Author(s):
Nour Athiroh A.S., Mahanem Mat Noor, Erna Sulistyowati
Email(s):
dr_erna@unisma.ac.id
DOI:
10.52711/0974-360X.2026.00517 
Address:
Nour Athiroh A.S.1, Mahanem Mat Noor2, Erna Sulistyowati3,4*
1Faculty of Mathematics and Natural Sciences, Universitas Islam Malang, Malang 65144, Indonesia.
2Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan, Malaysia, Bangi, Selangor 43600 Malaysia.
3Faculty of Medicine, Universitas Islam Malang, Malang 65144, Indonesia.
4Center for the Integration of Islamic Medicine, Bioinformatics and Indonesian Traditional Medicine.
*Corresponding Author
Published In:
Volume - 19,
Issue - 8,
Year - 2026
ABSTRACT:
The combined extract of Scurrula atropurpurea BI. Dans (SA) leaves and Dendrophthoe petandra (DP) leaves contains phytoactive substances that have the potential to maintain health, including reducing blood pressure. This study was to observe the safety of SADP combination to healthy human subjects. 35 healthy subjects participated in the single-blind randomized clinical trial. The control (placebo) group was compared with the intervention group, who received oral 560 mg of SA and 187 mg of DP, which were consumed in 3 capsules a day for 15 days. Consumption of SADP provided no side effects on healthy subjects. The vital signs (blood pressure, pulse, and respiratory rate), routine blood tests, serum profiles such as kidney function (urea, creatinine), liver function (AST and ALT), and lipid profile (total cholesterol, triglyceride, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol) showed normal results, like the control group. It can be concluded that oral administration of SADP capsules has beneficial effects on healthy subjects and does not cause harmful side effects.
Cite this article:
Nour Athiroh A.S., Mahanem Mat Noor, Erna Sulistyowati. The Effects of Oral Administration of Scurrula atropurpurea BI. Dans and Dendrophthoe petandra Leaves in Healthy Subjects: A First phase Clinical Trial. Research Journal of Pharmacy and Technology. 2026;19(8):3665-0. doi: 10.52711/0974-360X.2026.00517
Cite(Electronic):
Nour Athiroh A.S., Mahanem Mat Noor, Erna Sulistyowati. The Effects of Oral Administration of Scurrula atropurpurea BI. Dans and Dendrophthoe petandra Leaves in Healthy Subjects: A First phase Clinical Trial. Research Journal of Pharmacy and Technology. 2026;19(8):3665-0. doi: 10.52711/0974-360X.2026.00517 Available on: https://rjptonline.org/AbstractView.aspx?PID=2026-19-8-34
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