ABSTRACT:
One of the largest manufacturing industries in the world is paint. Certain compounds included in paints have been identified as carcinogenic. The aim of this study was to detect the DNA damage in the lymphocytes of Jordanian paint workers by using Comet and micronucleus assays. In this research, the genotoxic impact of paint molecules was evaluated in the peripheral blood lymphocytes of 50 paint workers with healthy controls using micronucleus and Comet assays. The paint worker group's chromosomal abnormalities showed a high frequency of MNi to those in the unexposed group. According to OTM and % tail DNA parameters, the exposed group had significantly more DNA damage than the unexposed group (p<0.001). In conclusion, the high frequency of DNA damage found in this research emphasizes the critical need for action to lower the heightened risk of cancer, as well as to impose strict health regulations and use suitable protective gear at work.
Cite this article:
Maysa Alhawamdeh. Evaluation of the Genotoxicity in Jordanian Paint Workers' Lymphocytes. Research Journal of Pharmacy and Technology. 2024; 17(9):4417-1. doi: 10.52711/0974-360X.2024.00682
Cite(Electronic):
Maysa Alhawamdeh. Evaluation of the Genotoxicity in Jordanian Paint Workers' Lymphocytes. Research Journal of Pharmacy and Technology. 2024; 17(9):4417-1. doi: 10.52711/0974-360X.2024.00682 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-9-43
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