Author(s): Ira Arundina, Aqsa Sjuhada Oki, Theresia Indah Budhy, Azzahra Salsabila Adira Moelyanto, Sheryn Marcha Ramaniasari, Ekarista Lussiana Ferdinandus, Ahmad Afif Dzulfikar, Irfan Prasetyo, Arvia Diva Firstiana, Tytania Rahmaputry, Arya Pradana

Email(s): arundinaira@gmail.com

DOI: 10.52711/0974-360X.2024.00070   

Address: Ira Arundina1*, Aqsa Sjuhada Oki1, Theresia Indah Budhy2, Azzahra Salsabila Adira Moelyanto3, Sheryn Marcha Ramaniasari3, Ekarista Lussiana Ferdinandus4, Ahmad Afif Dzulfikar4, Irfan Prasetyo4, Arvia Diva Firstiana4, Tytania Rahmaputry5, Arya Pradana5
1Department of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
2Department of Oral Pathology and Maxillofacial, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
3Master Student of Dental Health Science, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
4Student of Conservative Dentistry Specialist of Dental Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
5Undergraduate Student, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
*Corresponding Author

Published In:   Volume - 17,      Issue - 1,     Year - 2024


ABSTRACT:
SARS-CoV-2 causes COVID-19 (Corona Virus Infection Disease-19), an infectious disease (Severe Acute Respiratory Syndrome Corona Virus-2)virus which was first confirmed on December 2, Wuhan, China, in 2019 and very quickly world-wide. World Health Organization (WHO) declared it on March 11th, 2020,fever, cough, and breathing difficulties are all common symptoms. The gold standard for diagnosing SARS-CoV-2 infection is the real-time reverse transcription polymerase chain reaction (rRT-PCR)by detecting viral RNA using nasopharyngeal swabs and other respiratory specimens. However, this process necessitates the use of specialist medical staff, centralized laboratory facilities, and a lengthy period of time for results to be obtained. Besides that, the possibility of virus transmission is not negligiblefor procedure's operator. Due to this reason, several investigations have shown that other bodily fluids, like as saliva, could be used to identify SARS-CoV-2. Saliva is used as a diagnostic sample has many advantages: it is easy to collect samples by the patient themselves with a fairly comfortable procedure, does not require health personnel with special expertise to manage it, and reduces the risk of transmitting the virus to the operator. Currently, there are several alternative tests for SARS-CoV-2 which have simpler and more efficient procedures, such as antigen based rapid diagnostic tests, antibody based rapid diagnostics, and RT LAMP tests. This examination is suitable for screening and mass examination, but cannot be used as a primary diagnostic tool because the sensitivity and specificity are not as high as rRT-PCR.


Cite this article:
Ira Arundina, Aqsa Sjuhada Oki, Theresia Indah Budhy, Azzahra Salsabila Adira Moelyanto, Sheryn Marcha Ramaniasari, Ekarista Lussiana Ferdinandus, Ahmad Afif Dzulfikar, Irfan Prasetyo, Arvia Diva Firstiana, Tytania Rahmaputry, Arya Pradana. The Role of Saliva in Examining for SARS-CoV-2. Research Journal of Pharmacy and Technology. 2024; 17(1):443-1. doi: 10.52711/0974-360X.2024.00070

Cite(Electronic):
Ira Arundina, Aqsa Sjuhada Oki, Theresia Indah Budhy, Azzahra Salsabila Adira Moelyanto, Sheryn Marcha Ramaniasari, Ekarista Lussiana Ferdinandus, Ahmad Afif Dzulfikar, Irfan Prasetyo, Arvia Diva Firstiana, Tytania Rahmaputry, Arya Pradana. The Role of Saliva in Examining for SARS-CoV-2. Research Journal of Pharmacy and Technology. 2024; 17(1):443-1. doi: 10.52711/0974-360X.2024.00070   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-1-70


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