Author(s):
Yudhytha A. Quraisyin, Antonia M. I. Saktiawati, Ronny Martien
Email(s):
ronnymartien@ugm.ac.id
DOI:
10.52711/0974-360X.2024.00924 
Address:
Yudhytha A. Quraisyin1, Antonia M. I. Saktiawati2, Ronny Martien1,3*
1Biotechnology Study Program, Graduate School, Universitas Gadjah Mada, Yogyakarta, 55281 Indonesia.
2Department of Internal Medicine, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia.
3Departement of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia.
*Corresponding Author
Published In:
Volume - 17,
Issue - 12,
Year - 2024
ABSTRACT:
Efficient and cost-effective UV spectrophotometric techniques have been devised using methanol and phosphate buffer pH 7.4 to quantify Rifampicin concentrations in the Self Nanoemulsifying Drug Delivery System (SNEDDS), as shown by the drug loading efficiency. Rifampicin has a peak wavelength of 474nm with a concentration of 10-50µg/mL. The relationship between the concentration and the absorbance is linear, as shown by a high correlation value (r) of 0.9998. The average percent recovery of Rifampicin falls between the range of 99.138% to 101.349%. The approach devised is suitable for analyzing Rifampicin in nanoparticle formulations.
Cite this article:
Yudhytha A. Quraisyin, Antonia M. I. Saktiawati, Ronny Martien. Development of a UV Spectrophotometric Method for Validating Drug Loading Efficiencyof SNEDDS Rifampicin. Research Journal Pharmacy and Technology. 2024;17(12):6098-1. doi: 10.52711/0974-360X.2024.00924
Cite(Electronic):
Yudhytha A. Quraisyin, Antonia M. I. Saktiawati, Ronny Martien. Development of a UV Spectrophotometric Method for Validating Drug Loading Efficiencyof SNEDDS Rifampicin. Research Journal Pharmacy and Technology. 2024;17(12):6098-1. doi: 10.52711/0974-360X.2024.00924 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-12-61
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