Author(s):
Kanittada Thongkao, Pimporn Thongmuang, Robert W. Owen, Yuttana Sudjaroen
Email(s):
yuttana.su@ssru.ac.th
DOI:
10.52711/0974-360X.2024.00912 
Address:
Kanittada Thongkao1, Pimporn Thongmuang2, Robert W. Owen3,4, Yuttana Sudjaroen1*
1Faculty of Science and Technology, Suan Sunandha Rajabhat University, Dusit, Bangkok 10300, Thailand.
2College of Allied Health Sciences, Suan Sunandha Rajabhat University, Muang, Samut Songkhram 75000, Thailand.
3Department of Organic and Inorganic Chemistry, Federal University of Ceara (UFC), Fortaleza, 60021-970 CE, Brazil.
4Biochemistry and Biomarkers Unit, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
*Corresponding Author
Published In:
Volume - 17,
Issue - 12,
Year - 2024
ABSTRACT:
Suaeda maritima root is acknowledged in Thai traditional medicine as prevention of hair loss and maintaining of hair colour. Nevertheless, there is a lack of scientific finding that has elucidating its possible applications in the realms of hair treatment. Our objectives of this study were to screen the active components contained in root extract; to assess its in vitro biological properties for prevention of hair loss and hair care. Total phenolic content (TPC), total flavonoid content (TFC), total tannin content (TTC) and total saponins (TSC) contained in Suaeda maritima root extract (SMRE) were 13.26±0.21 mg GAE/g, 67.41±0.27 mg QE/g, 92.34±2.56 mg TE/g and 364.67±2.97 mg TS/g, respectively. SMRE was strongly inhibited the albumin degradation (IC50 = 0.81±0.03 mg/ml) and the NO releasing from LPS-induced macrophage at 0.1 mg/ml (20.5±2.8%). However, SMRE was lack of anti-fungal activity against C. albicans and M. furfur when used of Kirby-Bauer method. SMRE (100 ?g/ml) and dutasteride (10 ?g/ml) were inhibited 19.71±0.48 and 51.91±3.35% of DNA intensity of 5a-reductase, respectively and implied less cytotoxicity. In conclusion, the use of S. maritima root as ingredient of hair cleansing and hair care products was considered by high content of saponins, antioxidant content and activity, and hair growth promotion.
Cite this article:
Kanittada Thongkao, Pimporn Thongmuang, Robert W. Owen, Yuttana Sudjaroen. Anti-hair loss and hair care properties from tropical halophyte, seablite (Suaeda maritima) root extract. Research Journal Pharmacy and Technology. 2024;17(12):6008-4. doi: 10.52711/0974-360X.2024.00912
Cite(Electronic):
Kanittada Thongkao, Pimporn Thongmuang, Robert W. Owen, Yuttana Sudjaroen. Anti-hair loss and hair care properties from tropical halophyte, seablite (Suaeda maritima) root extract. Research Journal Pharmacy and Technology. 2024;17(12):6008-4. doi: 10.52711/0974-360X.2024.00912 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-12-49
REFERENCES:
1. Guzman E, Lucia A. Essential oils and their individual components in cosmetic products. Cosmetics. 2021; 8(4): 114. doi.org/10.3390/cosmetics8040114
2. Giustra M, Cerri F, Anadol Y, Salvioni L, Antonelli Abella T, Prosperi D, et al. Eco-luxury: Making sustainable drugs and cosmetics with Prosopis cineraria natural extracts. Frontiers in Sustainability. 2022; 3: 1047218. doi.org/10.3389/frsus.2022.1047218
3. Gayatri MP, Maithilee R, Prachi SC, Maitrey SA, Sanchit AP, Tejas SP, et al. An Overview on Indian herbs in hair care therapy. Research Journal of Pharmacognosy and Phytochemistry. 2023; 15(2): 161-6. doi.org/10.52711/0975-4385.2023.00025
4. Ayyappadasan G, Rubavathi S, Kanimozli S. Formulation and evaluation of polyherbal-spirulina based conditioning and antioxidant shampoo. Research Journal of Pharmacy and Technology. 2023; 16(5): 2317-1. doi.org/ 10.52711/0974-360X.2023.00381
5. Gite SS, Jadhav AJ, Zalte AG, Saudagar RB. A Review on oils used in herbal cosmetics. Research Journal of Topical and Cosmetic Sciences. 2013; 4(1): 61-4.
6. Sonawane Sneha K, Shinde Prajakta P, Shelke Suvarna J. Shampoos: hair care cosmetics. Research Journal of Topical and Cosmetic Sciences. 2021; 12(2): 102-6. doi.org/ 10.52711/2321-5844.2021.00014
7. Varsha ST, Sagar SS, Megha AS, Asad AS, Sakshi PS, Jahanare RS. Formulation and evaluation of polyherbal shampoo containing different herbal extract. Research Journal of Topical and Cosmetic Sciences. 2022; 13(2): 87-1. doi.org/ 10.52711/2321-5844.2022.00014
8. Jitendra TB, Rushikesh SM. A Review on oils used in herbal cosmetics. Research Journal of Topical and Cosmetic Sciences. 2022; 13(2): 101-4. doi.org/ 10.52711/2321-5844.2022.00017
9. Harshada IP, Ketan M, Sayali P. Marketing Research - An examination of consumer preferences for shampoo brands. Research Journal of Topical and Cosmetic Sciences. 2023; 14(1): 01-6. doi.org/ 10.52711/2321-5844.2023.00001
10. Poonam CR, Anjali MW. A Review on-types and treatment of alopecia. Asian Journal of Pharmaceutical Research. 2023; 13(2): 123-8. doi.org/ 10.52711/2231-5691.2023.00025
11. Aljuffali IA, Sung CT, Shen FM, Huang CT, Fang JY. Squarticles as a Lipid Nanocarrier for Delivering Diphencyprone and Minoxidil to Hair Follicles and Human Dermal Papilla Cells. The AAPS Journal. 2013; 16(1): 140-50. doi.org/10.1208/s12248-013-9550-y
12. Bertolini M, McElwee K, Gilhar A, Bulfone‐Paus S, Paus R. Hair follicle immune privilege and its collapse in alopecia areata. Experimental Dermatology. 2020; 29(8): 703–25. doi.org/10.1111/exd.14155
13. Shen YL, Li XQ, Pan RR, Yue W, Zhang LJ, Zhang H. Medicinal plants for the treatment of hair loss and the suggested Mechanisms. Current Pharmaceutical Design. 2018; 24(26): 3090–100. doi.org/10.2174/1381612824666180911114810
14. Kubo C, Ogawa M, Uehara N, Katakura Y. Fisetin Promotes hair growth by augmenting TERT expression. Frontiers in Cell and developmental Biology. 2020; 8: 566617. doi.org/10.3389/fcell.2020.566617
15. Das D, Sarangi AK, Mohapatra RK, Parhi PK, Mahal A, Sahu R, et al. Aqueous extract of Shikakai; a green solvent for deoximation reaction: Mechanistic approach from experimental to theoretical. Journal of Molecular Liquids. 2020; 309: 113133. doi.org/10.1016/j.molliq.2020.113133
16. Vikrant A, Raneev T. Plant saponins –A recent update. Asian Journal of Research Chemistry. 2013; 6(9): 871-6.
17. Rani S. Management of Greying of Hairs (Sheeb) and Use of Hair Dyes (Khizaab) in Unani Medicine. TANG [HUMANITAS MEDICINE]. 2018; 8(2): 7.1-7.12. doi.org/10.5667/TANG.2018.0010
18. Hajimehdipoor H, Nikmanesh N, Mohammadi-Motamed S. Amla Oil, a pharmaceutical product based on traditional knowledge for hair loss treatment. Research Journal of Pharmacognosy. 2019; 6(1): 80373. doi.org/10.22127/rjp.2018.80373
19. Aswini KS, Faruk A, Sruti RM. A Comprehensive Review on medicinal plants for the remedy of hair loss. Research Journal of Pharmacy and Technology. 2023; 16(11): 5497-1. doi.org/ 10.52711/0974-360X.2023.00889
20. Pooja J, Parimal K. The Wonder of herbs to treat – alopecia. Asian Journal of Pharmacy and Technology. 2022; 12(2): 151-8. doi.org/ 10.52711/2231-5713.2022.00026
21. Dario MF, Pahl R, de Castro JR, de Lima FS, Kaneko TM, Pinto CASO, et al. Efficacy of Punica granatum L. hydroalcoholic extract on properties of dyed hair exposed to UVA radiation. Journal of Photochemistry and Photobiology B: Biology. 2013; 120: 142–7. doi.org/10.1016/j.jphotobiol.2012.12.011
22. Singleton VL, Orthofer R, Lamuela-Raventós RM. Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods in Enzymology. 1999; 299:152-78. doi.org/10.1016/s0076-6879(99)99017-1
23. Biju J, Sulaiman CT, Satheesh G, Reddy VRK. Total phenolics and flavonoids in selected medicinal plants from Kerala. International Journal of Pharmacy Pharmaceutical Science. 2014; 6: 406-8.
24. Association of Official Analytical Chemists (AOAC). Official methods of analysis of the Association of Official Analytical Chemists (18th ed.). AOAC, Washington. 2005.
25. Nickel J, Spanier LP, Botelho FT, Gularte MA, Helbig E. Effect of different types of processing on the total phenolic compound content, antioxidant capacity, and saponin content of Chenopodium quinoa Willd grains. Food Chemistry. 2016; 209: 139–43. doi.org/10.1016/j.foodchem.2016.04.031
26. Manosroi A, Kumguan K, Chankhampan C, Manosroi W, Manosroi J. Nanoscale Gelatinase A (MMP-2) Inhibition on Human Skin Fibroblasts of Longkong (Lansium domesticum Correa) Leaf Extracts for Anti-Aging. Journal of Nanoscience and Nanotechnology. 2012; 12(9): 7187–97. doi.org/10.1166/jnn.2012.6500
27. Aktas N, Genc Y, Gozcelioglu B, Konuklugil B, Harput US. Radical scavenging effect of different marine sponges from Mediterranean coasts. Records of Natural Products. 2013; 7(2): 96-104.
28. Yen GC, Duh PD. Scavenging Effect of Methanolic Extracts of peanut hulls on free-radical and active-oxygen species. Journal of Agricultural and Food Chemistry. 1994; 42(3): 629–32. doi.org/10.1021/jf00039a005
29. Chandra S, Chatterjee P, Dey P, Bhattacharya S. Evaluation of in vitro anti-inflammatory activity of coffee against the denaturation of protein. Asian Pacific Journal of Tropical Biomedicine. 2012; 2(1): S178–80. doi.org/10.1016/s2221-1691(12)60154-3
30. Torres-Rodríguez ML, García-Chávez E, Berhow M, de Mejia EG. Anti-inflammatory and anti-oxidant effect of Calea urticifolia lyophilized aqueous extract on lipopolysaccharide-stimulated RAW 264.7 macrophages. Journal of Ethnopharmacology. 2016; 188: 266–74. doi.org/10.1016/j.jep.2016.04.057
31. Bauer AW, Kirby WMM, Sherris JC, Turck M. Antibiotic susceptibility testing by a standardized single disk method. American Journal of Clinical Pathology. 1966; 45(4_ts): 493–6. doi.org/10.1093/ajcp/45.4_ts.493
32. Vichai V, Kirtikara K. Sulforhodamine B colorimetric assay for cytotoxicity screening. Nature Protocols. 2006; 1(3): 1112–6. doi.org/10.1038/nprot.2006.179
33. Ruksiriwanich W, Manosroi J, Abe M, Manosroi W, Manosroi A. 5α-Reductase type 1 inhibition of Oryza sativa bran extract prepared by supercritical carbon dioxide fluid. The Journal of Supercritical Fluids. 2011; 59: 61–71. doi.org/10.1016/j.supflu.2011.07.017
34. Manojkumar S, Thandeeswaran M, Thangavel SK, Arjunan A, Muthuselvam M, Kalaiarasi G, et al. Phytochemical Screening, In Silico Molecular Docking, ADME Properties, and In Vitro Antioxidant, Anticancer, and Antidiabetic Activity of Marine Halophyte Suaeda maritima (L.) Dumort. ACS Omega. 2024; 9(10): 11200-16. doi.org/10.1021/acsomega.3c05591
35. Patra J, Dhal N, Thatoi H. In vitro bioactivity and phytochemical screening of Suaeda maritima (Dumort): A mangrove associate from Bhitarkanika, India. Asian Pacific Journal of Tropical Medicine. 2011; 4(9): 727–34. doi.org/10.1016/s1995-7645(11)60182-x
36. Bandaranayake WM. Bioactivities, bioactive compounds and chemical constituents of mangrove plants. Wetlands Ecology and Management. 2002; 10(6): 421–52. doi.org/10.1023/a:1021397624349
37. Ravikumar S, Gnanadesigan M, Inbaneson JS, Kalaiarasi A. Hepatoprotective and antioxidant properties of Suaeda maritima (L.) Dumort ethanolic extract on concanavalin-A induced hepatotoxicity in rats. Indian Journal of Experimental Biology. 2011; 49: 455-60.
38. Um S, Lee J, Kim SJ, Cho KA, Kang KS, Kim SH. Xinghamide A, a New Cyclic Nonapeptide Found in Streptomyces xinghaiensis. Marine Drugs. 2023; 21(10): 509. doi.org/10.3390/md21100509
39. Kregiel D, Berlowska J, Witonska I, Antolak H, Proestos C, Babic M, et al. Saponin-Based, Biological-Active Surfactants from Plants. Application and Characterization of Surfactants. 2017: 68062. doi.org/10.5772/68062
40. Rathi S, D′Souza P. Shampoo and conditioners: What a dermatologist should know? Indian Journal of Dermatology. 2015; 60(3): 248. doi.org/10.4103/0019-5154.156355
41. Panda A, Kumar A, Mishra S, Mohapatra SS. Soapnut: A replacement of synthetic surfactant for cosmetic and biomedical applications. Sustainable Chemistry and Pharmacy. 2020; 17: 100297. doi.org/10.1016/j.scp.2020.100297
42. Fraga CG, Galleano M, Verstraeten SV, Oteiza PI. Basic biochemical mechanisms behind the health benefits of polyphenols. Molecular Aspects of Medicine. 2010; 31(6): 435–45. doi.org/10.1016/j.mam.2010.09.006
43. Schwartz J, Messenger A, Tosti A, Todd G, Hordinsky M, Hay R, et al. A Comprehensive Pathophysiology of Dandruff and Seborrheic Dermatitis – Towards a More Precise Definition of Scalp Health. Acta Dermato Venereologica. 2013; 93(2): 131–7. doi.org/10.2340/00015555-1382
44. Xu Z, Wang Z, Yuan C, Liu X, Yang F, Wang T, et al. Dandruff is associated with the conjoined interactions between host and microorganisms. Scientific Reports. 2016; 6(1). doi.org/10.1038/srep24877
45. Wolf R, Schönfelder G, Paul M, Blume-Peytavi U. Nitric oxide in the human hair follicle: constitutive and dihydrotestosterone-induced nitric oxide synthase expression and NO production in dermal papilla cells. Journal of Molecular Medicine. 2002; 81(2): 110–7. doi.org/10.1007/s00109-002-0402-y
46. Zgonc Škulj A, Poljšak N, Kočevar Glavač N, Kreft S. Herbal preparations for the treatment of hair loss. Archives of Dermatological Research. 2019; 312(6): 395–406. doi.org/10.1007/s00403-019-02003-x
47. Yang F, Song L, Wang H, Wang J, Xu Z, Xing N. Quercetin in prostate cancer: Chemotherapeutic and chemopreventive effects, mechanisms and clinical application potential (Review). Oncology Reports. 2015; 33(6): 2659–68. doi.org/10.3892/or.2015.3886
48. Rondanelli M, Perna S, Peroni G, Guido D. A bibliometric study of scientific literature in Scopus on botanicals for treatment of androgenetic alopecia. Journal of Cosmetic Dermatology. 2015; 15(2): 120–30. doi.org/10.1111/jocd.12198
49. Loing E, Lachance R, Ollier V, Hocquaux M. A new strategy to modulate alopecia using a combination of two specific and unique ingredients. Journal of Cosmetic Science. 2013; 64: 45–58.