Author(s): Kumudini R Pawar, Priyanka G Kale, Madhuri S Nalawade, Tejashree Patil, Shruti Gaikwad

Email(s): kumudinipawar30@gmail.com

DOI: 10.52711/0974-360X.2024.00186   

Address: Kumudini R Pawar, Priyanka G Kale, Madhuri S Nalawade, Tejashree Patil, Shruti Gaikwad
Abhinav Education Society's, College of Pharmacy (B.Pharm), Narhe, Pune – 41.
*Corresponding Author

Published In:   Volume - 17,      Issue - 3,     Year - 2024


ABSTRACT:
The purpose of this study was to compare the herbal drugs which are used traditionally with commonly used synthetic drugs for the treatment of intestinal worm infestation. The experiment was conducted using adult Indian earthworms (Pheretima Posthuma) owing to their anatomical and physiological similarity to human intestinal parasites, making it convenient for the evaluation of anthelmintic compounds in a laboratory setting. As a control sample and preparation of samples normal saline solution was used. Various concentrations of both herbal and synthetic drugs were tested and result was obtained in the terms of time of paralysis and time of death in minutes. All the drugs show different time of paralysis and death of worms. In this study we took herbal powders without any extraction process or chemical process done on it.


Cite this article:
Comparative Study of Herbal drugs and Synthetic drugs used for treatment of Intestinal Worm Infestation. Comparative Study of Herbal drugs and Synthetic drugs used for treatment of Intestinal Worm Infestation. Research Journal of Pharmacy and Technology. 2024; 17(3):1196-9. doi: 10.52711/0974-360X.2024.00186

Cite(Electronic):
Comparative Study of Herbal drugs and Synthetic drugs used for treatment of Intestinal Worm Infestation. Comparative Study of Herbal drugs and Synthetic drugs used for treatment of Intestinal Worm Infestation. Research Journal of Pharmacy and Technology. 2024; 17(3):1196-9. doi: 10.52711/0974-360X.2024.00186   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-3-37


REFERENCES:
1.    Nisha PV and et al. Anthelmintic activity of Pyrostegia venusta using Pheretima posthuma. International Journal of Pharmaceutical Sciences and Drug Research. 2012 July 4(3): 205-208.
2.    Das SS, Dey M, Ghosh AK. Determination of Anthelmintic Activity of the Leaf and Bark Extract of Tamarindus Indica Linn. Indian Journal of Pharmaceutical Sciences. 2011 Jan-Feb 73(1): 104–107. doi: 10.4103/0250-474X.89768
3.    Mahaparale S, Banju D. Recent Analytical Methods of Anti-Helmintic Agents. Asian J. Pharm. Res. 2019; 9(3):209-218. doi: 10.5958/2231-5691.2019.00035.2
4.    George B, Kousalya P. In Vitro Anthelmintic Efficacy of Amaranthus Dubius, Basella Alba and Cleome Gynandra. Der Pharma Chemica, 2018, 10(6): 142-148.
5.    Ghausia I, Nasreen J. Anthelmintic activity of Majoon Sarakhs on Earthworm. Bangladesh Journal of Medical Science. 2020 October 19(4):659-669. doi:10.3329/bjms.v19i4.46622
6.    Nadkarni KM. Indian Materia Medica. Popular Pakashan, Mumbai. India. 1976
7.    Maciej G. and et.al.  Evaluation of Anthelmintic Activity and Composition of Pumpkin (Cucurbita pepo L.) Seed Extracts-In Vitro and in Vivo Studies. International Journal of Molecular Science. 2016 September 17(9):1456-1460. doi:10.3390/ijms17091456
8.    Erol A and et al. Evaluation of the anthelmintic activity of pumpkin seeds (Cucurbita maxima) in mice naturally infected with Aspiculuris tetraptera. Journal of Pharmacognosy and Phytotherapy. 2015 September 7(9):189-193. doi: 10.5897/JPP2015.0341
9.    Raul SK and et. al. Comparative Evaluation of Anthelmintic Potential of Cucurbita maxima Seeds, Moringa oleifera Seeds and Solanum surattense Fruits. Res. J. Pharmacognosy & Phytochem. 2014; 6(4): 187-189.
10.    Patil P and et.al. , In Vitro Anthelmintic Activity of Various Herbal Plants Extracts against Pheritima posthuma. Research J. Pharmacognosy and Phytochemistry 2010; 2(3): 234-237.
11.    Aashiq MM, and Keziah N. Anthelmintic Activity of Panchachurnam: An Ayurvedic Polyherbomineral Formulation. Res. J. Pharmacognosy and Phytochem. 2017; 9(4): 210-214. doi: 10.5958/0975-4385.2017.00038.3
12.    27. Singh AK, and et. al. In-vitro Anthelmintic Activity of Stem Bark Extracts of Saraca indica Roxb. against Pheretima posthuma. Asian J. Research Chem.  2014 February; 7(2):141-143.
13.    Ramjan Ali MD, and et. al. Assessment of anthelmintic potential of Averrhoa bilimbi, Clerodendrum viscosum and Drynaria quercifolia: as an alternative source for anthelmintics. Research J. Pharmacognosy and Phytochemistry 2013; 5(4):178-181.
14.    Sengupta R, Banik J. Comparative Studies on Anthelmintic Potential of Cucurbita maxima (Pumpkin) Seeds and Carica Papaya (Papaya) Seeds. International Journal of Research in Ayurveda and Pharmacy. 2013 4(4):530-532. doi:10.7897/2277-4343.04415
15.    Yadav R, Agarwala M. Phytochemical Analysis of Some Medicinal Plants. Journal of Phytology. 2011 3(12):10-14.
16.    Khade VM and et al. Formulating Pharmacognostic and Physicochemical Insights of Polyherbal Vermifuge Formulation. Asian J. Pharm. Tech. 2021; 11(1):36-40. doi: 10.5958/2231-5713.2021.00006.4
17.    Shiba S and et. al. Phytochemical Screening and In-vitro Athelmintic activity of Seed Extracts of Plants Carum carvi of Family Apiaceae. Asian J. Res. Pharm. Sci. 2016; 6(4): 246-254.
18.    Hemamalini k and et al. Anthelmintic Activity of Methanolic Leaf Extract Of Sophora Interrupta. International Research Journal of Pharmacy. 2013 September 4(8):148-150. doi: 10.7897/2230-8407.04828
19.    Shivan NH, Mohammed SS. In-Vitro Anthelmentic Efficacy of Pumpkin Seed Oil (Cucurbita Pepo) on Toxocariosis (Toxocara Cati). Exploratory Animal and Medical Research. 2020 October 10(2):154-161
20.    Gupta N and et. al. Anthelmintic Activity of Latex of Carica papaya. Research J. Pharmacology and Pharmacodynamics. 2009; 1(2): 85-86.
21.    Jeek J and et al. The Effect of Pumpkin Seed Cake and Ground Cloves (Syzygium aromaticum) Supplementation on Gastrointestinal Nematode Egg Shedding in Sheep.Parasite. 2021 December 28:78. doi: 10.1051/parasite/2021076
22.    Sundeep Kumar HK and et.al. Evaluation of Anthelmintic Activity of Bambusa arundinacea. Asian J. Pharm. Tech. 2012 June, 2(2):62-63.
23.    Manjula RR and et.al. In Vitro Anthelmintic Activity of Aqueous and Methanolic Leaf Extract of Tephrosia Purpurea Linn. International Journal of Research Pharmacy and Chemistry. 2013 January 3(1):12-14.
24.    Sree VK and et al. In vitro screening of Macrotyloma Uniflorum Extracts for Antioxidant and Anthelmintic Activities.  Journal of Pharmacognosy and Phytochemistry 2014 September; 3(4):6-10.
25.    Joshi UP and Wagh RD. In-Vitro Anthelmintic Activity of Ehretia Laevis Bark on Indian Adult Earthworm. International Journal for Pharmaceutical Research Scholars. 2018 November 7(4):22-30. doi:10.31638/IJPRS.V7.I4.00012
26.    Sutnga I and et al. Anthelmintic and Analgesic Activities of Trachyspermum Khasianum H. Wolff. Journal of Pharmacopuncture. 2020 December 23(4):230-236. doi: 10.3831/KPI.2020.23.4.230.
27.    Dubey RD, and et.al. In Vitro Comparative Studies of Anthelmintic Activity of Allium sativum and Ficus religiosa. Research J. Science and Tech. 2010; 2(4): 84-86.
28.    Rastogi T, and et. al. Comparative Studies on Anthelmintic Activity of Moringa Oleifera and Vitex Negundo. Asian J. Research Chem. 2009 June; 2(2):181-182.




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