Author(s): Vinod Gauttam, Kavita Munjal, Anchal Arora, Somdutt Mujwar, Isha Rani, Sumeet Gupta, Showkat R Mir

Email(s): kavitamunjal915@gmail.com

DOI: 10.52711/0974-360X.2023.00576   

Address: Vinod Gauttam1, Kavita Munjal2*, Anchal Arora3, Somdutt Mujwar4, Isha Rani5, Sumeet Gupta6, Showkat R Mir7
1IES Institute of Pharmacy, IES University, Bhopal, Madhya Pradesh, India.
2*Department of Pharmacy, Amity Institute of Pharmacy, Amity University, Noida, Uttar Pradesh, India.
3Department of Pharmacology, All India Institute of Medical Sciences, Bathinda, Punjab, India.
4Department of Pharmacy, Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India.
5Department of Pharmacy, Spurthy College of Pharmacy, Marasur Gate, Bangalore, Karnataka, India.
6Department of Pharmacy, M.M. College of Pharmacy, M.M. (Deemed to be University), Mullana, Ambala, Haryana, India.
7Department of Pharmacognosy & Phytochemistry, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 7,     Year - 2023


ABSTRACT:
Cinnamon is a tropical evergreen tree that belongs to the Lauraceae family. It has long been used as a spice and is historically used for flavouring food and in pharmaceutical preparations to treat a variety of diseases. The material on Cinnamomum's pharmacological activities is fragmented and lacking in well-documented form. We attempted to compile its extensive medical and pharmacological features, as well as current patents awarded on Cinnamomum uses around the world, in this review.


Cite this article:
Vinod Gauttam, Kavita Munjal, Anchal Arora, Somdutt Mujwar, Isha Rani, Sumeet Gupta, Showkat R Mir. A Review on Pharmacological Activities and Recent Patents on Cinnamomum species. Research Journal of Pharmacy and Technology 2023; 16(7):3489-3. doi: 10.52711/0974-360X.2023.00576

Cite(Electronic):
Vinod Gauttam, Kavita Munjal, Anchal Arora, Somdutt Mujwar, Isha Rani, Sumeet Gupta, Showkat R Mir. A Review on Pharmacological Activities and Recent Patents on Cinnamomum species. Research Journal of Pharmacy and Technology 2023; 16(7):3489-3. doi: 10.52711/0974-360X.2023.00576   Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-7-73


7. REFERENCES:
1.    Kumar S, Kumari R, Mishra S. Pharmacological properties and their medicinal uses of Cinnamomum: a review. Journal of Pharmacy and Pharmacology. 2019; 71(12):1735-1761. doi: 10.1111/jphp.13173.
2.    Anonymus, 1992. The Wealth of India - A Dictionary of Indian Raw Materials & Industrial Products. Council of Scientific & Industrial Research, New Delhi.
3.    Chericoni S, Prieto JM, Iacopini P, Cioni P, Morelli I. In vitro activity of the essential oil of Cinnamomum zeylanicum and eugenol in peroxynitrite-induced oxidative processes. Journal of Agricultural and Food Chemistry. 2005; 53: 4762-4765. doi: 10.1021/jf050183e.
4.    Jayaprakasha GK, Rao LJM. Chemistry, Biogenesis, and Biological Activities of Cinnaomomum zeylanicum. Critical Reviews in Food Science and Nutrition. 2011; 51:547-562. doi.org/10.1080/10408391003699550.
5.    Kapoor IPS, Singh B, Singh G, Isidorov V, Szczpaniak L. Chemistry, antimicrobial and antioxidant potentials of Cinnamomum tamala Nees and Eberm. (Tejpat) essential oil and oleoresins. Natural Product Radiance. 2009; 8(2):106-116. doi: http://hdl.handle.net/123456789/4042
6.    Zaidi SF, Aziz M, Muhammad JS, Kadowaki M. Review: Diverse pharmacological properties of Cinnamomum cassia: A review. Pakistan Journal of Pharmaceutical Sciences. 2015; 28:1433-1438.
7.    Guptha MHRK, Bavya, HL Prasad K, MN Adiga S, Adiga US. Combined effects of E. jambolana and C. zeylanicum extract in insulin resistance associated structural and functional hepatic changes in high fructose-fed rats. Research J Pharm and Tech. 2019; 12 (12):5765-5772. doi: 10.5958/0974-360X.2019.00998.3
8.    Li R, Laing T, Xu L, Li Y, Zhang S, Duan X. Protective effect of cinnamon polyphenols against STZ-diabetic mice fed high-sugar, high-fat diet and its underlying mechanism. Food and Chemical Toxicology. 2013; 51:419-425. doi: 10.1016/j.fct.2012.10.024.
9.    Couturier K, Hininger I, Poulet L, Anderson RA, Roussel AM, Canini F et al. Cinnamon intake alleviates the combined effects of dietary-induced insulin resistance and acute stress on brain mitochondria. The Journal of Nutritional Biochemistry. 2016; 28:183-190. doi: 10.1016/j.jnutbio.2015.10.016.
10.    Shah M, Panchal M. Ethnopharmacological properties of Cinnamomum tamala - a review. International Journal of Pharmaceutical Sciences Review and Research. 2010; 5: 141-144.
11.    Malik J, Munjal K, Deshmukh R. Attenuating effect of standardized lyophilized Cinnamomum zeylanicum bark extract against streptozotocin-induced experimental dementia of Alzheimer’s type. Journal of Basic and Clinical Physiology and Pharmacology. 2015. 26(3):275-285. doi: 10.1515/jbcpp-2014-0012
12.    Ho SC, Chang KS, Chang PW. Inhibition of neuroinflammation by cinnamon and its components. Food Chemistry. 2013; 138:2275-2282. doi: 10.1016/j.foodchem
13.    Chaurasia KJ, Mishra A, Tripathi YB. Immunomodulatory property of hexane fraction of leaves of Cinnamomum tamala Linn. in rats. Cell Biochemistry and Function. 2010; 28:454-460. doi: 10.1002/cbf.1677.
14.    Lee JH, Park DH, Lee S, Seo HJ, Park SJ, Jung K, Kim S-Y, Kang S. Potential and beneficial effects of Cinnamomum cassia on gastritis and safety: Literature review and analysis of standard extract. Applied Biology Cehmistry. 2021. 64:1-14. doi.org/10.1186/s13765-021-00661-y
15.    Eswaran BM, Surendran S, Vijayakumar M, Ohja S, Rawat AKS, Rao CV. Gastroprotective activity of Cinnamomum tamala leaves on gastric ulcers in rats. Journal of Ethnopharmacology. 2010; 128:537-540. doi: 10.1016/j.jep.2010.01.036.
16.    Askari F, Rashidkhani B, Hekmatdoost A. Cinnamon may have therapeutic benefits on lipid profile, lipd enzymes, insulin resistance, and high-sensitiviry C-reactive protein in noalcholic fatty liver disease patients. Nutrition Research. 2015; 34:143-148. doi: 10.1016/j.nutres.2013.11.005.
17.    Lopez JJ, Jardin I, Salido GM, Rosado JA. Cinnamtannin B-1as an antioxidant and plateletlet aggregation inhibitor. Life Sciences. 2008; 82: 977-982. doi: 10.1016/j.lfs.2008.03.009.
18.    Moselhy SS, Ali HKH. Hepatoprotective effect of cinnamon against carbon tetrachloride induced oxidative stress and liver injury in rats. Biological Research. 2010; 42: 93-98.
19.    Thamizhselvam N, Krishana Yathi K, Sanjaya Kumar YR, Sarawathy VN, Venugopalan TN, Jaya N. Hepatoprotective activity of methanolic extract of Cinnamomum tamala against paracetamol intoxicated Swiss albino mice. Ayu. 2010; 1: 1-13. doi: 10.4103/0974-8520.123133
20.    Kumar A, Mansoori N, Munjal K, Dahiya G, Dwivedi V, Choudhary M. Comparative Efficacy Study of A Polyherbal Formulation With Other Available Drugs In Propiobacterium Acnes Induced Rat Model. European Journal of Biomedical and Pharmaceutical Sciences. 2019. 6(1):362-374.
21.    Hong CH, Hur SK, Oh OJ, Kim SS, Nam KA, Lee SK. Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells. Journal of Ethnopharmacology. 2002; 83:153-159. doi: 10.1016/s0378-8741(02)00205-2.
22.    Goyal P, Chauhan A, Kaushik P. Laboratory evaluation of crude extracts of Cinnamomum tamala for potential antibacterial activity. Electronic Journal of Biology. 2009; 5:75-79.
23.    Sundar S, Padmalatha K, Helasri G, Vasanthi M, Narmada BS, Lekhya B, Jyothi N, Sravani T. Anti-microbial activity of aqueous extract of natural preservatives – Cumin, Cinnamon, Coriander and Mint. Research Journal of Pharmacy and Technology. 2016; 9(7):843-847. doi: 10.5958/0974-360X.2016.00159.1  
24.    Chandrasekaran S, Geetha RV. Antimicrobial activity of the three essential oils on oral pathogens. Research Journal of Pharmacy and Technology. 2014. 7(10):1128-1129.
25.    Choi O, Cho SK, Kim J, Park CG, Kim J. In vitro antibacterial activity and major bioactive components of Cinnamomum verum essential oils against cariogenic bacteria, Streptococcus mutans and Streptococcus sobrinus. Asian Pacific Journal of Tropical Biomedicine. 2016. 6:308-314. https://doi.org/10.1016/j.apjtb.2016.01.007
26.    Subramanian S, Shenoy PA, Pai V. Antimicrobial activity of some essential oils and extracts from natural sources on skin and soft tissue infection causing microbes. An in-vitro study. Research Journal of Pharmacy and Technology. 2021. 14(7):3603-3609. https://doi.org/10.52711/0974-360X.2021.00623
27.    Premanathan M, Rajendran S, Ramanathan T, Kathiresan K, Nakashima H, Yamamoton N. A survey of some Indian medicinal plants for anti-human immunodeficiency virus (HIV) activity. Indian Journal of Medical Research. 2000. 112: 73-77.
28.    Cisarova M, Tancinova D, Medo J, Kacaniova M. The in vitro effect of selected essential oils on the growth and mycotoxin production of Aspergillus species. Journal of Environmental Science and Health B. 2016. 51:668-674. doi: 10.1080/03601234.2016.1191887.
29.    Munjal K, Ahmad S, Gupta A, Haye A, Amin S, Mir SR. Polyphenol-enriched fraction and the compounds isolated from Garcinia indica fruits ameliorate obesity through suppression of digestive enzymes and oxidative stress. Pharmacognosy Magazine. 2020; 16(70):236-245. doi: 10.4103/pm.pm_587_19
30.    Munjal K, Sharma S, Sharma S, Kumar D, Choudhary A, Berwal R, Kumar R. Comparison of serum 25-hydroxyvitamin D levels after a single oral dose of vitamin D3 formulations in mild vitamin D3 deficiency. Journal of Pharmacology and Pharmacotherapeutics. 2022; 12(4):163-167. Doi: 10.4103/jpp.jpp_105_21


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