Author(s): Ahmad Malek Ismael, Suzan Samra, Chadi soukkarieh

Email(s): ahmadismaealkk@gmail.com , suzansamra794@hotmail.com , soukkarieh@gmail.com

DOI: 10.52711/0974-360X.2024.00360   

Address: Ahmad Malek Ismael1, Suzan Samra2, Chadi soukkarieh3
1Tishreen University, Faculty of Pharmacy, Department of Biochemistry and Microbiology.
2Tishreen University, Faculty of Pharmacy, Department of Biochemistry and Microbiology.
3Damascus University Faculty of Science, Department of Animal Biology.
*Corresponding Author

Published In:   Volume - 17,      Issue - 5,     Year - 2024


ABSTRACT:
Leishmaniasis is a worldwide disease that manifests in different clinical forms caused by obligate intracellular protozoan parasites of the genus Leishmania. The parasite transmission occurs by the bite of sandflies and affects many countries across the world. Its transmission cycle is associated with the presence of bad conditions and crisis. Syria is considered an endemic area and has a long history of cutaneous and visceral leishmaniasis. The crisis that gripped the country changed the leishmaniasis situation drastically and resulted in a redistribution of cases around the country, especially after the massive displacement toward safe cities such as Lattakia, which is known for registering few CL cases every year. In this study, we aimed to shed light on the real number of cases that originated in Latakia Province. Moreover, we determined the species responsible for CL lesions using polymerase chain reaction-restriction fragment DNA length polymorphism (PCR-RFLP). Our results show that just about less than one-third of cutaneous leishmaniasis cases diagnosed in Lattakia were originally acquired from the province, while the rest of the cases were acquired from other endemic areas. In addition, we found that 98.2% of all the diagnosed cases were caused by L.tropica, while 1.8% were caused by L.major.


Cite this article:
Ahmad Malek Ismael, Suzan Samra, Chadi soukkarieh. Ahmad Malek Ismael, Suzan Samra, Chadi soukkarieh. Research Journal of Pharmacy and Technology. 2024; 17(5):2296-0. doi: 10.52711/0974-360X.2024.00360

Cite(Electronic):
Ahmad Malek Ismael, Suzan Samra, Chadi soukkarieh. Ahmad Malek Ismael, Suzan Samra, Chadi soukkarieh. Research Journal of Pharmacy and Technology. 2024; 17(5):2296-0. doi: 10.52711/0974-360X.2024.00360   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-5-56


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