Author(s):
Rajalakshmi Shanmugavelan, Mohamed Musthafa M
Email(s):
dr.rajibsms23@gmail.com
DOI:
10.52711/0974-360X.2025.00439 
Address:
Rajalakshmi Shanmugavelan1*, Mohamed Musthafa M2
1Research Associate- III, Siddha Clinical Research Unit,
Under Central Council for Research in Siddha, Tirupati, Andhra Pradesh, India.
2Head of the Department, Department of Pura Maruthuvam, Government Siddha Medical College, Chennai, Tamil Nadu, India.
*Corresponding Author
Published In:
Volume - 18,
Issue - 7,
Year - 2025
ABSTRACT:
Background: Siddha system of medicine is a primordial system of medicine existed in the world and practiced in southern part of India. Siddhars are the spiritual scientists; they are well versed in Metallurgy, Geology and Phytochemistry, have used vastly all kinds of herbs, metals, minerals and animal products. Metals and minerals based formulations have good efficacy and potency than Botanicals in treating chronic ailments and they are generally made into preparation such as parpam, chendhuram, chunnam, pathangam, kattu, kalangu etc of which Chendhuram is more potent. But there is no standard operating procedure for the preparation of the above drugs. Materials and methods: The Siddha herbo-mineral formulation, PanchamugaChendhuram (PMC) cited in the ancient Siddha text Pulippani vaithyam-500 is recommended for various skin conditions, undergone physicochemical analysis, Fourier transform infrared spectrometer (FTIR), scanning electron Microscope (SEM) with Energy Dispersive X-ray (EDAX), Inductively Coupled Plasma Optical Emission spectroscopy(ICPOES) analysis to assess the safety and efficacy of this formulation. In this study PMC were assessed for quality control according to the standard guidelines for development of ASU drugs. Results: Physicochemical analysis shows that pH of PMC is 4.75, Loss on Drying (LOD) of PMC is 0.6. SEM analysis showed that on average the particle size ranges from 50nm- 500nm. Heavy metal and other constituents present in finished drug were identified. The ICPOES interpretation revealed that Hg, Pb, Cd, As are below detectable limit and As is only 0.09 ppm against the normal limits of 3 ppm, were within the WHO guidelines for assessing quality of herbal medicines. Conclusion: The elemental chemistry of finished drug obtained through this study may be a useful tool in standardization of drug (PMC).
Cite this article:
Rajalakshmi Shanmugavelan, Mohamed Musthafa M. Traditional Siddha Medicine: Panchamuga Chendhuram (PMC) Preparation and Standardization using Sophisticated Analytical Instrument. Research Journal of Pharmacy and Technology. 2025;18(7):3067-2. doi: 10.52711/0974-360X.2025.00439
Cite(Electronic):
Rajalakshmi Shanmugavelan, Mohamed Musthafa M. Traditional Siddha Medicine: Panchamuga Chendhuram (PMC) Preparation and Standardization using Sophisticated Analytical Instrument. Research Journal of Pharmacy and Technology. 2025;18(7):3067-2. doi: 10.52711/0974-360X.2025.00439 Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-7-19
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