Author(s): Ida Bagus Narmada, Muhammad Fulan Ardhani, Sonya Liani Ramadhani, Inggit Dwi Virgianti, Putri Pramita Larasati, Ervina Restiwulan Winoto, Alexander Patera Nugraha, Tengku Natasha Eleena binti Tengku Ahmad Noor

Email(s): ida-b-n@fkg.unair.ac.id

DOI: 10.52711/0974-360X.2024.00005   

Address: Ida Bagus Narmada1,2*, Muhammad Fulan Ardhani1, Sonya Liani Ramadhani1, Inggit Dwi Virgianti1, Putri Pramita Larasati1, Ervina Restiwulan Winoto1,2, Alexander Patera Nugraha1,2, Tengku Natasha Eleena binti Tengku Ahmad Noor3,4
1Department of Orthodontic, Faculty of Dental Medicine - Universitas Airlangga, Surabaya.
2Dental Regenerative Research Group, Faculty of Dental Medicine, Airlangga University, Surabaya, Indonesia.
3Military Dental Officer of Royal Medical and Dental Corps, Malaysian Armed Forces.
4Membership of Faculty of Dental Surgery, Royal Collage of Surgeon, Edinburgh University, United Kingdom.
*Corresponding Author

Published In:   Volume - 17,      Issue - 1,     Year - 2024


ABSTRACT:
Dental and oral health is an essential factor that must be considered because it affects general body health. Streptococcus mutans is known to be a cause of dental plaque formation. Dental plaque is a biofilm formed by microorganisms from solid substrate bonds exopolymer matrix. Fixed orthodontic treatment in its use impacts changes in the environment and composition of the oral flora, as well as increases the amount of plaque accumulation that causes damage to hard tissue and periodontal tissue. The aim of this study is to investigate the minimum concentration of compounds in Hibiscus Sabdariffa L. extract in inhibiting metabolic activity and killing S. mutans in vitro. Methods: This study was an in vitro, the experimental study with post-test only control group design. First, H. Sabdariffa L. flower extraction was carried out with the help of distilled water, and then serial dilution was carried out to obtain various concentrations of H. Sabdariffa L. flower extract. Several S. mutans cultures were then exposed to various concentrations of H. Sabdariffa L. flower, and then a colony count was performed in each culture to identify Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC). It was found that S. mutans had 0% growth at a concentration between 25% and 100%, and S. mutans had a growth of 7.1% / 92.9% growth inhibition of S. mutans at a concentration of 12.5%. MBC of roselle flower extract against S. mutans is 25% and MIC of roselle flower extract against S. mutans is 12.5%.


Cite this article:
Ida Bagus Narmada, Muhammad Fulan Ardhani, Sonya Liani Ramadhani, Inggit Dwi Virgianti, Putri Pramita Larasati, Ervina Restiwulan Winoto, Alexander Patera Nugraha, Tengku Natasha Eleena binti Tengku Ahmad Noor. Hibiscus sabdariffa L. Flower Distilled Water Extract Antibacterial Activity towards Streptococcus mutans: An in vitro Study. Research Journal of Pharmacy and Technology. 2024; 17(1):25-0. doi: 10.52711/0974-360X.2024.00005

Cite(Electronic):
Ida Bagus Narmada, Muhammad Fulan Ardhani, Sonya Liani Ramadhani, Inggit Dwi Virgianti, Putri Pramita Larasati, Ervina Restiwulan Winoto, Alexander Patera Nugraha, Tengku Natasha Eleena binti Tengku Ahmad Noor. Hibiscus sabdariffa L. Flower Distilled Water Extract Antibacterial Activity towards Streptococcus mutans: An in vitro Study. Research Journal of Pharmacy and Technology. 2024; 17(1):25-0. doi: 10.52711/0974-360X.2024.00005   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-1-5


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