Author(s): Nazira Sarkis, Saad Antakli, Amjad Qabawa

Email(s): nazirasarkis@gmail.com , profnazira@alepuniv.edu.sy , antakli@scsnet.org , amjadkabaweh1995@gmail.com

DOI: 10.52711/0974-360X.2025.00197   

Address: Nazira Sarkis1, Saad Antakli2, Amjad Qabawa1
1Department of Analytical and Food Chemistry, Faculty of Pharmacy, University of Aleppo, Aleppo, Syria.
2Department of Chemistry Faculty of Science University of Aleppo, Aleppo, Syria.
*Corresponding Author

Published In:   Volume - 18,      Issue - 3,     Year - 2025


ABSTRACT:
This article discusses the levels of heavy metals such as copper, lead, and cadmium in various foodstuffs consumed by children in the Syrian market. It analyzed two cereal products, Brentolak and Sami, using atomic absorption spectroscopy (AAS) and a novel wet digestion method developed for precision and accuracy. Samples from all flavors and production dates of Brentolak and Sami cereals were collected and analyzed. The research showed varying levels of heavy metals in different samples and flavors. The concentrations of Cu, Pb, and Cd ranged from 1.366-1.51 µg/g, 0.014-0.038 µg/g, and 0.014-0.042 µg/g, respectively. For lead (Pb), the HRI values were generally below 1, indicating levels within safe limits. However, some flavors, such as Wheat and Milk and Rice and Milk from Brentolak, had values approaching 1, suggesting that while the risk is not immediate, continuous monitoring is required to ensure lead levels do not exceed safe thresholds and for Cadmium (Cd) levels, on the other hand, were relatively higher compared to the reference dose, with some samples, such as Sami Fruits and Brentolak Rice and Milk, displaying HRI values approaching or exceeding 1. This suggests a potential health risk for infants consuming these products over time, necessitating measures to reduce cadmium exposure in these formulas For Lead (Pb) CR values were consistently below 10?6, indicating negligible risk across all formulas for both brands and for Cadmium (Cd) CR were below 10?6 too across all formulas, The Sami Fruits and Brentolak Rice and Milk flavors presented the highest CR values. Comparative analysis with international standards shows safe levels of copper, but lead and cadmium levels require cautious monitoring and management. This highlights the need for serious quality control measures coupled with regulatory oversight, especially for food products meant for children, to ensure safety. These findings indicate the necessity for routine surveillance and strict control to limit the risk of heavy metals in children's foods.


Cite this article:
Nazira Sarkis, Saad Antakli, Amjad Qabawa. Determination of some Heavy Metals in Children's Food. Research Journal of Pharmacy and Technology. 2025;18(3):1368-3. doi: 10.52711/0974-360X.2025.00197

Cite(Electronic):
Nazira Sarkis, Saad Antakli, Amjad Qabawa. Determination of some Heavy Metals in Children's Food. Research Journal of Pharmacy and Technology. 2025;18(3):1368-3. doi: 10.52711/0974-360X.2025.00197   Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-3-58


REFERENCES:
1.    Klerks, M., Bernal, M. J., Roman, S., Bodenstab, S., Gil, A., and Sanchez-Siles, L. M. Infant cereals: Current status, challenges, and future opportunities for whole grains. Nutrients. 2019; 11(2): 473.
2.    Samar, A., Oussama, C., Oumaima, N., Kamal, K., and Aziz, E. Accumulation of heavy metals in fish and their impacts on human health: A systematic literature review. Research Journal of Pharmacy and Technology. 2023; 16(1): 209-214.
3.    Sapna, S., Sanju, N., and Anju, D. Elemental analysis in Piper betle Linn. and Jatropha gossypifolia Linn. leaves: Biosafety studies. Research Journal of Pharmacy and Technology. 2018; 11(11): 5078-5082.
4.    Amarh, F. A., Agorku, E. S., Voegborlo, R. B., Ashong, G. W., and Atongo, G. A. Health risk assessment of some selected heavy metals in infant food sold in Wa, Ghana. Heliyon. 2023; 9(5): e16225.
5.    Antakli, S., and Nahas, F. Content estimation of the mineral elements (Zn, Mg, Cu, Fe, Co, and Ni) in parsley at Aleppo region, Syria, by flame atomic absorption spectroscopy. Research Journal of Pharmacy and Technology. 2023; 16(6): 2683-2688.
6.    Akhlaq, M., Iqbal, A. A., Ahmad, S. Z., and Meena, R. P. Heavy metals determination in microwave digested aqueous extracts of fresh and market samples of some plant origin drugs with reference to their preliminary comparative physico-chemical evaluation. Research Journal of Pharmacognosy and Phytochemistry. 2021; 13(1): 11-17.
7.    Milan, H., Ashutosh, P., and Singh, C. R. Heavy metal levels in selected leafy vegetables obtained from local market of Dharmjaigarh, Chhattisgarh, India. Asian Journal of Research in Chemistry. 2017; 10(3): 354-358.
8.    Bais, S. K., Chandewar, A. V., Wargantiwar, D. W., and Charjan, S. M. Evaluation of heavy metals in some marketed ayurvedic formulations using AAS. Asian Journal of Pharmaceutical Analysis. 2014; 4(1): 11-16.
9.    Akinyele, I. O., and Shokunbi, O. S. Comparative analysis of dry ashing and wet digestion methods for the determination of trace and heavy metals in food samples. Food Chemistry. 2015; 173: 682-684.
10.    Antakli, S., Sarkis, N., and Nahas, F. Sample microwave digestion for the determination of manganese, iron, zinc, copper, and nickel in catfish consumed in Syria by flame atomic absorption spectrometry. Research Journal of Pharmacy and Technology. 2018; 11(5): 2094-2099.
11.    Ajantha, A. T., and Indirani, B. Comparison of heavy metal concentration in various laterite profiles in Kanyakumari district. Asian Journal of Research in Chemistry. 2018; 11(2): 244-246.
12.    Chandra, M. J. B., Chandaka, M., Ramanji, R. K., and Mohammed, O.Estimation of metals in herbal leaves by ash extracts by using ICP-OES and flame photometer. Asian Journal of Pharmaceutical Analysis. 2019; 9(2): 82-88
13.    Rajeshwari, B. M., and Patil, S. J. Heavy metals status in soils of Ballari District using Atomic Absorption Spectroscopy (AAS). Asian Journal of Research in Chemistry. 2018; 11(4): 701-704.
14.    Venugopal, N. V. S., Sumalatha, B., Syedabano, and Srinivas, G.  Trace element levels in fruits and vegetables by using atomic absorption spectrophotometer (AAS). Asian Journal of Research in Chemistry. 2011; 4(11): 1769-1771.
15.    Öztürk, K., Çalışkan, Ç. E., Akıncı, Z., and Çiftçi, H. Assessment of some element content and potential health risks in infant formulas available in Turkish markets. Turkish Journal of Analytical Chemistry. 2023; 5(1): 17-24.
16.    Heboto, G. F., Gizachew, M., Birhanu, T., and Srinivasan, B. (2024). Health risk assessment of trace metal concentrations in cereal-based infant foods from Arba Minch Town, Ethiopia. Journal of Food Composition and Analysis, 135, 106621.
17.    Su, C., Zheng, N., Gao, Y., Huang, S., Yang, X., Wang, Z., Yang, H., and Wang, J. Content and dietary exposure assessment of toxic elements in infant formulas from the Chinese market. Foods, 2020; 9(12): 1839.
18.    Pandelova, M., Lopez, W. L., Michalke, B., and Schramm, K. W.  Ca, Cd, Cu, Fe, Hg, Mn, Ni, Pb, Se, and Zn contents in baby foods from the EU market: Comparison of assessed infant intakes with the present safety limits for minerals and trace elements. Journal of Food Composition and Analysis. 2012; 27(2): 120-127.

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank

Journal Policies & Information


Recent Articles




Tags


Not Available