Author(s): Hawaz Shewatetak, Raghavendra Yarlagadda, Kotaiah Silakabattini, Ramanji Reddy Tatiparthi, Venkateswara Rao Jallepalli

Email(s): venkateswararao.j92@gmail.com

DOI: 10.52711/0974-360X.2024.00198   

Address: Hawaz Shewatetak1, Raghavendra Yarlagadda1, Kotaiah Silakabattini2, Ramanji Reddy Tatiparthi3, Venkateswara Rao Jallepalli4*
1School of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia.
2Komar University of Sciences and Technology, Kularaisi, Iraq.
3Department of Pharmaceutics, Veda College of Pharmacy, Addanki, AP, India - 523265.
4MB School of Pharmaceutical Sciences, Mohan Babu University, Tirupati, India - 517102.
*Corresponding Author

Published In:   Volume - 17,      Issue - 3,     Year - 2024


ABSTRACT:
Background: In the 21st century, low- and middle income, war prone and drought-prone areas in developing nations have seen a fast rise in the prevalence of chronic liver disease (CLD). An estimated 240 million people worldwide are infected with HIV, and 780,000 deaths are attributed to it each year, according to the World Health Organization (WHO). Objective: We want to assess the efficacy of in-hospital care for CLD patients by verifying and evaluating current management practices. Method: A retrospective descriptive study of patients with chronic liver disease who were followed up on at Debre Berhan Hospital between July 2018 and January 2021 was conducted. Results: Out of a total of 209 patients tested, 127 (or 60.74%) were males aged 41.44±12.89 of years. Ascites complications were presented in over 44% of cases. Using the laboratory data, 65 patients (31.10%) and 71 patients (33.97%) were found to have abnormally high AST and ALT values on LFTs testing. AUROC analysis was carried out with a 95% CI for Child-Pugh of 0.61 (0.53-0.75, P=0.14), MELD 0.75 (0.63-0.72, P=0.26), and ALBI 0.53 (0.31-0.54, P=0.29). Conclusion: Based on the predictive data, 87 (41.63%) patients were successfully treated and released, whereas 57(27.27%) were recommended for further care, and 47 died due to co-morbid conditions. Although, the study period coincides with the COVID-19 pandemic, more analysis of the obtained data is necessary.


Cite this article:
Hawaz Shewatetak, Raghavendra Yarlagadda, Kotaiah Silakabattini, Ramanji Reddy Tatiparthi, Venkateswara Rao Jallepalli. Clinical Management practice and Therapeutic Outcomes of Chronic Liver Disease patients in the Conflicted area of North Ethiopia. Research Journal of Pharmacy and Technology. 2024; 17(3):1267-1. doi: 10.52711/0974-360X.2024.00198

Cite(Electronic):
Hawaz Shewatetak, Raghavendra Yarlagadda, Kotaiah Silakabattini, Ramanji Reddy Tatiparthi, Venkateswara Rao Jallepalli. Clinical Management practice and Therapeutic Outcomes of Chronic Liver Disease patients in the Conflicted area of North Ethiopia. Research Journal of Pharmacy and Technology. 2024; 17(3):1267-1. doi: 10.52711/0974-360X.2024.00198   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-3-49


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