Author(s): Alfin Syahrian Dwi Nugraha1, Paula Mariana Kustiawan1*, Deasy Nur Chairin Hanifa1, Irfan Muris Setiawan

Email(s): pmk195@umkt.ac.id

DOI: 10.52711/0974-360X.2024.00283   

Address: Alfin Syahrian Dwi Nugraha1, Paula Mariana Kustiawan1*, Deasy Nur Chairin Hanifa1, Irfan Muris Setiawan2
1Faculty of Pharmacy, Universitas Muhammadiyah Kalimantan Timur, Jl. Juanda No. 15 Samarinda, East Kalimantan, Indonesia
2Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Indonesia
*Corresponding Author

Published In:   Volume - 17,      Issue - 4,     Year - 2024


ABSTRACT:
Since the beginning of human history, bee honey has been used by humans. However, there are also other bee products such as bee pollen (BP), royal jelly, propolis, and beeswax. Previous research has identified that pollen contains amino acids, lipids, flavonoids, micronutrients and many fat-soluble vitamins such as vitamins A, E and D, as well as water-soluble vitamins such as vitamins B1, B2, B6 and C. The objective of this study is to formulate bee pollen as effervescent tablet. The method in this study used alkaline granulation which requires an oven process for 24 hours and the use of a combination of sodium bicarbonate with citric acid. Three formulas were optimized in this study. The stability test results showed that formula number 3 has an average moisture content of 0.5696±0.6154%, and average flow rate of 0.67±0.02054 g/sec, the average compressibility in formula number 1 is 0.046±0.0452%. Overall, it is also known that formula number 2 has the smallest dissolution time compared to other formulations. The effect of the combination of citric acid and sodium bicarbonate used in the formulation of effervescent tablets from bee pollen on the physical quality of the tablets, namely friability, hardness, and dissolving time, the higher levels of citric acid and sodium bicarbonate used do not have a significant effect on friability, hardness, and time dissolving effervescent tablets from bee pollen from kelulut bees (Trigona sp).


Cite this article:
Alfin Syahrian Dwi Nugraha1, Paula Mariana Kustiawan1*, Deasy Nur Chairin Hanifa1, Irfan Muris Setiawan. Formulation of Effervescent Tablet from Kelulut Bee (Trigona sp.) Pollen from East Kalimantan. Research Journal of Pharmacy and Technology.2024; 17(4):1784-8. doi: 10.52711/0974-360X.2024.00283

Cite(Electronic):
Alfin Syahrian Dwi Nugraha1, Paula Mariana Kustiawan1*, Deasy Nur Chairin Hanifa1, Irfan Muris Setiawan. Formulation of Effervescent Tablet from Kelulut Bee (Trigona sp.) Pollen from East Kalimantan. Research Journal of Pharmacy and Technology.2024; 17(4):1784-8. doi: 10.52711/0974-360X.2024.00283   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-4-57


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