Author(s):
Shubham Gulhane, Aastha Padawe, Nisha Varandani, Ankita Gawande, Yuganti Belsare, Dipti Bonde, Pankaj Khawale, Shivprasad Chilkar, Rupali Gawande, Pragati Katkide
Email(s):
pdshubhamgulhane@gmail.com
DOI:
10.52711/0974-360X.2026.00148 
Address:
Shubham Gulhane1*, Aastha Padawe1, Nisha Varandani1, Ankita Gawande1, Yuganti Belsare1, Dipti Bonde1, Pankaj Khawale1, Shivprasad Chilkar2, Rupali Gawande1, Pragati Katkide1
1Department of Pharmacy, P.R. Pote Patil College of Pharmacy, Amravati – 444602.
2Senior officer at USV Pvt Ltd.
*Corresponding Author
Published In:
Volume - 19,
Issue - 3,
Year - 2026
ABSTRACT:
Chloroxylon swietenia has long been utilized in traditional medicine as an antibiotic, antifertility, analgesic, insecticidal, and antifeedant. The current study aims to assess the hepatoprotective activity of Chloroxylon swietenia leaf extract against carbon tetrachloride-induced hepatotoxicity in rats. The Chloroxylonswietenia ethanolic extract used, its hepatoprotective activity was assessed through qualitative screening. hepatoprotective activity compared with standard hepatoprotective drug (liv 52 syrup). Rats treated with CCl4 and then given 250 mg/kg of Chloroxylonswietenia leaves ethanolic extract and fractions showed nearly normal architecture of their liver tissues, which suggests that the extract and fractions have hepatoprotective properties. This result was comparable to that of using a popular Liv 52 syrup. Rats' livers tissue to be protected by an ethanolic extract of Chloroxylonswietenia leaves. During the 48-hour trial period, the rats showed no signs of toxicity or death.
Cite this article:
Shubham Gulhane, Aastha Padawe, Nisha Varandani, Ankita Gawande, Yuganti Belsare, Dipti Bonde, Pankaj Khawale, Shivprasad Chilkar, Rupali Gawande, Pragati Katkide. Assessment of Chloroxylon Swietenia's Hepatoprotective Potential in Relation To Toxicity in Rats. Research Journal Pharmacy and Technology. 2026;19(3):1047-2. doi: 10.52711/0974-360X.2026.00148
Cite(Electronic):
Shubham Gulhane, Aastha Padawe, Nisha Varandani, Ankita Gawande, Yuganti Belsare, Dipti Bonde, Pankaj Khawale, Shivprasad Chilkar, Rupali Gawande, Pragati Katkide. Assessment of Chloroxylon Swietenia's Hepatoprotective Potential in Relation To Toxicity in Rats. Research Journal Pharmacy and Technology. 2026;19(3):1047-2. doi: 10.52711/0974-360X.2026.00148 Available on: https://rjptonline.org/AbstractView.aspx?PID=2026-19-3-9
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