Author(s):
Sanjeeb K. Kar, Prasanna K. Dixit, Uma S. Mishra, Chowdhury M. Hossain
Email(s):
sanjeeb.bit@gmail.com
DOI:
10.52711/0974-360X.2024.00234 
Address:
Sanjeeb K. Kar1*, Prasanna K. Dixit2, Uma S. Mishra3, Chowdhury M. Hossain4
1Department of Pharmacy, Sarala Birla University, Ranchi, Jharkhand - 835103, India.
2Department of Zoology, Berhampur University, Berhampur, Odisha - 760007, India.
3Royal College of Pharmacy and Health Sciences, Berhampur, Odisha - 760002, India.
4Department of Pharmaceutical Technology, Maulana Abul Kalam Azad University of Technology, Kolkata, West Bengal - 700064, India.
*Corresponding Author
Published In:
Volume - 17,
Issue - 4,
Year - 2024
ABSTRACT:
The goal of this study was to identify the bioactive principle of the plant Byttneria herbacea (Malvaceae) which has a wide range of traditional therapeutic uses.Column chromatography was used to separate the ethanolic extract of aerial parts of the plant with mobile phase Chloroform: Methanol (5:5). The fraction with Rf 0.62 on TLC with mobile phase Toluene:Ethyl acetate (85:15) imparting bluish color under UV 254 nm was giving the test of Terpenoids. The same fraction was assessed for Antioxidant and Anti-inflammatory activity.Antioxidant activity was performed by measuring the decolourizing activity followed by capturing the unpaired electron from the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH) and compared it with the standard anti-oxidant Gallic acid. To test anti-inflammatory activity in an experimental model of acute inflammation, the carrageenan-induced in rat paw edema method was employed.The antioxidant and the anti-inflammatory activities of the Terpenoid fraction were found to be satisfactory.
Cite this article:
Sanjeeb K. Kar, Prasanna K. Dixit, Uma S. Mishra, Chowdhury M. Hossain. Antioxidant and Anti-inflammatory activity of the Terpenoidal fraction of Ethanolic extract of Byttneria herbacea. Research Journal of Pharmacy and Technology.2024; 17(4):1481-5. doi: 10.52711/0974-360X.2024.00234
Cite(Electronic):
Sanjeeb K. Kar, Prasanna K. Dixit, Uma S. Mishra, Chowdhury M. Hossain. Antioxidant and Anti-inflammatory activity of the Terpenoidal fraction of Ethanolic extract of Byttneria herbacea. Research Journal of Pharmacy and Technology.2024; 17(4):1481-5. doi: 10.52711/0974-360X.2024.00234 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-4-8
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