Author(s):
Md Tamijur Rahman, Uzma Hismat, Ranjan Tripura, Paromita Dutta Choudhury, Bikash Debnath, Suvakanta Das
Email(s):
phtamijurr@gmail.com
DOI:
10.52711/0974-360X.2024.00142 
Address:
Md Tamijur Rahman1,3*, Uzma Hismat1, Ranjan Tripura1, Paromita Dutta Choudhury1, Bikash Debnath2, Suvakanta Das1
1Regional Institute of Pharmaceutical Science and Technology (RIPSAT), Agartala Tripura 799005, India.
2Institute of Pharmacy, Assam Don Bosco University, Tapesia, Sonapur, Assam 782402, India.
3Department of Pharmaceutical Sciences, Assam University, Silchar 788011, India.
*Corresponding Author
Published In:
Volume - 17,
Issue - 2,
Year - 2024
ABSTRACT:
This review aims to compile the current literature with a perspective on the role of natural polymers or polysaccharides in mucoadhesive drug delivery systems. Natural polymers are basically polysaccharides, biocompatible, non-toxic, stable, and economical. Polymers play an important role as excipients in designing the dosage form and influence drug release without any side effects. Natural polymers are of growing interest in the utilization of mucosal drug delivery as a novel technique due to their ability to interact with the mucosal layer of the body, improve the effectiveness of the drug, and prolong the residence time of the dosage form at the site of absorption. The bioadhesive polymers can exert control over the rate and extent of drug release and are selected in the formulation of mucoadhesive drug delivery systems. This review article discusses several aspects of mucoadhesive drug delivery, including the mechanism of mucoadhesion, mucus layer, and mucoadhesive polymers, with special reference to natural-based polysaccharides, as well as their applications and roles in different formulations developed by using polysaccharides in various dosage forms.
Cite this article:
Md Tamijur Rahman, Uzma Hismat, Ranjan Tripura, Paromita Dutta Choudhury, Bikash Debnath, Suvakanta Das. Overview on Natural Polymers: A Promising Pharmaceutical excipient in Mucoadhesive Drug Delivery System. Research Journal of Pharmacy and Technology. 2024; 17(2):915-9. doi: 10.52711/0974-360X.2024.00142
Cite(Electronic):
Md Tamijur Rahman, Uzma Hismat, Ranjan Tripura, Paromita Dutta Choudhury, Bikash Debnath, Suvakanta Das. Overview on Natural Polymers: A Promising Pharmaceutical excipient in Mucoadhesive Drug Delivery System. Research Journal of Pharmacy and Technology. 2024; 17(2):915-9. doi: 10.52711/0974-360X.2024.00142 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-2-70
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