Author(s):
Anitha Nandagopal, Nemala Appala Raju, Anupama Koneru
Email(s):
rajnemala@sucp.ac.in
DOI:
10.52711/0974-360X.2026.00052 
Address:
Anitha Nandagopal1, Nemala Appala Raju2*, Anupama Koneru3
1Department of Pharmacology, Sultan-ul-Uloom College of Pharmacy, Road no.3, Banjara Hills, Hyderabad-500034, Telangana, India.
2Department of Pharmacognosy, Sultan-ul-Uloom College of Pharmacy, Road no.3, Banjara Hills, Hyderabad-500034, Telangana, India.
3Department of Pharmacology, Sultan-ul-Uloom College of Pharmacy, Road no.3, Banjara Hills, Hyderabad-500034, Telangana, India.
*Corresponding Author
Published In:
Volume - 19,
Issue - 1,
Year - 2026
ABSTRACT:
Ethoxy Analogue of Curcumin (EAC) is a compound with various therapeutic benefits but suffers from low bioavailability due to poor water solubility and rapid metabolism. Buccal films, which swell up to 80% when hydrated by saliva, offer a solution to enhance EAC's solubility and absorption. This study evaluated the effect of different polymer concentrations in buccal films on EAC release, using solid dispersion and solvent casting methods. Polyethylene oxide (PEO) showed the best release profile compared to pectin and hyaluronic acid, with higher polymer concentrations reducing release rates. The findings underscore buccal films' potential to improve EAC bioavailability, with polymer concentration being key to optimizing release.
Cite this article:
Anitha Nandagopal, Nemala Appala Raju, Anupama Koneru. Effect of Polymer Concentrations on Buccal Film Delivery Systems for Ethoxy Curcumin Analogue (EAC). Research Journal of Pharmacy and Technology. 2026;19(1):358-3. doi: 10.52711/0974-360X.2026.00052
Cite(Electronic):
Anitha Nandagopal, Nemala Appala Raju, Anupama Koneru. Effect of Polymer Concentrations on Buccal Film Delivery Systems for Ethoxy Curcumin Analogue (EAC). Research Journal of Pharmacy and Technology. 2026;19(1):358-3. doi: 10.52711/0974-360X.2026.00052 Available on: https://rjptonline.org/AbstractView.aspx?PID=2026-19-1-52
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