Author(s):
Irfan Irfan, Nusratuddin Abdullah, Nasrudin A Mappaware, Suryani As’ad, Syamsuri Syakri
Email(s):
irfandokter@yahoo.com
DOI:
10.52711/0974-360X.2025.00401
Address:
Irfan Irfan1*, Nusratuddin Abdullah2, Nasrudin A Mappaware3, Suryani As’ad4,6, Syamsuri Syakri5
1Doctoral Program, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia, 90245, Indonesia.
2Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Hasanuddin, Makassar, 90245, Indonesia.
3Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Muslim Indonesia, Makassar, 90231, Indonesia.
4Department of Nutrition, Faculty of Medicine, Universitas Hasanuddin, Makassar, 90245, Indonesia
5Department of Pharmacy, Faculty of Medicine and Health Sciences, Universitas Islam Negeri Alauddin, Makassar, Indonesia.
6Medical Faculty and Health Sciences, Universitas Muhammadiyah Makassar, Makassar, Indonesia.
*Corresponding Author
Published In:
Volume - 18,
Issue - 6,
Year - 2025
ABSTRACT:
The Ajwa Dates (Phoenix dactylifera L) is one of the foods that can be consumed daily and has bioactive compounds that serve as fertilizers and other functions as therapies for various diseases and ajwa dates have compounds that are beneficial to human health. The purpose of this research is to do molecular docking of the ajwa dates compounds that are supposed to have affinities for anti-mullerian hormones. There are 15 Ajwa dates compounds that will do molecular docking with anti-mullerian receptors. Initial preparation of ligans and receptors by removing water molecules and other unnecessary residues will affect the docking outcome using Autodocktools and the Discovery Studio Visualizer. The docking results show that the caffeic acid compound is predicted to have the best affinity and activity for the receptor.
Cite this article:
Irfan Irfan, Nusratuddin Abdullah, Nasrudin A Mappaware, Suryani As’ad, Syamsuri Syakri. In silico Study of Secondary Metabolite Compounds in Ajwa Dates (Phoenix dactylifera L) as an Anti-Mullerian Hormone Theraphy: Molecular Docking Approach. Research Journal of Pharmacy and Technology. 2025;18(6):2803-7. doi: 10.52711/0974-360X.2025.00401
Cite(Electronic):
Irfan Irfan, Nusratuddin Abdullah, Nasrudin A Mappaware, Suryani As’ad, Syamsuri Syakri. In silico Study of Secondary Metabolite Compounds in Ajwa Dates (Phoenix dactylifera L) as an Anti-Mullerian Hormone Theraphy: Molecular Docking Approach. Research Journal of Pharmacy and Technology. 2025;18(6):2803-7. doi: 10.52711/0974-360X.2025.00401 Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-6-54
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