Author(s): Santosh Kumar, Shikhar Verma, Pritt Verma, Anant Kumar Shrivastav

Email(s): hygia.santoshkumar@gmail.com

DOI: 10.52711/0974-360X.2024.00037   

Address: Santosh Kumar1*, Shikhar Verma2, Pritt Verma3, Anant Kumar Shrivastav1
1Hygia Institute of Pharmaceutical Education and Research, Ghaila Road, Balrampur, Lucknow 226020, Uttar Pradesh, India.
2Maharishi School of Pharmaceutical Sciences, Maharishi University of Information Technology (MUIT), IIM Road Near Maharishi Vidya Mandir, Indrapuri Colony, Diguria, Aziz Nagar, Lucknow, Uttar Pradesh 226013, India.
3Goel Institute of Pharmacy and Sciences, Lucknow, Faizabad Road, Near Indira Canal, Lucknow, Uttar Pradesh 226028, India.
*Corresponding Author

Published In:   Volume - 17,      Issue - 1,     Year - 2024


ABSTRACT:
Phytomedicines are now an important area of better treatment and high prospects in many countries these medicinal herbs are found in tropical and subtropical areas and it is an erect, branched herb usually 2 to 3 m in height. The members of this species are annual and perennial. The leaves of the plant are alternate, paripinnate compound and the petiole possesses a dark purple-brown ovoid gland near the stem junction. Senna occidentalis (L.) also known as “Kasondi or coffee senna” is a herbaceous medicinal weed with orange-yellow to yellow flowers belonging to the family “Fabaceae (Leguminosae)” Senna occidentalis (L.). The present work was designed to investigate the presence of quercetin and gallic acid in the n-hexane and hydro-alcoholic extract of S. occidantalis through HPTLC. The result presented through chromatograms and peak tables reveals the presence of quercetin in the sample extracted with n-hexane and hydro-alcohol while gallic acid was not detected in n-hexane and hydro-alcohol extracted samples.


Cite this article:
Santosh Kumar, Shikhar Verma, Pritt Verma, Anant Kumar Shrivastav. HPTLC Analysis of Senna occidentalis (L.) in the Methanolic extract of the leaf. Research Journal of Pharmacy and Technology. 2024; 17(1):236-0. doi: 10.52711/0974-360X.2024.00037

Cite(Electronic):
Santosh Kumar, Shikhar Verma, Pritt Verma, Anant Kumar Shrivastav. HPTLC Analysis of Senna occidentalis (L.) in the Methanolic extract of the leaf. Research Journal of Pharmacy and Technology. 2024; 17(1):236-0. doi: 10.52711/0974-360X.2024.00037   Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-1-37


REFERENCES:
1.    K. Usha, G. Kasturi Mary, and P. Hemalatha. Hepatoprotective effect of hygrophila spinosa and Cassia occidentalism on carbon Tetrachloride induced liver damage in experimental rats. Indian Journal of Clinical Biochemistry. 2007; 22(2):  132–135.
2.    L. Verma, A. Khatri, B. Kaushik, U. Patil, and R. Pawar. Antidiabetic activity of Cassia occidentalis (Linn) in normal and alloxan-induced diabetic rats.  Indian Journal of Pharmacology. 2010; 42(4): 224–228.
3.    Kunle OF, Egharevba HO. Preliminary studies on Vernonia ambigua: Phytochemistry and Antimicrobial Screening of the Whole Plant. Ethnobot Leaf. 2009; 13: 1216-21.
4.    Sadique J, Chandra T, Thenmozhi V, Elango V. Biochemical modes of action of Cassia occidentalis and Cardiospermum halicacabum in inflammation. J Ethnopharmacol. 1987; 19(2): 201-212.
5.    Dalziel JM. Useful Plants of West Tropical Africa. Crown Agents for Overseas Governments, London. 1956; 179-183.
6.    Mohammed M, Aboki MA, Saidu HM, Victor O, Tawakalitu A, Maikano SA. Phytochemical and Some Antimicrobial Activity of Cassia Occidentalis L. (Caesalpiniaceae). Int J Sci Technol. 2012; 2(4).
7.    S. R. Tambe, S.D. Sawant. Determination of Terconazole from Biological Matrix by HPTLC and It’s Characterization by MS. Asian J. Pharm. Ana. 2014; 4(3): 108-112.  
8.    Cheng S C, Huang MZ, Shiea J. Thin layer chromatography/mass spectrometry. Journal of Chromatography A. 2011; 1218(19): 2700-11.
9.    Meghal Patel. Development and Validation of Simultaneous Estimation of Two Catecholamines in Combine Dosage Form by HPTLC Method. Asian J. Pharm. Ana. 2014; 4(2): 57-77.
10.    Rashmin C. Introduction to HPLC. www.pharmainfo.net.
11.    Practice modern TLC. Seventh edition, Peter EW, Royal Chemical Society, London.
12.    Archita J Patel, Dharati M Joshi, Manisha S. Choyal, Bhargav D. Patel. Development and validation of stability indicating HPTLC method for simultaneous estimation of Fluocinolone acetonide and Miconazole nitrate in Ointment. Asian J. Pharm. Ana. 2015; 5(2): 49-60.
13.    Freedberg I, Eisen A, Wolff K, Austen KF, Goldsmith LA, Katz S. Fitzpatrick's dermatology in general medicine. McGraw-Hill Co. 2003; 6th ed. pp. 407–427, 814–847,1106,1164–1204, 1876–1877,1994–2014.
14.    Lookingbill D, Marks J. Principles of Dermatology. PA: WB Saunders Co. 1993; 2nd ed. pp. 204-214.
15.    V. Jain, Tripti Jain, Swarnlata Saraf, S. Saraf. HPTLC method for routine quality control of Ayurvedic formulation Drakshadi gutka. Asian J. Pharm. Ana. 2013; 3(4): 111-114.
16.    World Health Organization, Quality Control Methods For Medicinal Plants Materials, Geneva, 1998, 1-15.
17.    Laxman M. Prajapati, Anjali Patel, Jimish R. Patel, Amit K. Joshi, Mohammadali Kharodiya. High-Performance Thin Layer Chromatography Method for Simultaneous Estimation of Cefepime Hydrochloride and Sulbactam Sodium. Asian J. Pharm. Ana. 2016; 6(4): 207-212.
18.    Validation of analytical procedures: text and methodology Q2(R1), ICH Harmonized Tripartite Guidelines, (2005). Available from: URL: http://www.ich.org/LOB/media/MEDIA417.pdf
19.    Prashant B. Patil. Azilsartan: A Review of Analytical Methods for Estimation in Pharmaceutical Formulation. Asian J. Pharm. Ana. 2018; 8(4): 227-232. doi 10.5958/2231-5675.2018.00041.87.
20.    Ramasamy Arivukkarasu, Aiyalu Rajasekaran. Detection and Quantification of Anti-oxidant markers like Rutin, Catechin, Quercetin, Gallic acid, Ellagic acid, Ferulic acid, Vitexin, and Mangiferin in Herbal raw materials available in the market belong to Rutaceae family by HPTLC Technique. Asian Journal of Pharmaceutical Analysis. 2021; 11(2):151-5. doi: 10.52711/2231-5675.2021.00026
21.    Bauer R et al.Pharmaceutical quality, standardization, and normalization of phytopharmaceuticals (in German). Z Phytother. 1994; 15: 82–91.
22.    S.K. Purohit, R. Solanki, V. Mathur, M. Mathur. Evaluation of Wound Healing Activity of Ethanolic Extract of Curcuma longa Rhizomes in Male Albino Rats. Asian J. Pharm. Res. 2013; 3(2): 79-81.
23.    Harshmohan. Textbook of Pathology. Jaypee Brothers, New Delhi. 2005.
24.    Naidu Narapusetty, O. Sivaiah, B. Balanasaraiah, M. Haranadhbabu, B. Prasad, B. Hosanna Crown, Ch. M. M. Prasada Rao. Anti-Inflammatory Activity of Ethanolic Extract of Basella alba in Acute and Sub-acute Model. Asian J. Pharm. Res. 2017; 7(2): 88-93. doi: 10.5958/2231-5691.2017.00015.6
25.    Manjit Singh, Vijender Kumar, Anti-inflammatory activity of aqueous extract of Mirabilis jalapa Linn. Leaves. Pharmacognosy Research. 2011; 2(6): 364–367.
26.    Prajakta P Shinde, Shahu D Khule, Sneha Sonawane, Suvarna Shelke. Analgesic activity and anti-inflammatory activity of methanolic extract of plant Sida cordata in carrageenan-induced paw edema in rats. Asian Journal of Pharmaceutical Research. 2021; 11(3): 143-6. doi: 10.52711/2231-5691.2021.00027
27.    Agrawal SS, M Paridhavi. Herbal Drug Technology. University Press. 1-25.
28.    Kokate CK, Purohit AP and S. B. Gokhale. Pharmacognosy, Nirali Prakashan Publications. 28th Edition, 1.4-1.8.

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank

Journal Policies & Information


Recent Articles




Tags


Not Available