Author(s):
V. Bhawani, A. Perumal
Email(s):
bhawanikmc@gmail.com , perumalanat1sas@gmail.com
DOI:
10.52711/0974-360X.2025.00705 
Address:
V. Bhawani1, A. Perumal2
1Full time Research Scholar, Srinivasan Medial College and Hospital, Dhanalakshmi Srinivasan University, Samayapuram, Tiruchirappalli - 621 112.
2Professor, Department of Anatomy, Srinivasan Medial College and Hospital, Dhanalakshmi Srinivasan University, Samayapuram, Tiruchirappalli - 621 112.
*Corresponding Author
Published In:
Volume - 18,
Issue - 10,
Year - 2025
ABSTRACT:
Background: The plant extracts are used as medicine either based upon nature of compounds present or their solubility in various chemicals. The leaves of Amaranthus caudatus are used from ancient days by tribal people to cure lung diseases, liver diseases, renal diseases, stomach ulcers and haemorrhoids. Previous studies were conducted with solvents like methanol and ethanol. Both these solvents revealed many phytocompounds which has therapeutic values. The analysis repoted still left incomplete, hence complete knowledge of all compounds extracted with other common solvents are essential to get whole idea. Aim: To gain the knowledge about the different chemicals present in the aqueous, ethyl acetate and hexane leaf extract of Amaranthus caudatus. Material And Methods: The combination of Gas Chromatography GC-2010 and QP-2020 SHIMADZU Japan corporation analyzers with different solvent mixture were used to encounter the list of bioactive phytochemicals. NIST 20 M library were used to match the available phytochemicals with their corresponding details. Results: The hot aqueous extraction was revealed the presence of 61 phytochemicals with Cis 11 ecosinamide, 1Heptanol, 1,2-Diphenyl ethane, Hexadecenoic acid, Cis Sinapyl alcohol, Undecane were some of the major components seen. The Ethyl acetate extraction was confirmed 60 phytocomponents with Dl alpha tocopherol, Trihydrocholanic acid, Eicosane, Tetradecane were the major compounds seen during the extraction while Hexane extraction method was revealed the presence of 47 compounds with Squalene, Octacosane 2 Methyl, Heneicosane, 2 Methyl tetracosane as the major components. Conclusion: Aqueous extraction was revealed cis 11 Eicosenamide and Ethyl acetate extract was revealed dl alpha tocopherol while the Hexane extraction detected Squalene in the highest peaks. Cis 11 Ecosenamide is well known anticancer agent, Dl Alpha tocopherol is form of vitamin E used for sterility related problems and squalene protect the skin damages as well as loaded with anti-inflammatory properties. Most of the components in aqueous extract had anti-inflammatory properties. Ethyl acetate extract had antimicrobial properties while the hexane extract had mixed responses with antioxidant, antimicrobial and anti-inflammatory functions.
Cite this article:
V. Bhawani, A. Perumal. GC-MS Analysis of Bioactive Materials in Amaranthus caudatus Based on Chemical Polarity. Research Journal of Pharmacy and Technology. 2025;18(10):4891-6. doi: 10.52711/0974-360X.2025.00705
Cite(Electronic):
V. Bhawani, A. Perumal. GC-MS Analysis of Bioactive Materials in Amaranthus caudatus Based on Chemical Polarity. Research Journal of Pharmacy and Technology. 2025;18(10):4891-6. doi: 10.52711/0974-360X.2025.00705 Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-10-44
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