Author(s): Lidia Kamal Al-Halaseh, Rawan Al-Suhaimat, Duaa Al-Suhaimat, Teeb Al-Adaileh, Maha Nour Abu Hajleh, Ali Mahmoud Al-Samydai, Rehan Alkasasbeh, Manal Nahar Al Soub, Wael Abu Dayyih


DOI: 10.52711/0974-360X.2023.00728   

Address: Lidia Kamal Al-Halaseh1*, Rawan Al-Suhaimat1, Duaa Al-Suhaimat2, Teeb Al-Adaileh2, Maha Nour Abu Hajleh3, Ali Mahmoud Al-Samydai4, Rehan Alkasasbeh2, Manal Nahar Al Soub1, Wael Abu Dayyih1
1Department of Pharmaceutical Chemistry, Faulty of Pharmacy, Mutah University, Zip code (61710), Al-Karak, Jordan.
2Department of Pharmaceutical Science, Faulty of Pharmacy, Mutah University, Zip code (61710), Al-Karak, Jordan.
3Department of Cosmetic Science, Pharmacological and Dagnostic Research Centre, Faculty of Allied Medical Science, Al-Ahliyya Amman University, Zip code (19328), Amman, Jordan.
4Pharmacological and Diagnostic Research Centre, Faculty of Pharmacy, Al-Ahliyya Amman University, Zip code (19328), Amman, Jordan.
*Corresponding Author

Published In:   Volume - 16,      Issue - 9,     Year - 2023

Nanotechnology innovations have a positive impact on multidisciplinary health sectors, in particular, drug delivery. Variable nanocarriers were utilized in order to decrease systemic toxicity and enhance the delivery of drug particles to the targeted tissues. Systemic delivery of medicines through the pulmonary route of administration is still within limited boundaries. Delivering medicines loaded into nanoparticles through the pulmonary route for treating chronic and acute diseases such as diabetes, cancers, and even hormone therapy would be a novelty. Nanocarriers include lipid nanoparticles, liposomes, nano-emulsions, solid lipid nanoparticles, non-structured lipid carriers, and Multifarious inhaled Lipid-Based Nanocarriers. Promising results were obtained after delivering cytotoxic, hypoglycemic and anabolic agents. Although revolution in drug delivery and enhancements of drug efficacy are predicted, limitations and health hazards have to be taken into consideration. Physical stability, high loading capacity, good adhesion to the pulmonary wall are among the formulation supremacy. Also from a patient perspective, inhaled drugs carried by nanoparticles have minor side effects, faster response, more convenience to carry, and wide dosage intervals. Disadvantages range from expelling the minute particles which could result in delivering sub-effective doses to more serious health problems such as increased thrombosis activity.

Cite this article:
Lidia Kamal Al-Halaseh, Rawan Al-Suhaimat, Duaa Al-Suhaimat, Teeb Al-Adaileh, Maha Nour Abu Hajleh, Ali Mahmoud Al-Samydai, Rehan Alkasasbeh, Manal Nahar Al Soub, Wael Abu Dayyih. Revolutionized Drug Delivery by using Pulmonary Nanotechnology: A Review. Research Journal of Pharmacy and Technology 2023; 16(9):4462-8. doi: 10.52711/0974-360X.2023.00728

Lidia Kamal Al-Halaseh, Rawan Al-Suhaimat, Duaa Al-Suhaimat, Teeb Al-Adaileh, Maha Nour Abu Hajleh, Ali Mahmoud Al-Samydai, Rehan Alkasasbeh, Manal Nahar Al Soub, Wael Abu Dayyih. Revolutionized Drug Delivery by using Pulmonary Nanotechnology: A Review. Research Journal of Pharmacy and Technology 2023; 16(9):4462-8. doi: 10.52711/0974-360X.2023.00728   Available on:

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