Author(s): Kanittada Thongkao, Pimporn Thongmuang, Robert W. Owen, Yuttana Sudjaroen

Email(s): yuttana.su@ssru.ac.th

DOI: 10.52711/0974-360X.2024.00912   

Address: Kanittada Thongkao1, Pimporn Thongmuang2, Robert W. Owen3,4, Yuttana Sudjaroen1*
1Faculty of Science and Technology, Suan Sunandha Rajabhat University, Dusit, Bangkok 10300, Thailand.
2College of Allied Health Sciences, Suan Sunandha Rajabhat University, Muang, Samut Songkhram 75000, Thailand.
3Department of Organic and Inorganic Chemistry, Federal University of Ceara (UFC), Fortaleza, 60021-970 CE, Brazil.
4Biochemistry and Biomarkers Unit, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
*Corresponding Author

Published In:   Volume - 17,      Issue - 12,     Year - 2024


ABSTRACT:
Suaeda maritima root is acknowledged in Thai traditional medicine as prevention of hair loss and maintaining of hair colour. Nevertheless, there is a lack of scientific finding that has elucidating its possible applications in the realms of hair treatment. Our objectives of this study were to screen the active components contained in root extract; to assess its in vitro biological properties for prevention of hair loss and hair care. Total phenolic content (TPC), total flavonoid content (TFC), total tannin content (TTC) and total saponins (TSC) contained in Suaeda maritima root extract (SMRE) were 13.26±0.21 mg GAE/g, 67.41±0.27 mg QE/g, 92.34±2.56 mg TE/g and 364.67±2.97 mg TS/g, respectively. SMRE was strongly inhibited the albumin degradation (IC50 = 0.81±0.03 mg/ml) and the NO releasing from LPS-induced macrophage at 0.1 mg/ml (20.5±2.8%). However, SMRE was lack of anti-fungal activity against C. albicans and M. furfur when used of Kirby-Bauer method. SMRE (100 ?g/ml) and dutasteride (10 ?g/ml) were inhibited 19.71±0.48 and 51.91±3.35% of DNA intensity of 5a-reductase, respectively and implied less cytotoxicity. In conclusion, the use of S. maritima root as ingredient of hair cleansing and hair care products was considered by high content of saponins, antioxidant content and activity, and hair growth promotion.


Cite this article:
Kanittada Thongkao, Pimporn Thongmuang, Robert W. Owen, Yuttana Sudjaroen. Anti-hair loss and hair care properties from tropical halophyte, seablite (Suaeda maritima) root extract. Research Journal Pharmacy and Technology. 2024;17(12):6008-4. doi: 10.52711/0974-360X.2024.00912

Cite(Electronic):
Kanittada Thongkao, Pimporn Thongmuang, Robert W. Owen, Yuttana Sudjaroen. Anti-hair loss and hair care properties from tropical halophyte, seablite (Suaeda maritima) root extract. Research Journal Pharmacy and Technology. 2024;17(12):6008-4. doi: 10.52711/0974-360X.2024.00912   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-12-49


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