Author(s):
Ranjeet Kaur Parmar, Amandeep Kaur Gill, Vinay Thakur
Email(s):
amansatnamgill@gmail.com
DOI:
10.52711/0974-360X.2025.00661 
Address:
Ranjeet Kaur Parmar1, Amandeep Kaur Gill1*, Vinay Thakur2
1School of Pharmaceutical Sciences, CT University, Ludhiana, Punjab, 142024, India.
2Department of Pharmaceutical Sciences, Government Pharmacy College, Kangra at Nagrota Bagwan, Himachal Pradesh -176047, India.
*Corresponding Author
Published In:
Volume - 18,
Issue - 9,
Year - 2025
ABSTRACT:
The engaging and fragrant blossoms of Buddleja led researchers to exploit them commercially in ornamental gardens and landscaping. Buddlejas are widely used in the horticultural business and are marketable plants, several robust and innovative hybrids have been created to highlight their economic worth. Due to their utility in decorative landscaping, numerous hybridization and breeding programs have been carried out globally to produce distinct, novel, and patentable plant cultivars. In addition to being utilized in horticulture and ecology, they have been used ethnopharmacologically for various illnesses. This article is the first of its kind highlighting the applications of Buddleja in hybridization, patenting, and therapeutics.
Cite this article:
Ranjeet Kaur Parmar, Amandeep Kaur Gill, Vinay Thakur. Hybridization, Patenting and Therapeutic Facets of Buddleja. Research Journal of Pharmacy and Technology. 2025;18(9):4603-6. doi: 10.52711/0974-360X.2025.00661
Cite(Electronic):
Ranjeet Kaur Parmar, Amandeep Kaur Gill, Vinay Thakur. Hybridization, Patenting and Therapeutic Facets of Buddleja. Research Journal of Pharmacy and Technology. 2025;18(9):4603-6. doi: 10.52711/0974-360X.2025.00661 Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-9-81
REFERENCES:
1. Tallent-Halsell NG, Watt MS. The invasive Buddleja davidii (butterfly bush). The Botanical Review. 2009; 75: 292-325.
2. Zhang J. Hybridization and Cutting of Buddleja Genus. In E3S Web of Conferences. EDP Sciences. 2020; 145: 01010.
3. Lehner S, Schulz S, Dotterl S. The mystery of the butterfly bush Buddleja davidii: How are the butterflies attracted? Frontiers in Plant Science. 2022; 13:994851.
4. Katiyar C, Gupta A, Kanjilal S, Katiyar S. Drug discovery from plant sources: An integrated approach. AYU. 2012; 33(1): 10-9.
5. Khan S, Ullah H, Zhang L. Bioactive constituents form Buddleja species. Pakistan Journal of Pharmaceutical Sciences. 2019; 32(2).
6. Goulet BE, Roda F, Hopkins R. Hybridization in plants: old ideas, new techniques. Plant Physiology. 2017; 173(1): 65-78.
7. Soltis PS, Soltis DE. The role of hybridization in plant speciation. Annual review of Plant Biology. 2009; 60: 561-88.
8. Liao R, Sun W, Ma Y. Natural hybridization between two butterfly bushes in Tibet: dominance of F 1 hybrids promotes strong reproductive isolation. BMC Plant Biology. 2021; 21: 1-5.
9. Laere KV, Huylenbroeck JV, Bockstaele EV. Introgression of yellow flower color in Buddleja davidii by means of polyploidization and interspecific hybridization. Hort. Sci. (Prague). 2011; 38(3): 96–103.
10. Lindstrom JT, Bujarski GT, Burkett BM. A novel intersectional Buddleja hybrid. Hort. Science. 2004; 39(3): 642-643.
11. Gong WC, Chen YQ, Wang J, Yuan H. Effects of hybridization on the determinants of photosynthetic capacity in Buddleja F1 hybrids. Photosynthetica. 2020; 58(4).
12. Elliott W, Werner DJ, Fantz PR. A Hybrid of Buddleja davidii var. nanhoensis Nanho Purple' and B. lindleyana. Hort. Science. 2004; 39(7): 1581-3.
13. Available on https://patents.justia.com. Accessed on 20 Feb. 2024.
14. Podaras P. United States patent Application No. 17/978,395. 2004.
15. Hansen HA. United States patent Application No. 17/803,928. 2003
16. Podaras P. United States patent Application No. 17/978,414. 2023.
17. Valin C. United States patent Application No. 17/849,791. 2023.
18. Koot JAM. United States Patent Application No. 17/557,043. 2022.
19. Koot JAM. United States patent Application No. 17/557,032. 2022.
20. Koot JAM. United States patent Application No. 17/556,969. 2022.
21. Koot JAM. United States patent Application No. 17/557,039. 2022.
22. Koot JAM. United States patent Application No. 17/557,177. 2022.
23. Werner DJ. United States patent Application No. 14/756,094. 2017.
24. Werner DJ. United States patent Application No. 14/545,797. 2017.
25. Hansen HA. United States patent Application No. 14/999,593. 2017.
26. Hansen HA. United States patent Application No. 14/999,590. 2017.
27. Hansen HA. United States patent Application No. 14/999,589. 2017.
28. Brand MH & Smith WA. United States patent Application No. 14/545,698. 2017.
29. Brand MH & Smith WA. United States patent Application No. 14/545,688. 2017.
30. Werner DJ. United States patent Application No. 13/999,798. 2017.
31. Werner DJ. United States patent Application No. 13/999,799. 2015.
32. Werner DJ. & Snelling LK. United States patent Application No. 12/931,038. 2014.
33. Werner DJ. & Snelling LK. United States patent Application No. 13/373,183. 2013.
34. Werner DJ. & Snelling LK. United States patent Application No. 13/373,181. 2013.
35. Werner DJ. & Snelling LK. United States patent Application No. 12/931,039. 2013.
36. Brand MH. & Smith WA. United States patent Application No. 12/804,186. 2012.
37. Moore P. United States patent Application No. 13/065,262. 2012.
38. Senior JR. United States patent Application No. 12/925,455. 2012.
39. Valin C. United States patent Application No. 12/807,073. 2011.
40. Podaras P. United States patent Application No. 12/660,674. 2011.
41. Bloom A. United States patent Application No. 12/151,755. 2009.
42. Werner DJ. & Snelling LK. United States patent Application No. 11/894,885. 2009.
43. Werner DJ. & Snelling LK. United States patent Application No. 11/894,866. 2009.
44. Moore P. United States patent Application No. 11/123,554. 2007.
45. Van Den Nest W, Serraima CC, Gonzalez RD, & Montiel AVF. United States patent Application No. 9,511,010. 2016.
46. Houghton PJ. Ethnopharmacology of some Buddleja species. Journal of Ethnopharmacology. 1984; 11(3):293-308.
47. Romeo JT, Phytochemicals in human health protection, nutrition, and plant defense. Springer Science & Business Media. 2012.
48. Ahmad I, Malik A, Afza N, Anis I, Fatima I, Nawaz SA, Tareen RB, Choudhary MI. Enzymes inhibitory constituents from Buddleja crispa. Zeitschrift für Naturforschung B. 2005; 60(3): 341-6.
49. Ahmad I, Ahmad N, Wang F. Antioxidant phenylpropanoid glycosides from Buddleja davidii. Journal of Enzyme Inhibition and Medicinal Chemistry. 2009; 24(4): 993-7.
50. Raja S, Ramya I. A review on ethnopharmacology, phytochemistry and pharmacology of Buddleja asiatica. International Journal of Pharmaceutical Sciences and Research. 2016; 7(12): 4697.
51. Haile F, Kifle ZD, Dejenie TA, Berhane N. Synergetic antibacterial activity of Vernonia auriculifera Hiern and Buddleja polystachya Fresen on selected human pathogenic bacteria. Metabolism Open. 2022; 16: 100210.