Author(s):
Raudas Abdul Khakim Nasser, Fadi Hajjar, Sergey Vladimirovich Goryainov, Alexander Vladimirovich Nikulin, Vasilii Alexandrovich Ivlev, Olga Georgievna Potanina, Vasilii Gennadievich Vasiliev, Anzhelika Valerievna Sheremeta, Svetlana Anatolyevna Kovaleva, Rimma Alexandrovna Abramovich, Gennady Alexandrovich Kalabin.
Email(s):
phfadyhajj@gmail.com
DOI:
10.52711/0974-360X.2024.00825 
Address:
Raudas Abdul Khakim Nasser 1, Fadi Hajjar1*, Sergey Vladimirovich Goryainov1, Alexander Vladimirovich Nikulin3, Vasilii Alexandrovich Ivlev1, Olga Georgievna Potanina2, Vasilii Gennadievich Vasiliev1, Anzhelika Valerievna Sheremeta1, Svetlana Anatolyevna Kovaleva1, Rimma Alexandrovna Abramovich2, Gennady Alexandrovich Kalabin1
1Рeoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, Moscow, 117198, Russian Federation.
2Lomonosov Moscow State University, 1 Leninskie Gory, Moscow, 119991, Russian Federation.
3MIREA – Russian Technological University (M.V. Lomonosov Institute of Fine Chemical Technologies), 86 Vernadsky Avenue, 119571, Central Federal Destrict, Moscow, Russian Federation.
*Corresponding Author
Published In:
Volume - 17,
Issue - 11,
Year - 2024
ABSTRACT:
The lipid complex of the aboveground part of Portulaca oleracea L., which constitutes around 2.0% of the plant material, was thoroughly analyzed using a combination of advanced techniques including GC-MS, GC-FID and 1H NMR spectroscopy. The study delved into the qualitative and quantitative composition of various components such as fatty acids, tocopherols, sterols, and triterpene alcohols present in the lipid complex. The primary structural element identified in the complex is wax, with prominent percentages of a-linolenic (23.5%), linoleic (24.7%), and palmitic (25.3%) acids. The tocopherol content in the lipid complex was found to be approximately 0.02%, with ß- and ?-tocopherols making up to 40% of the fraction. Additionally, d-tocopherol and a-tocopherol were present in roughly equal amounts, each constituting about 30% of the tocopherol content. The lipid complex also contains sterols and triterpene alcohols, with a total content of 691.3 mg/100g (0.7%) in the fraction. The main components of this fraction included ß-sitosterol (44.0%), ?7-sitosterol (13.2%), and cycloartenol (7.7%). These detailed analyses highlight the potential of Portulaca oleracea L. as a promising raw material for the extraction of a lipid complex, offering opportunities for further pharmacotherapeutic research and applications.
Cite this article:
Raudas Abdul Khakim Nasser, Fadi Hajjar, Sergey Vladimirovich Goryainov, Alexander Vladimirovich Nikulin, Vasilii Alexandrovich Ivlev, Olga Georgievna Potanina, Vasilii Gennadievich Vasiliev, Anzhelika Valerievna Sheremeta, Svetlana Anatolyevna Kovaleva, Rimma Alexandrovna Abramovich, Gennady Alexandrovich Kalabin. Study of Lipid Complex Composition of Portulaca oleracea L. Herbs. Research Journal of Pharmacy and Technology. 2024; 17(11):5399-4. doi: 10.52711/0974-360X.2024.00825
Cite(Electronic):
Raudas Abdul Khakim Nasser, Fadi Hajjar, Sergey Vladimirovich Goryainov, Alexander Vladimirovich Nikulin, Vasilii Alexandrovich Ivlev, Olga Georgievna Potanina, Vasilii Gennadievich Vasiliev, Anzhelika Valerievna Sheremeta, Svetlana Anatolyevna Kovaleva, Rimma Alexandrovna Abramovich, Gennady Alexandrovich Kalabin. Study of Lipid Complex Composition of Portulaca oleracea L. Herbs. Research Journal of Pharmacy and Technology. 2024; 17(11):5399-4. doi: 10.52711/0974-360X.2024.00825 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-11-33
REFERENCES:
1. Sadhana Jaiswal, Deepali Rajwade A Review on Portulaca oleracea (Nonia bhaji): A wonderful weed of Chhattisgarh Research J. Pharm. and Tech. 2017; 10(7): 2415-2420.
2. Hayat M. Mukhtar, Prince Ahad Mir, Babar Ali, Subash Yadav Preliminary Phytochemical Standardisation of Portulaca oleracea Linn. Research J. Pharm. and Tech. 2012; Mar. 5(3): 411-414.
3. Komarov VL, Vasil'chenko IT, Gorshkova SG, Il'in MM, Kuzeneva OI, Knorring OE, Murav'eva OA, Tolmachev AI, Shishkin BK, Shteynberg EI. 1936. URSS (Flora Unionis Rerumpublicarum Sovieticarum Socialisticarum). Moscow: Academy of Sciences of the USSR Publisher.
5. Trupti P. Durgawale, Chitra C. Khanwelkar, Pratik P. Durgawale Phytochemical Screening using GC-MS and study of Anti-Oxidant Activity of two species of Portulaca Research J. Pharm. and Tech. 2018; 11(12): 5534-5540
6. Boschelle O, Sblattero S, Da Porto C, Frega N, Lercker G. Lipid composition of Portulaca oleracea. Riv. Ital. Sostanze Grasse, 1991; 68(6): 287.
7. Uddin MK, Juraimi AS, Ali ME, Ismail MR. Evaluation of antioxidant properties and mineral composition of Purslane (Portulaca oleracea L.) at different growth stages. Int J Mol Sci, 2012; 13(8): 13.
8. Agha-Hosseini F, Borhan-Mojabi K, Monsef-Esfahani HR, Mirzaii-Dizgaah I, Etemad-Moghadam S, Karagah A. Efficacy of purslane in the treatment of oral lichen planus. Phytother Res, 2010; 24(2): 24.
9. Omara-Alwala TR, Mebrhatu T, Prior DE, Ezekwe MO. Ω-three fatty acids in purslane (Portulaca oleracea) tissues. J. Am. Oil Chem. Soc, 1991; 63(3): 3-198.
10. Simopoulos AP, Norman HA, Gillaspy JE, Duke JA. Common purslane: a source of ω 3-fatty acids and antioxidants. J. Am. Coll. Nutr, 1992; 11(4): 374.
11. Siriamornpun S, Suttajit M. Microchemical Components and Antioxidant Activity of Different Morphological Parts of Thai Wild Purslane (Portulaca oleracea). Weed Science, 2010; 58(3): 182–188.
12. USDA: Agricultural research service. National Nutrient Database for Standard Reference. SR Legacy, purslane Raw, 2019; 169274.
13. Goryainov SV, Khromov AV, Bakureza G, Esparsa C, Ivlev VA, Vorobyеv AN, Abramovich RA, Potanina OG, Novikov OO. Results of a comparative study of Nigella Sativa L. Seeds oils composition. Pharmacy & Pharmacology. 2020; 8(1): 29-39.
14. A. Ismail and Y. Alahmad. Determination of ethanol and n-hexane residues in bulk rosuvastatin and atorvastatin and their dosage forms using HS-GC-MS developed method: Research J. Pharm. and Tech 2018; 11(11): 4829-4836. doi: 10.5958/0974- 360X.2018.00878.8.
15. S. Srinivasa Rao, A. Vijayalakshmi. Analytical Method Development and Validation of Glipizide to Determine Residual solvents by head Space-Gas Chromatography. Research Journal of Pharmacy and Technology. 2021; 14(5): 2440-4. doi: 10.52711/0974-360X.2021.00429.
16. Fadi Hajjar, S. V. Goriainov, O. G. Potanina Quantitative determination content for the Residual Organic Solvents in a combined drug based on Jacob's Ladder herbs, motherwort herbs and hawthorn fruit by GC- FID. Research J. Pharm. and Tech. 2022; 15(8):3669-3673
17. S. Alahmad and M. Almardini. Validated HS-GC-FID Method for Determination of Residual Ethanol in Solid Dosage Form. Research J. Pharm. and Tech. 2014; 7(2): 184-187.
18. JY Nehete and VV Shewale. Gas Chromatographic Ethanol Determination in Bhunimbadi Kwath. Research J. Pharm. and Tech. 2009; 2 (4): 876-877.