Author(s): Ibrahim Alfarrayeh

Email(s): alfarrayeh@ttu.edu.jo

DOI: 10.52711/0974-360X.2024.00354   

Address: Ibrahim Alfarrayeh
Department of Applied Biology, Faculty of Science, Tafila Technical University, Tafila 66110, Jordan.
*Corresponding Author

Published In:   Volume - 17,      Issue - 5,     Year - 2024


ABSTRACT:
The aim of this study was to explore the antibacterial and antioxidant properties of methanolic extracts obtained from seven distinct medicinal plants, namely Phlomis brachyodon, Salvia dominica, Hypericum triquetrifolium, Origanum majorana, Foeniculum vulgare, Glycyrrhiza glabra, and Curcuma longa. To assess antibacterial activity, the study employed in vitro testing methods such as disc diffusion and serial dilution techniques. Simultaneously, antioxidant capacity was evaluated using the DPPH and FRAP methods, while the quantification of total phenolic compounds was performed utilizing the Folin-Ciocalteu method. The findings unveiled notable variations in the antibacterial and antioxidant properties, as well as phenolic content, among the tested plant extracts. Among the seven plants investigated, H. triquetrifolium demonstrated the most potent antibacterial effects against all tested bacterial strains, closely followed by S. dominica. Intriguingly, the methanolic extracts exhibited a higher susceptibility of Gram-positive bacteria in comparison to Gram-negative ones. Additionally, the exploration of antioxidant capacity and polyphenolic content revealed that H. triquetrifolium show cased the highest levels of antioxidant activity and contained the greatest quantity of phenolic compounds (422±20mg GA/g dry extract). Furthermore, a positive linear correlation was established between antioxidant activity and total phenolic content. In summary, the methanolic extracts sourced from H. triquetrifolium exhibit substantial potential as natural reservoirs for effective antibacterial and antioxidant agents.


Cite this article:
Ibrahim Alfarrayeh. The Antibacterial and Antioxidant properties of Methanolic extracts of Selected Medicinal Plants in Jordanian Folk Medicine in Relation to their Phenolic content. Research Journal of Pharmacy and Technology. 2024; 17(5):2247-5. doi: 10.52711/0974-360X.2024.00354

Cite(Electronic):
Ibrahim Alfarrayeh. The Antibacterial and Antioxidant properties of Methanolic extracts of Selected Medicinal Plants in Jordanian Folk Medicine in Relation to their Phenolic content. Research Journal of Pharmacy and Technology. 2024; 17(5):2247-5. doi: 10.52711/0974-360X.2024.00354   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-5-50


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