Author(s):
H. Damour, M. Oussekkour, I. Mahdad, Z. Mennane, S. El Hajjaji
Email(s):
h.damour@cnrst.ma
DOI:
10.52711/0974-360X.2025.00317 
Address:
H. Damour1,2*, M. Oussekkour3, I. Mahdad2, Z. Mennane4, S. El Hajjaji2
1Chemistry Department, National Center for Scientific and Technical Research, Mohammed V University, Rabat, Morocco,
2Laboratory of Molecular Spectroscopy Modelling, Materials, Nanomaterials, Water and Environment, CERNE2D, Faculty of Sciences, Mohammed V University in Rabat, Morocco
3National Office of Electricity and Drinking Water-Water Branch, Rabat, Morocco
4Department of Biology Faculty of Sciences Tetouan, Morocco
*Corresponding Author
Published In:
Volume - 18,
Issue - 5,
Year - 2025
ABSTRACT:
The Lamiaceae family, is renowned for the production of essential oils that are concentrated, volatile compounds responsible for the characteristic fragrance and various therapeutic properties of these plants contain a diverse array of aromatic compounds, including terpenes, phenols, aldehydes, and ketones. Many members of the Lamiaceae family contain specialized structures called glandular trichomes, which house and release these essential oils and Each plant species has a unique composition of essential oils, contributing to distinct fragrances and potential therapeutic effects. Aerial parts of Thymus vulgaris L., Lavandula angustifolia L., Salvia officinalis L. were subjected to hydrodistillation, and both resulting fractions were analyzed through GC-MS and Head-space GC-MS. The purpose of this study was to determine the chemical composition, antioxidant activity, and the antimicrobial activity against seven bacterial strains, Overall, 86 compounds were identified, some found exclusively in essential oils and others in hydrolats, making them individual products with specific end purposes.
Cite this article:
H. Damour, M. Oussekkour, I. Mahdad, Z. Mennane, S. El Hajjaji. Chemical investigation by GC-MS and Head-space and antimicrobial and antioxidant activity of Essential Oils and Their Corresponding Hydrolats from three Species of the Lamiaceae Family. Research Journal of Pharmacy and Technology. 2025;18(5):2213-9. doi: 10.52711/0974-360X.2025.00317
Cite(Electronic):
H. Damour, M. Oussekkour, I. Mahdad, Z. Mennane, S. El Hajjaji. Chemical investigation by GC-MS and Head-space and antimicrobial and antioxidant activity of Essential Oils and Their Corresponding Hydrolats from three Species of the Lamiaceae Family. Research Journal of Pharmacy and Technology. 2025;18(5):2213-9. doi: 10.52711/0974-360X.2025.00317 Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-5-40
REFERENCES:
1. S. Pradhan, S. Pattnaik. Phytochemical Screening of Components Present Floral Essential oil of an Indigenous Variety of Lantana camara, Linn (Verbenaceae). Res. J. Pharmacogn. Phytochem. 2017; 9: 203–209. https://doi.org/10.5958/0975-4385.2017.00037.1.
2. C. Madhu, J. Swapna, K. Neelima, M.V. Shah. A Comparative Evaluation of the Antioxidant Activity of Some Medicinal Plants Popularly Used in India. Asian J. Res. Pharm. Sci. 2012; 2: 98–100.
3. Mariyappan M., Bharathidasan R., Mahalingam R., Madhanraj P., Panneerselvam A. , Ambikapathy V. Antibacterial Activity of Cardiospermum halicacabum and Melothria heterophylla. Asian J. Pharm. Res. 2011; 1(4): 111-113.
4. M. Zohra, A. Fawzia. Chemical Composition and Antioxidant Activity of Essential Oil from Smyrnium olusatrum L. Asian J. Res. Chem. 2011; 4: 217–220.
5. Suganya S., Bharathidasan R., Senthilkumar G., Madhanraj P., Panneerselvam A. Antibacterial activity of essential oil extracted from Coriandrum sativam (L.) and GC-MS analysis. Research J. Science and Tech. 2012; 4(5): 203-207.
6. M. Shanaida. Determination of Triterpenoids in Some Lamiaceae Species. Res. J. Pharm. Technol. 2018; 11: 3113–3118. https://doi.org/10.5958/0974-360X.2018.00571.1.
7. P. Dongare, S. Dhande, V. Kadam. A Review on Pogostemon patchouli. Res. J. Pharmacogn. Phytochem. 2014; 6: 41–47.
8. R.K. Joshi. Essential oil composition of Thymus linearis (Benth) from western Himalaya of Uttrakhand, India. Asian J. Pharm. Technol. 2016; 6: 199–201. https://doi.org/10.5958/2231-5713.2016.00029.5.
9. R.M. Harfouch, M. Darwish, W. Al-Asadi, A.F. Mohammad, N.M. Gharib, M. Haroun. Antibacterial Activity of Essential Oils of Rosmarinus officinalis, Salvia officinalis and Anthemis nobilis Widespread in the Syrian Coast. Res. J. Pharm. Technol. 2019; 12: 3410–3412. https://doi.org/10.5958/0974-360X.2019.00576.6.
10. Punasiya R, Dindorkar G, Pillai S. Antibacterial and Antifungal Activity of Flower extract of Murraya paniculata L. Asian J. Res. Pharm. Sci. 2020; 10(1):17-20. doi: 10.5958/2231-5659.2020.00004.1
11. R. Malathi, S.A. John, A. Cholarajan. Antioxidant Activity of Extract from the Leaves of Tylophora asthmatica.Asian J. Res. Pharm. Sci. 2012; 2: 80–82.
12. H. Miladi, R.B. Slama, D. Mili, S. Zouari, A. Bakhrouf, E. Ammar. Essential oil of Thymus vulgaris L. and Rosmarinus officinalis L.: Gas chromatography-mass spectrometry analysis, cytotoxicity and antioxidant properties and antibacterial activities against foodborne pathogens. 2013 (2013). https://doi.org/10.4236/ns.2013.56090.
13. E. Mancini, F. Senatore, D. Del Monte, L. De Martino, D. Grulova, M. Scognamiglio, M. Snoussi, V. De Feo. Studies on Chemical Composition, Antimicrobial and Antioxidant Activities of Five Thymus vulgaris L. Essential Oils, Molecules. 2015; 20: 12016–12028. https://doi.org/10.3390/molecules200712016.
14. A. Gedikoğlu, M. Sökmen. A. Çivit. Evaluation of Thymus vulgaris and Thymbra spicata essential oils and plant extracts for chemical composition, antioxidant, and antimicrobial properties. Food Sci. Nutr. 2019; 7: 1704–1714. https://doi.org/10.1002/fsn3.1007.
15. S. Garzoli, V. Laghezza Masci, S. Franceschi, A. Tiezzi, P. Giacomello, E. Ovidi. Headspace/GC–MS analysis and investigation of antibacterial, antioxidant and cytotoxic activity of essential oils and hydrolates from Rosmarinus officinalis L. and Lavandula angustifolia Miller. Foods. 2021; 10: 1768.
16. M. Jeddi, N. El Hachlafi, M. El Fadili, N. Benkhaira, S. al-mijalli, F. Kandsi, E. Abdallah, Z. Ouaritini, A. Bouyahya, L.-H. Lee, G. Zengin, H. Naceiri Mrabti, K. Fikri Benbrahim. Antimicrobial, Antioxidant, α-Amylase and α-Glucosidase Inhibitory Activities of a chemically characterized Essential oil from Lavandula angustifolia Mill. In vitro and In silico investigations. Biochem. Syst. Ecol. 2023. https://doi.org/10.1016/j.bse.2023.104731.
17. A. Latreche, A. Rouibi, F. Saidi, Étude. Comparative DE LA Composition Chimique ET DE L’activité Antioxydante DE L’HUILE Essentielle DE Lavandula Angustifolia Miller Cultivée Dans Deux Régions Différentes DE L’algérie (Blida Et Chlef), Agrobiologia 12 (2022) 3244–3253.
18. S. Kammoun El Euch, D. Ben Hassine, S. Cazaux, N. Bouzouita, J. Bouajila. Salvia officinalis essential oil: Chemical analysis and evaluation of anti-enzymatic and antioxidant bioactivities. South Afr. J. Bot. 2018; 120. https://doi.org/10.1016/j.sajb.2018.07.010.
19. M. Bouaziz, T. Yangui, S. Sayadi, A. Dhouib, Disinfectant properties of essential oils from Salvia officinalis L. cultivated in Tunisia. Food Chem. Toxicol. Int. J. Publ. Br. Ind. Biol. Res. Assoc. 2009; 47: 2755–2760. https://doi.org/10.1016/j.fct.2009.08.005.
20. Z. Khiya, M. Hayani, A. Gamar, S. Kharchouf, S. Amine, F. Berrekhis, A. Bouzoubae, Z. Touria, F. Elhilali, Valorization of the Salvia officinalis L of the Morocco bioactive extracts: Phytochemistry, antioxidant and anticorrosive activities. J. King Saud Univ. - Sci. 2018; 31. https://doi.org/10.1016/j.jksus.2018.11.008