ABSTRACT:
This comprehensive literature review delves into the multifaceted realm of preventing, controlling, and treating tobacco use addiction. Synthesizing a vast array of scholarly works, the study navigates through the complexities of tobacco dependence, shedding light on diverse strategies employed globally. Pharmacological interventions, such as nicotine replacement therapy and emerging medications, are scrutinized alongside non-pharmacological approaches, including health education programs, psychological counseling, and cognitive-behavioral therapy. The review underlines the imperative to comprehend the neurobiology of tobacco addiction, emphasizing its pivotal role in crafting targeted and individualized treatments. By amalgamating evidence-based practices, the study contributes to the advancement of knowledge in the ongoing quest for efficacious prevention and treatment strategies for tobacco use addiction. The review study investigates the role of health institutions and government agencies in collaborating to control tobacco use, highlighting the variation in smoking cessation policies across countries and the legal counteraction of the tobacco industry's aggressive marketing. In detailing the treatment landscape, the review explores both pharmacological and non-pharmacological interventions. Pharmacologically, nicotine replacement therapy, prescription medications, and novel drugs like Varenicline are expounded upon. Non-pharmacological approaches encompass health education programs, psychological counseling, cognitive-behavioral therapy, and psychosocial support, underscoring the importance of counseling as a non-pharmacological intervention. The study concludes by discussing the ongoing trials for nicotine vaccines and cannabinoid CB1 receptor antagonists as promising avenues for future pharmacotherapeutic interventions. Overall, this literature review consolidates diverse insights to provide a holistic understanding of tobacco use addiction and its comprehensive management.