Author(s):
Daya L. Chothani, Dipen Bhimani, Ashvin Dudhrejiya, Dipti Gohil, Rajesh A. Maheshwari, Kinjal Patel, Rahul Trivedi
Email(s):
daya.herb@gmail.com
DOI:
10.52711/0974-360X.2026.00225 
Address:
Daya L. Chothani1*, Dipen Bhimani1, Ashvin Dudhrejiya1, Dipti Gohil2, Rajesh A. Maheshwari2, Kinjal Patel2, Rahul Trivedi2
1Department of Pharmacy, B. K Mody Government Pharmacy College, Rajkot-360003, Gujarat, India.
2Department of Pharmacy, Sumandeep Vidyapeeth Deemed University, Piparia, Vadodara-391760, Gujarat.
*Corresponding Author
Published In:
Volume - 19,
Issue - 4,
Year - 2026
ABSTRACT:
The current study aims to assess the antioxidant properties of Ceropegia bulbosa var. lushii (Asclepiadaceae) utilizing in vitro models, specifically 2, 2-diphenyl-1-picrilhydrazyl (DPPH) radical scavenging activity, super oxide anion radical scavenging assay, and hydroxyl radical scavenging assay. Moreover, the total phenol and total flavonoid content were assessed using Folin-Ciocalteau reagent and colorimetric techniques with aluminum chloride respectively. Protein, carbohydrates, alkaloids, phenolic and flavonoid compounds were found in the preliminary phytochemical screening. The outcomes demonstrated that the extract from C. bulbosa tuber demonstrated DPPH radical scavenging action, with an IC50 value of 167.32± 3 µg/mL, in contrast to the standard ascorbic acid's 122.87±1.448 µg/mL. The extract's IC50 value for the super oxide anion radical scavenging activity was 1.75 ± 0.14 mg/ml, while the IC50 value for the hydroxyl free radical scavenging assay was 125± 0.085µg/ml) compared to the standard Gallic acid (IC50 = 2.999± 0.082µg/ml). The total phenolic and total flavonoid contents were reported as 53.33± 0.58 µg/mg extract and 141.66± 3.8µg/mg extract, respectively. With respect to the standard, the aqueous extract revealed a notable level of antioxidant activity. It has been revealed that the Ceropegia bulbosa tuber displays antioxidant activity. The additional research could be done to figure out the active principle producing this effect.
Cite this article:
Daya L. Chothani, Dipen Bhimani, Ashvin Dudhrejiya, Dipti Gohil, Rajesh A. Maheshwari, Kinjal Patel, Rahul Trivedi. Assessment of Total Phenolic, Total Flavonoid and In Vitro Anti-Oxidant Potential of Water Extract of Ceropegia bulbosa var. Lushii (graham) hook. f. Tuber. Research Journal of Pharmacy and Technology. 2026;19(4):1577-3. doi: 10.52711/0974-360X.2026.00225
Cite(Electronic):
Daya L. Chothani, Dipen Bhimani, Ashvin Dudhrejiya, Dipti Gohil, Rajesh A. Maheshwari, Kinjal Patel, Rahul Trivedi. Assessment of Total Phenolic, Total Flavonoid and In Vitro Anti-Oxidant Potential of Water Extract of Ceropegia bulbosa var. Lushii (graham) hook. f. Tuber. Research Journal of Pharmacy and Technology. 2026;19(4):1577-3. doi: 10.52711/0974-360X.2026.00225 Available on: https://rjptonline.org/AbstractView.aspx?PID=2026-19-4-14
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