Author(s):
Tirth Thaker, Dipen Panchani, Sweta Maurya, Siddharajsinh Bariya, Hardik khant
Email(s):
tirth6582@gmail.com
DOI:
10.52711/0974-360X.2025.00210 
Address:
Tirth Thaker*, Dipen Panchani, Sweta Maurya, Siddharajsinh Bariya, Hardik khant
Department of Chemistry, Parul Institute of Applied Sciences, Parul University, Waghodia, Vadodara - 391760, Gujarat, India.
*Corresponding Author
Published In:
Volume - 18,
Issue - 4,
Year - 2025
ABSTRACT:
Bis-indole analogs are synthesized by condensing aldehyde and indole and characterized by spectral analysis. The compounds were evaluated for antimicrobial activity against Enterobacter, Escherichia coli, Staphylococcus aureus, and Bacillus strains and showed promising results. Furthermore, an in silico ADME assessment of these drugs was performed. Only a small number of compounds were found to pass the projected toxicity examination, whereas all were found to pass the ADME evaluation. This research serves as a starting point for the discovery of new compounds with intriguing properties and minimal toxicity.
Cite this article:
Tirth Thaker, Dipen Panchani, Sweta Maurya, Siddharajsinh Bariya, Hardik khant. Synthesis, Biological Evolution and ADME Studies of Bis-Indole Analogues. Research Journal of Pharmacy and Technology. 2025;18(4):1469-3. doi: 10.52711/0974-360X.2025.00210
Cite(Electronic):
Tirth Thaker, Dipen Panchani, Sweta Maurya, Siddharajsinh Bariya, Hardik khant. Synthesis, Biological Evolution and ADME Studies of Bis-Indole Analogues. Research Journal of Pharmacy and Technology. 2025;18(4):1469-3. doi: 10.52711/0974-360X.2025.00210 Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-4-1
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