Author(s): Sanjeeb K. Kar, Prasanna K. Dixit, Uma S. Mishra, Chowdhury M. Hossain

Email(s): sanjeeb.bit@gmail.com

DOI: 10.52711/0974-360X.2024.00234   

Address: Sanjeeb K. Kar1*, Prasanna K. Dixit2, Uma S. Mishra3, Chowdhury M. Hossain4
1Department of Pharmacy, Sarala Birla University, Ranchi, Jharkhand - 835103, India.

2Department of Zoology, Berhampur University, Berhampur, Odisha - 760007, India.
3Royal College of Pharmacy and Health Sciences, Berhampur, Odisha - 760002, India.
4Department of Pharmaceutical Technology, Maulana Abul Kalam Azad University of Technology, Kolkata, West Bengal - 700064, India.
*Corresponding Author

Published In:   Volume - 17,      Issue - 4,     Year - 2024


ABSTRACT:
The goal of this study was to identify the bioactive principle of the plant Byttneria herbacea (Malvaceae) which has a wide range of traditional therapeutic uses.Column chromatography was used to separate the ethanolic extract of aerial parts of the plant with mobile phase Chloroform: Methanol (5:5). The fraction with Rf 0.62 on TLC with mobile phase Toluene:Ethyl acetate (85:15) imparting bluish color under UV 254 nm was giving the test of Terpenoids. The same fraction was assessed for Antioxidant and Anti-inflammatory activity.Antioxidant activity was performed by measuring the decolourizing activity followed by capturing the unpaired electron from the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) and compared it with the standard anti-oxidant Gallic acid. To test anti-inflammatory activity in an experimental model of acute inflammation, the carrageenan-induced in rat paw edema method was employed.The antioxidant and the anti-inflammatory activities of the Terpenoid fraction were found to be satisfactory.


Cite this article:
Sanjeeb K. Kar, Prasanna K. Dixit, Uma S. Mishra, Chowdhury M. Hossain. Antioxidant and Anti-inflammatory activity of the Terpenoidal fraction of Ethanolic extract of Byttneria herbacea. Research Journal of Pharmacy and Technology.2024; 17(4):1481-5. doi: 10.52711/0974-360X.2024.00234

Cite(Electronic):
Sanjeeb K. Kar, Prasanna K. Dixit, Uma S. Mishra, Chowdhury M. Hossain. Antioxidant and Anti-inflammatory activity of the Terpenoidal fraction of Ethanolic extract of Byttneria herbacea. Research Journal of Pharmacy and Technology.2024; 17(4):1481-5. doi: 10.52711/0974-360X.2024.00234   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-4-8


REFERENCES:
1.    Somkuwar SR. Dongre UJ. Chaudhary RR. Chaturvedi A. In-vitro Screening of an Antioxidant Potential of Byttneria herbacea Roxb. Int. J. Curr. Microbioogy Appl. Sci. 2014; 3:622–629.
2.    Mann & Saunders. Practical Organic Chemistry. British Library Cataloguing in Publication (Longman, London, New York.1960.
3.    Furniss BS. Vogel’s textbook of practical organic chemistry. Longman Scientific & Technical (John Wiley and Sons, New York.1990.
4.    Kar SK. Mishra US. Dixit PK. Nayak S. Isolation of Betulinic Acid from Byttneria herbacea (Malvaceae). Res. J. Pharm. Technol. 2023; 16: 535–538.
5.    Ramakrishnan R. Samydurai P. Thangapandian V. Qualitative phytochemical analysis and in vitro antibacterial activity of Glossocardia bosvallia (Linn. f.) Dc. - An important ayurvedic medicinal herb. Res. J. Pharm. Technol. 2013; 6: 1391–1396.
6.    Shanaida M. Pryshlyak A.  Golembiovska O. Determination of triterpenoids in some lamiaceae species. Res. J. Pharm. Technol. 2018; 11: 3113–3118.
7.    Koleva II. Van Beek TA. Linssen JPH. De Groot A. Evstatieva LN. Screening of plant extracts for antioxidant activity: A comparative study on three testing methods. Phytochem. Anal. 2002; 13: 2015.
8.    Veeru P. Kishor MP. Meenakshi M. Screening of medicinal plant extracts for antioxidant activity. J. Med. Plants Res. 2009; 3: 608–612.
9.    Krishna K. Karuppuraj V. Perumal VK. Antioxidant activity and Folic acid content in indigenous isolates of Ganoderma lucidum. Asian J. Pharm. Ana. 2016; 6: 213–215.
10.    Vignesh B. Tamil SE. Srinivasan A. Nandhini AS. Punica granatum root (s): Phytocompounds analysis. Anti-oxidant and Anti-microbial activity. Asian J. Pharm. Ana. 2019; 9: 123–127.
11.    Jadhav GB. Saudagar RB. Free radical Scavenging and Antioxidant Activity of Punica granatum Linn. Asian J. Res. Pharm. Sci. 2014; 4: 5.
12.    Malathi R. Cholarajan A. Antioxidant activity of extract from the leaves of Tylophora asthmatica. J. Microbiol. Antimicrob. 2012; 4: 80–82.
13.    Balamurugan Gunasekaran P. Muralidharan A. Pandiselvi PA. Preliminary Phytochemical screening and Anti oxidant activities of Ethanolic extract of Caesalpinia sappan Linn. . Res. J. Pharm. Tech. 2008; 1: 179–181.
14.    Parejo I. et al. Investigation of Bolivian plant extracts for their radical scavenging activity and antioxidant activity. Life Sci. 2003;73:1667–1681.
15.    Valli G. Jeyalakshmi M. Preliminary Phytochemical and Antioxidant Study of Odina woodier Leaf Extract. Asian J. Pharm. Res. 2012; 2: 153–55.
16.    Winter CA. Risley EA.  Nuss GW. Carrageenin-Induced Edema in Hind Paw of the Rat as an Assay for Antiinflammatory Drugs. Exp. Biol. Med. 1962; 111: 544–547.
17.    Saravana KA. Ramaswamy NM. Anti-Inflammatory activity of Sesbania Grandiflora (Fabaceae). Res. J. Pharm. Tech. 2009; 2: 214–215.
18.    Venkateshwarlu G. Kanakam VB. Sravan PM.Bhaskar J. Suvarna Devi P. Ramchander T. Effects of Anti-Inflammatory Activity of Mimosa pudica. Asian J. Pharm. Res. 2011; 1: 69–71.
19.    Bhaskar VH. Sangameswaran B. Balakrishnan N. Panda AB. Navin RR. Sathish A. Screening of Analgesic and Anti-inflammatory Activity of Hydroalcohol Extract of Sida (Indian) Species Root. Res. J. Pharm. Tech. 2008; 1: 287–289.
20.    Bachhav RS. Buchake VV. Saudagar RB. Analgesic and Anti-Inflammatory Activities of Anthocephalus Cadamba Roxb. Leaves in Wistar Rats. Res. J. Pharm. Tech. 2009; 2: 164–67.
21.    Sheshadri SD. Velmurugan C. Ramakrishnan BV. Anti-Inflammatory Activity of Ethanolic and Acetone Extracts of Bauhnia Variegate. Res. J. Pharm. Tech. 2009; 2: 409–11.


Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags


Not Available