Author(s): Grishma Patel, Rajnikant Maradia, Tejal Soni, Bhanubhai Suhagia, Dhananjay Meshram

Email(s): grishmapatel17588@gmail.com

DOI: 10.52711/0974-360X.2024.00254   

Address: Grishma Patel1*, Rajnikant Maradia1, Tejal Soni1, Bhanubhai Suhagia1, Dhananjay Meshram2
1Department of Quality Assurance, Faculty of Pharmacy, Dharamsinh Desai University, Nadiad.
2Department of Quality Assurance, Pioneer Pharmacy College, GTU, Ahmedabad.
*Corresponding Author

Published In:   Volume - 17,      Issue - 4,     Year - 2024


ABSTRACT:
The result of pharmaceutical industry research for the new class and the new combination of drugs for the treatments of diabetes is the newly approved combination of Remogliflozin etabonate (RGE) and Teneligliptin Hydrobromide hydrate (TG). For the quality control of this formulation, the smart, reproducible and non-sophisticated spectroscopic techniques were developed by modification of UV spectra. The proposed methods exhibited Beer’s law in the range of 10 to 60µg/ml and 5 to 30µg/ml for RGE and TG correspondingly. The mean percentage recovery was found to be in the range of 98.60 to 101.55 for RGE and 99.87 to 100.21 for TG. Further, both analytes were quantified from the formulation using proposed spectroscopic methods with high accuracy. The suggested technique is simple, accurate and reproducible, hence could be used for regular quality control of formulation consisting of RGE and TG. The developed method can be used for analysis of stability samples and routing quality control evaluation in tablet formulation.


Cite this article:
Grishma Patel, Rajnikant Maradia, Tejal Soni, Bhanubhai Suhagia, Dhananjay Meshram. Development and Validation of UV Spectrophotometric Method for Simultaneous Estimation of some SGLT-2 and DPP-4 inhibitor in Bulk and Pharmaceutical Dosage Form. Research Journal of Pharmacy and Technology.2024; 17(4):1606-0. doi: 10.52711/0974-360X.2024.00254

Cite(Electronic):
Grishma Patel, Rajnikant Maradia, Tejal Soni, Bhanubhai Suhagia, Dhananjay Meshram. Development and Validation of UV Spectrophotometric Method for Simultaneous Estimation of some SGLT-2 and DPP-4 inhibitor in Bulk and Pharmaceutical Dosage Form. Research Journal of Pharmacy and Technology.2024; 17(4):1606-0. doi: 10.52711/0974-360X.2024.00254   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-4-28


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