Author(s): Parixit Prajapati, Pankaj Kapupara, Hitesh Vekariya

Email(s): parixitprajapati@gmail.com

DOI: 10.52711/0974-360X.2024.00867   

Address: Parixit Prajapati1*, Pankaj Kapupara2, Hitesh Vekariya2
1Research Scholar, Department of Pharmaceutical Chemistry, School of Pharmacy, RK University, Rajkot, Gujarat, India.
2Professor, School of Pharmacy, RK University, Rajkot, Gujarat, India.
*Corresponding Author

Published In:   Volume - 17,      Issue - 12,     Year - 2024


ABSTRACT:
Recently, Vildagliptin and Remogliflozin together have become a viable treatment choice for diabetes. The invention of HPTLC (High Performance Thin Layer Chromatography) approach for the concurrent measurement of Vildagliptin (VILG) and Remogliflozin (REMO) in both their pure API (Active Pharmaceutical Ingredient) forms and in a commercially accessible formulation is shown in the present work. The method is robust, selective, sensitive, and fast. Utilizing a solvent solution consisting of toluene: ethyl acetate: methanol and glacial acetic acid (2.0: 6.0: 0.5: 0.1, v/v/v/v), the separation was successfully accomplished on silica gel F254. The chromatographic bands were observed at a wavelength of 250nm in short-wave ultraviolet light. With retention factor Rf values of 0.36 and 0.71 for REMO and VILG, correspondingly, proposed method showed clearly delineated spots.


Cite this article:
Parixit Prajapati, Pankaj Kapupara, Hitesh Vekariya. Simultaneous Analysis of Remogliflozin Etabonate and Vildagliptin in Tablets by HPTLC: Method Development and Validation. Research Journal Pharmacy and Technology. 2024;17(12):5697-1. doi: 10.52711/0974-360X.2024.00867

Cite(Electronic):
Parixit Prajapati, Pankaj Kapupara, Hitesh Vekariya. Simultaneous Analysis of Remogliflozin Etabonate and Vildagliptin in Tablets by HPTLC: Method Development and Validation. Research Journal Pharmacy and Technology. 2024;17(12):5697-1. doi: 10.52711/0974-360X.2024.00867   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-12-4


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