Author(s):
Janani Manoharan, Parimala Shantha Kumari T, Punithavathi V.R, Mukesh Kumar Dharmalingam Jothinathan, Arulanandam Adaikalam, Devipriya Anbumani
Email(s):
jananimanoharan21@gmail.com
DOI:
10.52711/0974-360X.2024.00899 
Address:
Janani Manoharan1*, Parimala Shantha Kumari T2, Punithavathi V.R3, Mukesh Kumar Dharmalingam Jothinathan4, Arulanandam Adaikalam5, Devipriya Anbumani6
1Department of Biochemistry, Auxilium College (Autonomous), Gandhi Nagar, Vellore- 632 006, Tamil Nadu, India.
2Department of Zoology, Voorhees College, Vellore-632001, Tamil Nadu, India.
3Department of Biotechnology, M.M.E.S Women’s Arts and Science College, Melvisharam-632509, Tamil Nadu, India.
4Centre for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India.
5Department of Languages, School of Social Sciences and Languages, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
6Nano and Energy Bioscience Laboratory, Department of Biotechnology, Thiruvalluvar University, Serkkadu, Vellore-632 115, Tamil Nadu, India.
*Corresponding Author
Published In:
Volume - 17,
Issue - 12,
Year - 2024
ABSTRACT:
The applicability of medicinally imperative plants for well-being of human hold historical background. Products of natural origin are the pivotal source of medicament. Amid all, plant-rooted medicines are the exemplary natural source. The failure of allopathic medicines in terms of their aftereffect have tuned keen interest and practice of medicinal plants and their derivative products. The pharmacologically functional phytophenolics were amendable for the therapeutic attributes of medicinal plants. Acacia nilotica or A.nilotica (Babul/Kikar) an ayurvedic tree was used in this study. Applying soxhlation technique the aqueous bark extract from A.nilotica was pertained. GC-MS chromatogram elucidated 11 bioactive entities, connected with pharmacological traits that included 1,2,3-benzenetriol (Pyrogallol), estra-1,3,5(10)-trien-17ß-ol, ethanamine, nonadecane, n-octadecane and pentanoic acid. Furthermore, n-hexadecanoic acid, octanoic acid, 1,2-benzenedicarboxylic acid, benzeneacetic acid and eicosane were recognized in the extract. Pseudomonas aeruginosa (14.6 ± 0.21 mm) displayed greater antibacterial activity, followed by Bacillus cereus (14.4 ± 0.38 mm), Staphylococcus aureus (13.6 ± 0.33 mm), Klebsiella pneumoniae (12.9 ± 0.30 mm), Bacillus subtilis (12.6 ± 0.24 mm) and the least inhibitory zone was given by Escherichia coli (10.2 ± 0.52 mm) at 40 µg/mL. All the outcomes validated the antibacterial attributes of A.nilotica bark pertained aqueous extract.
Cite this article:
Janani Manoharan, Parimala Shantha Kumari T, Punithavathi V.R, Mukesh Kumar Dharmalingam Jothinathan, Arulanandam Adaikalam, Devipriya Anbumani. GC-MS Profiling and antibacterial activity of Acacia nilotica bark pertained aqueous extract. Research Journal Pharmacy and Technology. 2024;17(12):5931-6. doi: 10.52711/0974-360X.2024.00899
Cite(Electronic):
Janani Manoharan, Parimala Shantha Kumari T, Punithavathi V.R, Mukesh Kumar Dharmalingam Jothinathan, Arulanandam Adaikalam, Devipriya Anbumani. GC-MS Profiling and antibacterial activity of Acacia nilotica bark pertained aqueous extract. Research Journal Pharmacy and Technology. 2024;17(12):5931-6. doi: 10.52711/0974-360X.2024.00899 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-12-36
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