Author(s):
Farheen Naaz, Arti Majumdar, Neelesh Malviya, Priya Mourya, Manisha Dhere
Email(s):
dheremanisha25@gmail.com
DOI:
10.52711/0974-360X.2024.00058 
Address:
Farheen Naaz1*, Arti Majumdar2, Neelesh Malviya1, Priya Mourya1, Manisha Dhere1
1Smriti College of Pharmaceutical Education, Indore.
2IPS Academy, College of Pharmacy, Indore.
*Corresponding Author
Published In:
Volume - 17,
Issue - 1,
Year - 2024
ABSTRACT:
The present research was aimed to formulate a soft and easy to handle transdermal patch consisting simple and cost effective monolithic polymeric film as an attempt to deliver Febuxostat transdermallyand overcome problems associated with its poor bioavailability and hepatic first pass metabolism. Transdermal patches of Febuxostat were prepared by solvent casting method. Prepared formulations were evaluated for various parameters tensile strength, thickness, folding endurance, % moisture content, % moisture uptake, % drug content, % elongation, In vitro drug release. Based on the evaluation of transdermal patches, concluded that the concept of transdermal drug delivery is a novel, nontoxic as well cost-effective technique for enhancing the aqueous solubility and bioavailability of the drug. It can be concluded that transdermal drug delivery works very simple in which drug is applied inside the patch and it is worn on skin for long period of time. By this constant concentration of drug remain in blood for long time. Thus, overcome the adverse effects caused by oral route.
Cite this article:
Farheen Naaz, Arti Majumdar, Neelesh Malviya, Priya Mourya, Manisha Dhere. Formulation and Evaluation of Febuxostat Transdermal Patch for Management of Gout. Research Journal of Pharmacy and Technology. 2024; 17(1):373-8. doi: 10.52711/0974-360X.2024.00058
Cite(Electronic):
Farheen Naaz, Arti Majumdar, Neelesh Malviya, Priya Mourya, Manisha Dhere. Formulation and Evaluation of Febuxostat Transdermal Patch for Management of Gout. Research Journal of Pharmacy and Technology. 2024; 17(1):373-8. doi: 10.52711/0974-360X.2024.00058 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-1-58
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