ABSTRACT:
The medicinal properties of a plant depend on the phytochemical compounds present in plant parts. These phytochemicals are secondary metabolites produced within plants to fight against pathogens and environmental stress. These bioactive phytoconstituents possess therapeutic properties which make them significant for the production of novel drugs. Genus Tephrosia is known for its medicinal properties and used in ayurvedic and traditional medicines for a long time, but there is no report exists on phytochemical compounds found in Tephrosia wallichii. The present study aimed to determine bioactive compounds found in the leaves of T. wallichii. Preliminary phytochemical tests were done to confirm the presence or absence of chemical compounds belonging to various chemical groups. Further, Gas chromatography-mass - Mass spectroscopy analysis was carried out to identify the bioactive compounds of the methanolic leaf extract of T. wallichii. Phytochemical screening of methanolic leaf extract confirmed the presence of amino acids, carbohydrates, protein, alkaloids, phenols, flavonoids, terpenoids, saponins, phytosterols and glycosides in leaf extract. GC-MS analysis revealed the presence of fifty-three phytoconstituents in methanolic leaf extract, out of them fifty-two were identified. The presence of many bioactive compounds proved the therapeutic importance of this Tephrosia species; hence it can be considered for the development of novel drugs to cure several diseases.
Cite this article:
Vandana. Phytochemical Screening and GC-MS Profiling of Methanolic Leaf Extract of Tephrosia wallichii Graham of Indian thar Desert. Research Journal of Pharmacy and Technology. 2025;18(1):159-4. doi: 10.52711/0974-360X.2025.00024
Cite(Electronic):
Vandana. Phytochemical Screening and GC-MS Profiling of Methanolic Leaf Extract of Tephrosia wallichii Graham of Indian thar Desert. Research Journal of Pharmacy and Technology. 2025;18(1):159-4. doi: 10.52711/0974-360X.2025.00024 Available on: https://rjptonline.org/AbstractView.aspx?PID=2025-18-1-24
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