Author(s): Aigul Medeshova, Perizat Orazbayeva, Akniet Dosai, Aizhan Essedova, Karlygash Kaiyrbekova, Zauresh Mukhametzhanova, Aida Shahabayeva, Bekzhan Orazbayev

Email(s): perizat_abay@mail.ru

DOI: 10.52711/0974-360X.2025.00693   

Address: Aigul Medeshova, Perizat Orazbayeva*, Akniet Dosai, Aizhan Essedova, Karlygash Kaiyrbekova, Zauresh Mukhametzhanova, Aida Shahabayeva, Bekzhan Orazbayev
NCJSC "Karaganda Medical University", 100000, Kazakhstan, Karaganda City, St. Gogol 40.
*Corresponding Author

Published In:   Volume - 18,      Issue - 10,     Year - 2025


ABSTRACT:
To determine the rational technology for the production of medicines, an important element of the study of medicinal plant raw materials is the establishment of technological parameters. This article presents the results of studying technological parameters (grinding, specific gravity, bulk weight, bulk weight, porosity, porosity, free volume of the raw material layer, extractant absorption coefficients) and individual numerical indicators (loss in mass during drying, mass fraction of total ash, content of ash insoluble in hydrochloric acid, mineral impurities, organic impurities) of vegetable raw materials high-grade elecampane (Inula helenium L.). The dried aboveground part of the elecampane (Inula helenium L.) was used as an object. The following parameters (Inula helenium L.) were studied and determined: pulverization – 1-3 mm; specific gravity – 0.86 g/cm3; bulk weight – 0.3 g/cm3; bulk weight – 0.75 g/cm3; porosity – 0.13g/cm3; porosity - 0.6 g/cm3; free volume of the layer – 0.65 g/cm3; extractant absorption coefficient: water – 5.13 ml/g; 30% ethanol – 4.11 ml/g; 50% ethanol – 3.89 ml/g; 70% ethanol – 3.55 ml/g; 90% ethanol – 2.71 ml/g. The obtained data will be used in the technological process for the production of extracts from the roots and rhizomes of Inula helenium L.


Cite this article:
Aigul Medeshova, Perizat Orazbayeva, Akniet Dosai, Aizhan Essedova, Karlygash Kaiyrbekova, Zauresh Mukhametzhanova, Aida Shahabayeva, Bekzhan Orazbayev. Research Journal of Pharmacy and Technology. 2025;18(10):4810-4. doi: 10.52711/0974-360X.2025.00693

Cite(Electronic):
Aigul Medeshova, Perizat Orazbayeva, Akniet Dosai, Aizhan Essedova, Karlygash Kaiyrbekova, Zauresh Mukhametzhanova, Aida Shahabayeva, Bekzhan Orazbayev. Research Journal of Pharmacy and Technology. 2025;18(10):4810-4. doi: 10.52711/0974-360X.2025.00693   Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-10-32


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