Author(s): Hemant A. Sawarkar, Sachin C. Kale, Ram D. Bawankar, Kailas R. Biyani

Email(s): mrhemant1979@gmail.com

DOI: 10.52711/0974-360X.2024.00405   

Address: Hemant A. Sawarkar1*, Sachin C. Kale1, Ram D. Bawankar2, Kailas R. Biyani1
1Anuradha College of Pharmacy, Sakegaon Road, Chikhali, Buldhana, Maharashtra.
2Agnihotri College of Pharmacy, Wardha, Maharashtra.
*Corresponding Author

Published In:   Volume - 17,      Issue - 6,     Year - 2024


ABSTRACT:
This research aimed to investigate the biofilm inhibiting activity of essential oil derived from Bunium persicum and determine its potential as a natural alternative for combating biofilm-related infections. The essential oil from Bunium persicum was extracted using the steam distillation method. The antimicrobial activity of the oil was evaluated using the cup plate method against selected pathogenic microorganisms. The minimum inhibitory concentration (MIC) values were determined to assess the concentration at which the oil effectively inhibited microbial growth. The biofilm inhibitory potential of the oil was evaluated using the micro titer plate assay. The oil exhibited significant antimicrobial activity against Streptococcus mutans, Staphylococcus aureus, Lactobacillus sporogens, Bacillus coagulans, and Candida albicans, as evidenced by the substantial zones of inhibition observed in agar well diffusion assay. The MIC values indicated effective inhibition of microbial growth at a range of concentrations. Moreover, the oil demonstrated remarkable suppression of biofilm formation for all tested organisms in the micro titer plate assay. To the best of our knowledge, this is one of the pioneering studies investigating the biofilm inhibitory activity of essential oil from Bunium persicum. While previous research has focused on the antimicrobial properties of this oil, its potential as a biofilm inhibitor has not been extensively explored.


Cite this article:
Hemant A. Sawarkar, Sachin C. Kale, Ram D. Bawankar, Kailas R. Biyani. Exploring the Biofilm Inhibiting potential of Bunium persicum Essential Oil: A Promising Strategy for Combating Microbial Biofilm. Research Journal of Pharmacy and Technology. 2024; 17(6):2592-6. doi: 10.52711/0974-360X.2024.00405

Cite(Electronic):
Hemant A. Sawarkar, Sachin C. Kale, Ram D. Bawankar, Kailas R. Biyani. Exploring the Biofilm Inhibiting potential of Bunium persicum Essential Oil: A Promising Strategy for Combating Microbial Biofilm. Research Journal of Pharmacy and Technology. 2024; 17(6):2592-6. doi: 10.52711/0974-360X.2024.00405   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-6-24


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