Author(s):
Sumi Barman, Md Tamijur Rahman
Email(s):
phtamijurr@gmail.com
DOI:
10.52711/0974-360X.2025.00157 
Address:
Sumi Barman1, Md Tamijur Rahman2,3*
1Royal School of Pharmacy, The Assam Royal Global University, Guwahati, Assam 781035, India.
2Department of Pharmaceutical Sciences, Assam University, Silchar, 788011, India.
3Faculty of Pharmacy, Bir Tikendrajit University, Imphal, Manipur 795003, India.
*Corresponding Author
Published In:
Volume - 18,
Issue - 3,
Year - 2025
ABSTRACT:
Mikania micrantha is an evergreen herb belonging to the family Asteraceae. In the current study, the investigation was conducted to assess the HPLC profiling of the methanolic extracts of the leaves of Mikania micrantha. In-vitro anti-oxidant and antidiabetic activity of the methanolic extract was also evaluated using different standard methods. For Antioxidant studies, the total Phenolic content assay, total Flavonoid content assay, DPPH Radical scavenging assay, and Hydrogen peroxide radical scavenging assaywere carried out. In-vitro anti-diabetic activity was evaluated using a-amylase inhibition assay. The IC50 value was determined for each assay. When compared to other common antioxidants, the methanolic extract of Mikania micrantha leaves has shown potent anti-oxidant activity by suppressing DPPH radicals. It was seen that there was a dose-dependent increase in percentage inhibitory activity against alpha-amylase enzyme while performing the in vitro anti-diabetic evaluation using a-amylase as standard.
Cite this article:
Sumi Barman, Md Tamijur Rahman. Evaluation of In-vitro Anti-oxidant and Anti-diabetic Potential of Mikania micrantha Methanolic Leaves Extract. Research Journal Pharmacy and Technology. 2025;18(3):1096-0. doi: 10.52711/0974-360X.2025.00157
Cite(Electronic):
Sumi Barman, Md Tamijur Rahman. Evaluation of In-vitro Anti-oxidant and Anti-diabetic Potential of Mikania micrantha Methanolic Leaves Extract. Research Journal Pharmacy and Technology. 2025;18(3):1096-0. doi: 10.52711/0974-360X.2025.00157 Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-3-18
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