Author(s):
Rajesh Sinha, Rahul Singh, Manisha Chandrakar, Arun KS Parihar
Email(s):
arunpharma1986@gmail.com
DOI:
10.52711/0974-360X.2024.00028 
Address:
Rajesh Sinha2, Rahul Singh3, Manisha Chandrakar4, Arun KS Parihar1,2*
1Drug Testing Laboratory Evam Anusandhan Kendra, Raipur (C.G) 492010.
2University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G), 492010.
3M.J. College, Junwani Road, Kohka, Bhilai (C.G), 490023.
4M.J. College, Junwani Road, Kohka, Bhilai (C.G), 490023.
*Corresponding Author
Published In:
Volume - 17,
Issue - 1,
Year - 2024
ABSTRACT:
Nanoemulsions are most promising delivery system for the natural bioactives compounds which posses poor bioavailability due to low solubility. Nanoemulsions as dosage delivery system and formulations have been found to be suitable for loading high amount of drugs to improve its therapeutic effect. These are widely used in cosmetics, diagnostic, drug therapies and bioactives because of the nanosized formulation. In the present work, nanoemulsion formulations of curcumin were prepared by using the tamarind gum as emulsifier using hot homogenization method. The six batches (F1, F2, F3, F4, F5 and F6) of nanoformulations were prepared and optimized on the basis of particle size and zeta potential. The optimized nanoemulsion (F3) which one reported to have particle size of 173.5 ±nm with zeta potential of -33.2±mV. The drug content was found to be 70% and the particles were found to be spherical, smooth and non-aggregated. The formulation were found to be stable in tested conditions. Thus, tamarind gum as a natural polymer can be used as stabilising, gelling, thickening, binding and muco- adhesive agents for formulation of novel drug delivery system of various drugs.
Cite this article:
Rajesh Sinha, Rahul Singh, Manisha Chandrakar, Arun KS Parihar. Designing of Curcumin nanoemulsion by using Tamarind gum as Natural Emulsifying agent. Research Journal of Pharmacy and Technology. 2024; 17(1):172-8. doi: 10.52711/0974-360X.2024.00028
Cite(Electronic):
Rajesh Sinha, Rahul Singh, Manisha Chandrakar, Arun KS Parihar. Designing of Curcumin nanoemulsion by using Tamarind gum as Natural Emulsifying agent. Research Journal of Pharmacy and Technology. 2024; 17(1):172-8. doi: 10.52711/0974-360X.2024.00028 Available on: https://rjptonline.org/AbstractView.aspx?PID=2024-17-1-28
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