Author(s): Priyanka R, Manjunatha Reddy A. H, Sumathra Manokaran, Raje Siddiraju Upendra

Email(s): ahmanjunatha@rvce.edu.in , 1789priyanka@gmail.com , sumathram@rvce.edu.in , rsupendra.raju@gmail.com

DOI: 10.52711/0974-360X.2024.00213   

Address: Priyanka R1, Manjunatha Reddy A. H1*, Sumathra Manokaran1, Raje Siddiraju Upendra2
1Department of Biotechnology, RV College of Engineering, Bangalore - 560059, (Karnataka) India.
2School of Multidisciplinary Studies, Reva University, Bengaluru, India.
*Corresponding Author

Published In:   Volume - 17,      Issue - 3,     Year - 2024


ABSTRACT:
Curcuma aromatica is a species of the Curcuma genus of flowering plants in the ginger family, Zingiberaceae. It is commonly known as wild turmeric, and is native to Southeast Asia, particularly India and Sri Lanka. It is traditionally used in Ayurvedic and other traditional systems for its anti-inflammatory, antioxidant, and antimicrobial properties. In the present research study, the antiproliferative activity was assessed for C.aromatica rhizome extract, rhizome essential oil and leaf oil individually. The results clearly demonstrated the efficacy of C.aromatica extracts and essential oils as a antiproliferative effect towards MDA-MB231, the Breast cancer cell line. The reduction in the cell viability of the breast cancer cell lines on treating with the extracts and essential oils individually can be attributed to Curcumin, Demethoxycurcumin and Bisdemethoxycurcumin and unique odour defining components such as cedrene, Xanthorrhizol, camphor, Germacrone, Isofuranogermacrone and 1,8-cineole. The study clearly demonstrates the antiproliferative effects of C.aromatica.


Cite this article:
Priyanka R, Manjunatha Reddy A. H, Sumathra Manokaran, Raje Siddiraju Upendra. Antiproliferative effects of C.aromatica Extracts and Essential oils in MDA-MB231 as a Breast Cancer Cell Line. Research Journal of Pharmacy and Technology. 2024; 17(3):1352-5. doi: 10.52711/0974-360X.2024.00213

Cite(Electronic):
Priyanka R, Manjunatha Reddy A. H, Sumathra Manokaran, Raje Siddiraju Upendra. Antiproliferative effects of C.aromatica Extracts and Essential oils in MDA-MB231 as a Breast Cancer Cell Line. Research Journal of Pharmacy and Technology. 2024; 17(3):1352-5. doi: 10.52711/0974-360X.2024.00213   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-3-64


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