360X.2026.00589 Available on: https://rjptonline.org/AbstractView.aspx?PID=2026-19-9-35
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