Author(s):
H. Damour, M. Oussekkour, Z. Mennane, S. El Hajjaji
Email(s):
h.damour@cnrst.ma
DOI:
10.52711/0974-360X.2025.00085 
Address:
H. Damour1,2*, M. Oussekkour3, Z. Mennane4, S. El Hajjaji2
1Chemistry Department, National Center for Scientific and Technical Research, Mohammed V University, Rabat, Morocco.
2Laboratory of Molecular Spectroscopy Modelling, Materials, Nanomaterials,
Water and Environment, CERNE2D, Faculty of Sciences, Mohammed V University in Rabat, Morocco.
3National Office of Electricity and drinking water-water Branch, Rabat, Morocco.
4Department of Biology Faculty of Sciences Tetouan, Morocco.
*Corresponding Author
Published In:
Volume - 18,
Issue - 2,
Year - 2025
ABSTRACT:
Context: Boswellia carterii is a yellowish substance extracted from the cuttings of Boswellia sp. Plant, it is found in several parts of the world. Boswellia Carterrii has been traditionally used for the treatment of several inflammatory diseases, and bacterial resistance to antibiotics has recently increased the use of bioproducts. Objectives: the chemical investigation and assesses the antibacterial effect of the ASE extracts of the Boswellia carterii on 7 pathogenic bacterial strains (Escherichia coli, Salmonella spp, Staphylococcus saprophytoculis Staphylococcus epedrmidis, Staphylococcus aureus, Pseudomonas aeruginosa and Acinetobacter baumannii). Methods: Accelerated solvent extraction (ASE) was used for the first time to extract nonvolatile and volatile compounds from Boswellia carterii samples using three extractions solvents: n-Hexane, Dichloromethane (DCM), Methanol (MeOH), while gas chromatography–mass spectrometry (GC–MS) and headspace were used to study the components in the extracts. Results: Different compounds including mono-, sesqui- and di-terpenic compositions, were identified by GC-MS in the ASE extracts of Boswellia carterii that could have antibacterial effects on the studied strains. Conclusions: The different ASE extracts of the Boswellia carterii showed antibacterial effects and a positive impact on the phagocytic ratio of different studied strains.
Cite this article:
H. Damour, M. Oussekkour, Z. Mennane, S. El Hajjaji. Phytochemical Investigation by GC-MS and Antimicrobial Activities of Boswellia carterii Extract by Accelerated Solvent Extraction. Research Journal of Pharmacy and Technology.2025;18(2):571-8. doi: 10.52711/0974-360X.2025.00085
Cite(Electronic):
H. Damour, M. Oussekkour, Z. Mennane, S. El Hajjaji. Phytochemical Investigation by GC-MS and Antimicrobial Activities of Boswellia carterii Extract by Accelerated Solvent Extraction. Research Journal of Pharmacy and Technology.2025;18(2):571-8. doi: 10.52711/0974-360X.2025.00085 Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-2-17
REFERENCES:
1. A. Sharma, R. Nagraik, S. Sharma, P. Chauhan. In-vitro Antioxidant and Antimicrobial activities of Murraya koiengii and Ficus palmata leaf extracts from North-western Himalayan Region, Research Journal of Pharmacy and Technology. 2021: 4332–4336. https://doi.org/10.52711/0974-360X.2021.00752.
2. T. Rastogi, D.S. Ghorpade, U.A. Deokate, S.S. Khadabadi. Studies on Antimicrobial Activity of Boswellia serrata, Moringa oleifera and Vitex negundo: A comparison, Research Journal of Pharmacognosy and Phytochemistry. 2009; 1: 75–77.
3. M. Hemalatha, B. Arirudran, A. Thenmozhi, U.S.M. Rao. Antimicrobial Effect of Separate Extract of Acetone, Ethyl Acetate, Methanol and Aqueous from Leaf of Milkweed (Calotropis gigantea L.), Asian Journal of Pharmaceutical Research. 2011; 1: 102–107.
4. S.A. Anatolyevna, K.V. Alexandrovich, S.A. Nikolayevich, R.M. Victorovna, S.K. Nikolaevna. Method of obtaining of extract by the method of Modified Maceration, Research Journal of Pharmacy and Technology. 2019; 12: 5656–5658. https://doi.org/10.5958/0974-360X.2019.01033.3.
5. D. Bhosle, A. Janghel, S. Deo, P. Raut, C. Verma, S.S. Kumar, M. Agrawal, N. Amit, M. Sharma, T. Giri, D.K. Tripathi, A. Ajaz, A. Alexander. Emerging ultrasound assisted extraction (UAE) techniques as innovative green technologies for the effective extraction of the active phytopharmaceuticals. Research Journal of Pharmacy and Technology. 2015; 8: 963–970. https://doi.org/10.5958/0974-360X.2015.00161.4.
6. N. Choudhary, A. Suttee, Effect of conventional method and microwave-assisted extraction on phytoconstituents of Operculina turpethum, Research Journal of Pharmacy and Technology. 2020; 13: 6109–6112. https://doi.org/10.5958/0974-360X.2020.01065.3.
7. A. Janghel, S. Deo, P. Raut, D. Bhosle, C. Verma, S. Kumar, M. Agrawal, N. Amit, M. Sharma, T. Giri, D. Tripathi, A. Ajaz, A. Alexander. Supercritical Fluid Extraction (SFE) Techniques as an Innovative Green Technologies for the Effective Extraction of the Active Phytopharmaceuticals. Research Journal of Pharmacy and Technology. 2015; 8; 775. https://doi.org/10.5958/0974-360X.2015.00125.0.
8. S. Bhusari, S. Morey, K. Nikam, P. Wakte. Comparative Evaluation of Baicalein from Oroxylum indicum by using Conventional and Non-Conventional Extraction Methodology. Research Journal of Pharmacy and Technology. 2019; 12: 1817. https://doi.org/10.5958/0974-360X.2019.00303.2.
9. B.E. Jose, P. Panneer Selvam. Identification of Phytochemical Constituents in the Leaf Extracts of Azima tetracantha Lam using Gas Chromatography-Mass Spectrometry (GC-MS) analysis and Antioxidant Activity. Asian Journal of Research in Chemistry. 2018; 11: 857–852. https://doi.org/10.5958/0974-4150.2018.00150.5.
10. A. Fahim, M. Shakir Ghouse, S. Islam, M. Danish, S. Mehmood, S. Saniya, Q. Fatima. Isolation and Identification of Boswellic Acids by Modern Analytical Techniques. Asian Journal of Pharmaceutical Analysis. 2021: 98–112. https://doi.org/10.52711/2231-5675.2021.00018.
11. A.Sh.M. Alhesnawi, B. Almjalawi. Antibacterial Activity of Boswellia carterii Aqueous Extract and Its Effect on Phagocytosis in vitro. Archives of Razi Institute. 77 (2022). https://doi.org/10.22092/ARI.2022.356956.1946.
12. M.K. Senghani, P.M. Patel. Pharmacognostic and Phytochemical Study of Oleo Gum Resin from Boswellia serrate. Research Journal of Pharmacognosy and Phytochemistry. 2013; 5: 244–250.
13. C. Mathe, G. Culioli, P. Archier, C. Vieillescazes. Characterization of archeological frankincense by gas chromatography mass spectrometry. Journal of Chromatography. A 1023 (2004) 277–85. https://doi.org/10.1016/j.chroma.2003.10.016.