Author(s):
Shweta Manchanda, Yamini Sharma, Vishal Sareen, Jyoti Singh, Ketan Patil, Ranjan Mitra
Email(s):
ranjan.mitra@dabur.com
DOI:
10.52711/0974-360X.2026.00362 
Address:
Shweta Manchanda, Yamini Sharma, Vishal Sareen, Jyoti Singh, Ketan Patil, Ranjan Mitra*
Department of Research and Development Centre (DRDC), Dabur India Ltd., 22, Site IV, Sahibabad, Ghaziabad - 201010, Uttar Pradesh (UP), India.
*Corresponding Author
Published In:
Volume - 19,
Issue - 6,
Year - 2026
ABSTRACT:
Salt-based herbal dentifrices combine the abrasive cleansing action of salt with bioactive plant constituents. In this work, we profiled the antioxidant capacity and phytochemical composition of salt-based herbal toothpaste, ayurvedic toothpaste and salt-based toothpaste, focusing on the flavor-active markers like camphor, menthol, eugenol, and piperine. These were quantified by validated GC-FID (Gas Chromatography with Flame Ionization Detector) and HPLC (High performance Liquid Chromatography) protocols. Free-radical scavenging potential was determined via the DPPH assay (reported as Trolox Equivalent Antioxidant Capacity, TEAC) and salt content was measured titrimetrically. Across the formulations tested, salt-based herbal toothpaste displayed the most robust antioxidant response and the most complex phytochemical signature, suggesting a contribution from both mineral and botanical components. These findings provide laboratory evidence in support of traditional herbal-salt dentifrices and illustrate how analytical characterization can substantiate their functional claims.
Cite this article:
Shweta Manchanda, Yamini Sharma, Vishal Sareen, Jyoti Singh, Ketan Patil, Ranjan Mitra. Research Journal Pharmacy and Technology. 2026;19(6):2531-4. doi: 10.52711/0974-360X.2026.00362
Cite(Electronic):
Shweta Manchanda, Yamini Sharma, Vishal Sareen, Jyoti Singh, Ketan Patil, Ranjan Mitra. Research Journal Pharmacy and Technology. 2026;19(6):2531-4. doi: 10.52711/0974-360X.2026.00362 Available on: https://rjptonline.org/AbstractView.aspx?PID=2026-19-6-19
REFERENCES:
1. Janakiram C et al. Effectiveness of herbal oral care products in reducing dental plaque and gingivitis: a systematic review and meta-analysis. BMC Complement Med Ther. 2020; 20: 43. doi:10.1186/s12906-020-2812-1.
2. Nagansurkar SB et al. Preparation and evaluation of herbal toothpaste. Int J Adv Res Sci Commun Technol. pp. 222–233. doi:10.48175/ijarsct-8094.
3. Bangar PK, Shelke DS. Formulation and evaluation of herbal toothpaste. Int J Adv Res Sci Commun Technol. 2022; 2(2). doi:10.48175/568.
4. Mangilal T, Ravikumar M. Preparation and evaluation of herbal toothpaste and comparison with commercial herbal toothpaste: an in vitro study. Int J Ayurvedic Herb Med. 2016; 6(3): 2266–2273.
5. Girija ASS et al. Investigation on the antioxidant, antibacterial and antibiofilm properties of three distinct herbal tooth powders. BOHR Int J Curr Res Dent. 2023; 2(1): 22–28. doi:10.54646/bijcrid.2023.14.
6. Deshmukh P, Shende V, Gunde M. Formulation and evaluation of herbal toothpaste. Int J Pharm Drug Anal. 2017.
7. Davies R, Scully C, Preston AJ. Dentifrices: an update. Med Oral Patol Oral Cir Bucal. 2010; 15: 976–982.
8. KCC College. JIGYAASA Vol V Issue II [Internet]. 2024. Available from: https://kccollege.edu.in/wp-content/uploads/2024/05/JIGYAASA-VOL-V-Issue-II.pdf
9. Rajale PA, Gaikwad VA. A review on herbal toothpaste. J Emerg Technol Innov Res. 2024; 11(6).
10. Baliyan S et al. Determination of antioxidants by DPPH radical scavenging activity and quantitative phytochemical analysis of Ficus religiosa. Molecules. 2022; 27: 1326.
11. Food Safety and Standards Authority of India. Manual of methods of analysis of foods: fruits and vegetables [Internet]. 2016. Available from: https://fssai.gov.in/upload/uploadfiles/files/Manual_Fruits_Veg_25_05_2016(1).pdf