Author(s):
Sudhish Rai, Ashish Sarkar
Email(s):
sudhishrai7337@gmail.com
DOI:
10.52711/0974-360X.2024.00778
Address:
Sudhish Rai1*, Ashish Sarkar2
1Research Scholar, School of Pharmacy, YBN University, Ranchi, Jharkhand.
2School of Pharmacy, YBN University, Ranchi, Jharkhand.
*Corresponding Author
Published In:
Volume - 17,
Issue - 10,
Year - 2024
ABSTRACT:
Plants are nature's amazing gift given to society packed with essential nutrients, Phyto-vitamins, minerals, and fibers, there are many essential uses of plants, they are the absolute feast in our daily life and considered to be a unique profile for fighting against different kinds of diseases. The plant Laxmitaru (Simarouba glacuoa) is a fruit-bearing deciduous shrub that belongs to the Family – Simaroubeaceae native from the areas of the Himalayas in Northern India, cultivated all over the Mediterranean region from ancient times. The method development and quantitative analysis of quassionoids in laxmitaru leaves are developed using the solvent system Toluene: Ethyl acetate: Formic acid in the ratio (7: 2: 1 v/v/v) and the method is successfully developed. The punicalagin is quantified at 257 nm, Rf value =1.8. The content found in the various samples in M1 is 440.8µg, in M2 is 472.4 µg , in M3 is 458.8 µg and for in-house is 456.8 µg of quassionoids from 1 g of each sample. The developed method was validated according to ICH guidelines Q2R2.
Cite this article:
Sudhish Rai, Ashish Sarkar. Quantification of Quassionoids in Laxmi taru (Simarouba glacuoa) leaves from High Performance Thin layer Chromatography (HPTLC). Research Journal of Pharmacy and Technology. 2024; 17(10):5062-4. doi: 10.52711/0974-360X.2024.00778
Cite(Electronic):
Sudhish Rai, Ashish Sarkar. Quantification of Quassionoids in Laxmi taru (Simarouba glacuoa) leaves from High Performance Thin layer Chromatography (HPTLC). Research Journal of Pharmacy and Technology. 2024; 17(10):5062-4. doi: 10.52711/0974-360X.2024.00778 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-10-63
REFERENCES:
1. Singh LR, Garg S. Medicinal Potential of Laxmi Taru (Simarouba Glauca DC). Dev Sanskriti Interdisciplinary International Journal. 2021; Jul 31;18:40-5.
2. Fernandes J, Vaz T, Anvekar TS. Antimicrobial and antioxidant therapy with bioactive plant molecules on Fe 3 O 4 phytohybrid nanoplatforms. Future Journal of Pharmaceutical Sciences. 2021; Dec; 7: 1-1.
3. Puthani P, Jeeragal R, Patil AT, Chanagond M. Influence of Simarouba Glauca (Laxmi taru) biodiesel on engine performance and emissions of conventional compression ignition engine. InIOP Conference Series: Earth and Environmental Science. 2022; Jul 1 1042 (1): 12004
4. Jose A, Kannan E, Kumar PR, Madhunapantula SV. Therapeutic potential of phytochemicals isolated from Simarouba glauca for inhibiting cancers: A review. Systematic Reviews in Pharmacy. 2019; 10(1): 73-80.
5. https://www.ich.org/page/quality-guidelines