Author(s): Sonal Nalkar, Shubhangi Sutar, Mayuresh Redkar, Priyanka More, Pooja Swami

Email(s): mayuresh.redkar253@gmail.com

DOI: 10.52711/0974-360X.2024.00055   

Address: Sonal Nalkar1,2, Shubhangi Sutar2, Mayuresh Redkar*3, Priyanka More4, Pooja Swami4
1Angarsiddha Shikshan Prasarak Manadal’s College of Pharmacy, Sangulwadi, Sindhudurg, 416810, (MS) India.
2Department of Quality Assurance, Ashokrao Mane College of Pharmacy, Peth-Vadgaon, Kolhapur 416001, (MS) India.
3Department of Pharmaceutics, Yashwantrao Bhonsale College of Pharmacy, Sawantwadi 416510, (MS) India.
4Angarsiddha Shikshan Prasarak Manadal’s College of D. Pharmacy, Sangulwadi, Sindhudurg, 416810, (MS) India.
*Corresponding Author

Published In:   Volume - 17,      Issue - 1,     Year - 2024


ABSTRACT:
A simple, precise, accurate, sensitive cheap and selective RP-HPLC method has been developed of salmeterol in bulk and pharmaceutical formulation. The method was carried out on an Inertsil ODS C18 (250 x 4.6mm, packed with 5µ). The maximum absorbance was found to be at 203nm. The Salmeterol xinafoate followed linearity in the concentration range 20 to 70ppm and correlation coefficient was found to be 0.999. Injection volume was selected to be 20µl and the flow rate was fixed at 1.0ml/min. Mobile phase selected with the ratio of methanol and water (60:40 v/v). Run time was selected to be 8min. Retention team was found to be 3.521. The LOD and LOQ were found to be 0.00471 and 0.01429.


Cite this article:
Sonal Nalkar, Shubhangi Sutar, Mayuresh Redkar, Priyanka More, Pooja Swami. User Friendly Analytical Method Development and Validation of Salmeterol Xinafoate an Antiasthmatic Drug in Bulk and Formulated Product. Research Journal of Pharmacy and Technology. 2024; 17(1):358-2. doi: 10.52711/0974-360X.2024.00055

Cite(Electronic):
Sonal Nalkar, Shubhangi Sutar, Mayuresh Redkar, Priyanka More, Pooja Swami. User Friendly Analytical Method Development and Validation of Salmeterol Xinafoate an Antiasthmatic Drug in Bulk and Formulated Product. Research Journal of Pharmacy and Technology. 2024; 17(1):358-2. doi: 10.52711/0974-360X.2024.00055   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-1-55


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