Author(s): Intani Quarta Lailaty, Peniwidiyanti, Lily Ismaini, Suluh Normasiwi, Sofa Fajriah, Muhammad Rifqi Hariri, Asih Perwita Dewi, Irfan Martiansyah, Prima Wahyu Kusuma Hutabarat, Ahmad Munawir

Email(s): inta009@brin.go.id

DOI: 10.52711/0974-360X.2024.00336   

Address: Intani Quarta Lailaty1*, Peniwidiyanti2,6, Lily Ismaini1, Suluh Normasiwi1, Sofa Fajriah3, Muhammad Rifqi Hariri4, Asih Perwita Dewi4, Irfan Martiansyah1, Prima Wahyu Kusuma Hutabarat4, Ahmad Munawir5
1Research Center for Applied Botany, National Research and Innovation Agency (BRIN), Cibinong, Bogor, West Java, Indonesia, 16911.
2Research Center for Ecology and Ethnobiology, National Research and Innovation Agency (BRIN), Cibinong, Bogor, West Java, Indonesia, 16911.
3Research Center for Pharmaceutical Ingredients and Traditional Medicines, National Research and Innovation Agency (BRIN), Cibinong, Bogor, West Java, Indonesia, 16911.
4Research Center for Biosystematics and Evolution, National Research and Innovation Agency (BRIN), Cibinong, Bogor, West Java, Indonesia, 16911.
5Directorate of Conservation Area Planning, Ministry of Environment and Forestry, Bogor, West Java, Indonesia, 16122.
6Botani Tropika Indonesia Foundation (Botanika), Bogor, West Java, Indonesia, 16112

Published In:   Volume - 17,      Issue - 5,     Year - 2024


ABSTRACT:
The community in Gunung Halimun Salak National Park (GHSNP) uses several plants as alternative medicine in their daily life. Those medicinal plants were sorted from the highest to the lowest value based on Index Cultural Significance (ICS). Thirteen selected native plants from GHSNP were investigated for their antimicrobial and antioxidative potential using DPPH scavenging. Their phytochemical compositions were profiled by phytochemical screening and GC-MS analysis. Staurogyne elongata (ICS= 351) and Blumea balsamifera (ICS= 228) were the most widely used plants in the five hamlets in Cikaniki Resort. Phytochemical screening produced a different color reaction (alkaloids, flavonoids, tannins, and terpenoids) and the presence of foam (saponins) for several species. Plantago major had the highest total phenol and flavonoid content, not significantly different from Turpinia montana. Aquadest extract from Heptapleurum fastigiatum had the highest antioxidant activity (IC50 14.24mg/L). The study showed the highest inhibitory activity for T. montana against Staphylococcus aureus. Meanwhile, the ethanolic extract of S. elongata and Lophatherum gracile inhibited both S. aureus and Escherichia coli's growth. The GC-MS analysis of the ethanolic extracts showed a wide chemical diversity, including 79 compounds from five species, distributed by fatty acids, sesquiterpenes, diterpenes, alkanes, and other organic compounds. Interestingly, GC-MS analysis enabled to identify of several compounds with antioxidant and antibacterial activity in their extracts, such as (-)-Globulol, alpha-cadinol, spathulenol, longifolene, octadecamethyl-cyclononasiloxane, gamma-muurolene, tetracosamethyl-cyclododecasiloxane, and trans-calamenene. The thirteen native species of GHSNP have potential health properties to be utilized and developed as traditional medicine.


Cite this article:
Intani Quarta Lailaty, Peniwidiyanti, Lily Ismaini, Suluh Normasiwi, Sofa Fajriah, Muhammad Rifqi Hariri, Asih Perwita Dewi, Irfan Martiansyah, Prima Wahyu Kusuma Hutabarat, Ahmad Munawir. Ethnopharmacology properties of Medicinal plants used by the community in Gunung Halimun Salak National Park, West Java, Indonesia. Research Journal of Pharmacy and Technology. 2024; 17(5):2121-2. doi: 10.52711/0974-360X.2024.00336

Cite(Electronic):
Intani Quarta Lailaty, Peniwidiyanti, Lily Ismaini, Suluh Normasiwi, Sofa Fajriah, Muhammad Rifqi Hariri, Asih Perwita Dewi, Irfan Martiansyah, Prima Wahyu Kusuma Hutabarat, Ahmad Munawir. Ethnopharmacology properties of Medicinal plants used by the community in Gunung Halimun Salak National Park, West Java, Indonesia. Research Journal of Pharmacy and Technology. 2024; 17(5):2121-2. doi: 10.52711/0974-360X.2024.00336   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-5-32


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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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