Author(s):
Anis Irmawati, Rahmad Yuliantoro, Sidarningsih, Retno Indrawati Roestamadji, Tantiana, Ira Arundina, Yassir Ahmad Azzaim, Noor Faizah Balqis, Fitriatuz Zakia, Ovin Gabriella Notonugroho, Vitra Nuraini Helmi, Ahmed Alareqi
Email(s):
anis-m@fkg.unair.ac.id
DOI:
10.52711/0974-360X.2024.00673 
Address:
Anis Irmawati1*, Rahmad Yuliantoro2, Sidarningsih1, Retno Indrawati Roestamadji1, Tantiana1, Ira Arundina1, Yassir Ahmad Azzaim3, Noor Faizah Balqis4, Fitriatuz Zakia3, Ovin Gabriella Notonugroho2, Vitra Nuraini Helmi3, Ahmed Alareqi5
1Department of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
2Profession Student, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
3Master Study Program, Dental Health Science, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
4Postgraduate Student, Faculty of Public Health, Universitas Airlangga, Surabaya, Indonesia.
5Jordan University of Science and Technology, Irbid, Jordan.
*Corresponding Author
Published In:
Volume - 17,
Issue - 9,
Year - 2024
ABSTRACT:
Background: Streptococcus mutans is a bacterium that causes caries. Various attempts have been made to treat caries such as restoration and the use of toothpaste/mouthwash made from antibacterial substances such as triclosan and chlorhexidine, but these efforts have weakness such as the occurrence of secondary caries and tooth discoloration. Based on this, we need an alternative material that can solve the problem without causing side effects, as is the case with natural ingredients from papaya leaves and seeds. Papaya leaves and seeds have antibacterial substances such as flavonoids, alkaloids, saponins, phenols and tannins. Purpose: This study aims to prove the distinguish of antibacterial activity of papaya seed and leaves extract (Carica papaya L) against Streptococcus mutans. Methods: Experimental study with a post test only control group design. Tests carried out with phytochemical tests, dilution, and diffusion. Results: Phytochemical test showed that papaya leaves contained flavonoids (6.10%), alkaloids (3.97%), saponins (4,95%), phenols (6,52%), and tannins (3,28%); while in papaya seeds flavonoids (3,05%), alkaloids (4,18%), saponins (2,98%), phenols (3,10%), and tannins (2,90%). The dilution test showed that papaya leaves had MIC (10% concentration) and MBC (20% concentration), while papaya seeds had MIC (20% concentration) and MBC (40% concentration). The diffusion test showed that the diameter of the inhibition zone of papaya leaves was larger than that of papaya seeds. Conclusion: There are differences in the antibacterial activity of papaya seeds and papaya leaves (Carica papaya L) against Streptococcus mutans. Papaya leaves have greater antibacterial activity than papaya seeds.
Cite this article:
Anis Irmawati, Rahmad Yuliantoro, Sidarningsih, Retno Indrawati Roestamadji, Tantiana, Ira Arundina, Yassir Ahmad Azzaim, Noor Faizah Balqis, Fitriatuz Zakia, Ovin Gabriella Notonugroho, Vitra Nuraini Helmi, Ahmed Alareqi. The difference of Antibacterial properties extract seeds Papaya and Papaya leaves (Carica papaya L) against Streptococcus mutans. Research Journal of Pharmacy and Technology. 2024; 17(9):4353-2. doi: 10.52711/0974-360X.2024.00673
Cite(Electronic):
Anis Irmawati, Rahmad Yuliantoro, Sidarningsih, Retno Indrawati Roestamadji, Tantiana, Ira Arundina, Yassir Ahmad Azzaim, Noor Faizah Balqis, Fitriatuz Zakia, Ovin Gabriella Notonugroho, Vitra Nuraini Helmi, Ahmed Alareqi. The difference of Antibacterial properties extract seeds Papaya and Papaya leaves (Carica papaya L) against Streptococcus mutans. Research Journal of Pharmacy and Technology. 2024; 17(9):4353-2. doi: 10.52711/0974-360X.2024.00673 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-9-34
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