Author(s):
Chevidaev V.V., Rodin M.N., Malysheva M.O., Shalburova S. G. S., Guo B.2, Ji R., Bokov D.O., Terekhov R.P., Ma J., He X.
Email(s):
chevidaev_v_v@staff.sechenov.ru , hexintn@gdpu.edu.cn
DOI:
10.52711/0974-360X.2024.00664 
Address:
Chevidaev V.V.1*, Rodin M.N.1, Malysheva M.O.1, Shalburova S. G. S.1, Guo B.2, Ji R.2, Bokov D.O.1, Terekhov R.P.1, Ma J.2, He X.2*
1Sechenov First Moscow State Medical University, 8 Trubetskaya St., bldg. 2, Moscow, 119991, Russia.
2Guangdong Pharmaceutical University, No. 280, Waihuan East Road, University Town, Guangzhou City, Guangdong Province, China.
*Corresponding Author
Published In:
Volume - 17,
Issue - 9,
Year - 2024
ABSTRACT:
Ginseng roots are medicinal plant raw materials used in pharmaceutical practice in a number of countries due to their pharmacological activities, including tonic. Ginsenosides of ginseng are the main group of biologically active substances responsible for the pharmacological effects of ginseng.One of the modern methods for analyzing ginsenosides is UPLC-MS/MS, which allows one to gain a broad understanding of the ginsenoside profile. The authors used TLC analysis and UPLC-MS/MS to identify and quantify ginsenosides. Of the 18 identified ginsenosides, ginsenosidesRb 1, Rc, Re, Rg1 can be considered as marker ones. These approaches can serve as the basis for the development of regulatory documentation for ginseng and medicines based on it. The total content of ginsenoside in tinctures is higher than in the medicinal plant material of white ginseng roots. Chemical compounds studied in this article: Ginsenoside Rb1 (PubChem CID: 9898279); Ginsenoside Rb2 (PubChem CID: 6917976); Ginsenoside Rb3 (PubChem CID: 12912363); GinsenosideRc (PubChem CID: 12855889); Ginsenoside Rd (PubChem CID: 24721561); Ginsenoside Re (PubChem CID: 119307); Ginsenoside Rf (PubChem CID: 441922); Ginsenoside Rg1 (PubChem CID: 441923); Ginsenoside S-Rg2 (PubChem CID: 12912322); Ginsenoside Ro (PubChem CID: 11815492); Ginsenoside S-Rg3 (PubChem CID: 9918693); Ginsenoside Rg5 (PubChem CID: 11550001); Ginsenoside R-Rh1 (PubChem CID: 21599923); Ginsenoside S-Rh2 (PubChem CID: 91668381); Ginsenoside Rk1 (PubChem CID: 11499198); Ginsenoside Rk3 (PubChem CID: 75412555); Ginsenoside F2 (PubChem CID: 9918692); Ginsenoside F3 (PubChem CID: 46887678); Ginsenoside F4 (PubChem CID: 73717457); Ginsenoside CK (PubChem CID: 9852086).
Cite this article:
Chevidaev V.V., Rodin M.N., Malysheva M.O., Shalburova S. G. S., Guo B.2, Ji R., Bokov D.O., Terekhov R.P., Ma J., He X.. Ginsenoside Profile of White Ginseng Roots and Tinctures. Research Journal of Pharmacy and Technology. 2024; 17(9):4299-3. doi: 10.52711/0974-360X.2024.00664
Cite(Electronic):
Chevidaev V.V., Rodin M.N., Malysheva M.O., Shalburova S. G. S., Guo B.2, Ji R., Bokov D.O., Terekhov R.P., Ma J., He X.. Ginsenoside Profile of White Ginseng Roots and Tinctures. Research Journal of Pharmacy and Technology. 2024; 17(9):4299-3. doi: 10.52711/0974-360X.2024.00664 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-9-25
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