Author(s): V. H. Karambelkar, Neha Shankar Sheety, Ganesh Throat, Madhuranjan Vatsa, Shiju Sebastian, Sudhir Patil

Email(s): vhkarambelkar@outlook.com

DOI: 10.52711/0974-360X.2024.00152   

Address: V. H. Karambelkar1*, Neha Shankar Sheety2, Ganesh Throat3, Madhuranjan Vatsa4, Shiju Sebastian5, Sudhir Patil6
1,3Department of Medicine, Krishna Vishwa Vidyapeeth Deemed to be University, Karad, Satara, Maharashtra, India.
2Department of Ophthalmology, Krishna Vishwa Vidyapeeth,
Deemed to be University, Karad, Satara, Maharashtra, India.
4Director, Akhildev IPR and Research Services, Greater Noida, UP, India.
5Associate Professor, Christ (Deemed to be University), India.
6Bharati Vidyapeeth College of Pharmacy, Palus, Maharashtra, India.
*Corresponding Author

Published In:   Volume - 17,      Issue - 3,     Year - 2024


ABSTRACT:
Prior to the development of the ophthalmoscope, macular oedema remained mostly unknown. Macular oedema is caused by fluid buildup in the retinal layers around the fovea. It causes vision loss by changing the functional cell connection in the retina and stimulating an inflammatory reparative response. The clinical profile, aetiology, and varied types of Macular Oedema are hence the focus of research, and also to investigate the aetiology of macular oedema as well as the various forms of macular oedema in patients attending Krishna Hospital in Karad. The male to female ratio among the 60 participants was 2.53:1. Macular oedema is the major cause for loss in vision which is common vitreo retinal diseases, with diabetes being the most prevalent cause (35% of cases) in our study. Its early detection and treatment are critical for preventing blindness. It is consequently critical to understand the aetiology, pattern, and chronicity of macular oedema in order to customize treatment and monitor response to it.


Cite this article:
V. H. Karambelkar, Neha Shankar Sheety, Ganesh Throat, Madhuranjan Vatsa, Shiju Sebastian, Sudhir Patil. Clinical Study Macular Oedema. Research Journal of Pharmacy and Technology. 2024; 17(3):986-0. doi: 10.52711/0974-360X.2024.00152

Cite(Electronic):
V. H. Karambelkar, Neha Shankar Sheety, Ganesh Throat, Madhuranjan Vatsa, Shiju Sebastian, Sudhir Patil. Clinical Study Macular Oedema. Research Journal of Pharmacy and Technology. 2024; 17(3):986-0. doi: 10.52711/0974-360X.2024.00152   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-3-3


REFERENCES:
1.    Noma H., Yasuda K. and Shimura M. Involvement of cytokines in the pathogenesis of diabetic macular edema. International Journal of Molecular Sciences. 2021; 22(7): 3427. doi: 10.3390/ijms22073427.
2.    Lobo C. Pseudophakic cystoid macular edema. Ophthalmologica. 2012; 227(2):61-67. doi: 10.1159/000331277.
3.    Jia HQ et al. Diagnostic value of optical coherence tomography for diabetic macular edema. International Journal of Ophthalmology. 2008; 8(11):2248-50.
4.    Cunha-Vaz J. Mechanisms of retinal fluid accumulation and blood-retinal barrier breakdown. Developments in Ophthalmology. 2017; 58:11-20, doi: 10.1159/000455265.
5.    Koronis S. et al. Update in treatment of uveitis macular edema. Drug Design, Development and Therapy. 2019; 13: 667-680. doi: 10.2147/DDDT.S166092.
6.    Soliman, W. et al. Local retinal sensitivity in relation to specific retinopathy lesions in diabetic macular oedema. Acta Ophthalmologica. 2012; 90(3):248-53 doi: 10.1111/j.1755-3768.2010.01912.x.
7.    Schmidt-Erfurth U. et al. Guidelines for the management of diabetic macular edema by the European Society of Retina Specialists (EURETINA). Ophthalmologica. 2017; 237(4):185-222. doi: 10.1159/000458539.
8.    Wu Q. et al. Detection of morphologic patterns of diabetic macular edema using a deep learning approach based on optical coherence tomography images. Retina, 2021; 41(5): 1110-1117. doi: 10.1097/IAE.0000000000002992.
9.    Shirke DB et al.. Clinical study of paediatric ocular trauma and its assessment with paediatric ocular trauma score. Research Journal of Pharmacy and Technology 2023; 16(5):2359-3. doi: 10.52711/0974-360X.2023.00388
10.    Rogers SL et al. Natural history of branch retinal vein occlusion: an evidence-based systematic review. Ophthalmology. 2010; 117(6): 1094-1101.e5. doi: 10.1016/j.ophtha.2010.01.058.
11.    Bin Hwang H, Jee D, and Kwon JW. Characteristics of diabetic macular edema patients with serous retinal detachment. Medicine (United States), 2019; 98(51): e18333. doi: 10.1097/MD.0000000000018333.
12.    Rhoades W. Management of macular edema due to central retinal vein occlusion - The role of aflibercept. Taiwan Journal of Ophthalmology. 2017; 7(2): 70–76. doi: 10.4103/tjo.tjo_9_17.
13.    Shalchi Z. Anti-vascular endothelial growth factor for macular oedema secondary to branch retinal vein occlusion. Cochrane Database of Systematic Reviews. 2020; 7(7): CD009510. doi: 10.1002/14651858.CD009510.pub3.
14.    Pande R. How diabetes affects your eyes. Ophthalmology Times, 2015.
15.    Wang N. et al. Epidemiology of diabetic macular edema in patients with type 2 diabetes in the Beixinjing District of Shanghai. Chinese Journal. Ophthalmology. 2007; 43(7): 626-30.
16.    Nassar GA. Macular vascular features of different types of diabetic macular edema using ocular coherence tomography angiography- a comparative study. International Journal of Retina and Vitreous. 2023; 9(1):1–11. doi: 10.1186/s40942-023-00469-6.
17.    Zou D. Jawaid I and Amoaku WM. Retrospective analysis of treatment patterns in pseudophakic diabetic macular oedema eyes treated with anti-VEGF. Journal of Ophthalmology. 2021, 9967831. doi: 10.1155/2021/9967831.
18.    Sangroongruangsri S. Comparative efficacy of bevacizumab, ranibizumab, and aflibercept for treatment of macular edema secondary to retinal vein occlusion: a systematic review and network meta-analysis. Expert Review of Clinical Pharmacology. 2018; 11(9): 903-916. doi: 10.1080/17512433.2018.1507735.
19.    Singh L. Prevalence and pattern of macular edema in diabetes. Journal of Medical Science and clinical Research. 2016; 4(11):  13891-7, doi: 10.18535/jmscr/v4i11.63.
20.    Lindner M. Association of periodontitis and diabetic macular edema in various stages of diabetic retinopathy. Clinical Oral Investigations. 2022; 26(1): 505–512. doi: 10.1007/s00784-021-04028-x.
21.    Ichiyama Y. The effectiveness of vitrectomy for diffuse diabetic macular edema may depend on its preoperative optical coherence tomography pattern. Graefe's Archive for Clinical and Experimental Ophthalmology. 2016; 254(8): 1545-1551. doi: 10.1007/s00417-015-3251-4.

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